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Seroprevalence of human T-lymphotropic virus HTLV and its associated factors in donors of a blood bank of Medellín-Colombia, 2014-2018

التفاصيل البيبلوغرافية
العنوان: Seroprevalence of human T-lymphotropic virus HTLV and its associated factors in donors of a blood bank of Medellín-Colombia, 2014-2018
المؤلفون: Cardona Arias, Jaiberth antonio, Vélez-Quintero C., Calle-González O.V., Florez-Duque J., Zapata J.C.
بيانات النشر: Public Library of Science
سنة النشر: 2019
مصطلحات موضوعية: ADOLESCENT, ADULT, AGED, ARTICLE, BLOOD, BLOOD BANK, BLOOD BANKS, BLOOD DONOR, BLOOD DONORS, BLOOD SAFETY, BLOOD SAMPLING, COLOMBIA, CONTROLLED STUDY, CROSS-SECTIONAL STUDIES, CROSS-SECTIONAL STUDY, CHEMOLUMINESCENCE, FEMALE, HTLV-1 INFECTION, HTLV-2 INFECTION, HTLV-I INFECTIONS, HTLV-II INFECTIONS, HUMAN, HUMAN T-LYMPHOTROPIC VIRUS 1, HUMAN T-LYMPHOTROPIC VIRUS 2, HUMANS, MAJOR CLINICAL STUDY, MALE, MIDDLE AGED, NONHUMAN, POPULATION RESEARCH
الوصف: Background Research on HTLV in Colombia is limited; despite being an endemic country there are few studies on the magnitude of this infection. The aim of this study was to determine the seroprevalence of HTLV I/II and its associated factors in donors to a blood bank of Medellín Colombia, 2014-2018. Methods This is a cross-sectional study of 52,159 donors with a secondary information source. Seroprevalence of HTLV I/II was determined with its confidence interval and the population characteristics were described by frequency and summary measures. To explore the associated factors, Pearson's Chi square test, Mann-Whitney U test, crude odds ratios were used and they were adjusted by logistic regression in SPSS 25.0. Results 88% of the population lived in the metropolitan area, 68.5% belonged to the University. 76.2% were altruistic donors (unpaid donors who did not donate to a specific patient). 24.5% were repetitive (paid) donors. 75% of the donors were under 41 years old. The seroprevalence of HTLV I/II was 0.176% (95% CI = 0.139% -0.213%), being statistically lower in repetitive donors and men. Conclusion The seroprevalence of HTLV I/II infection in the studied blood bank is lower than that reported in other blood banks at the departmental and national levels. In Medellín, it was associated with the frequency of donation and gender, which is useful information for the hemovigilance programs of the city. © 2019 Cardona-Arias et al. ; jaiberth.cardona@campusucc.edu.co
نوع الوثيقة: article in journal/newspaper
وصف الملف: e0221060
اللغة: unknown
تدمد: 19326203
العلاقة: Plos One; https://doi.org/10.1371/journal.pone.0221060Test; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85070725316&doi=10.1371%2fjournal.pone.0221060&partnerID=40&md5=8df24101e834820108e0d17c6c0d81ecTest; https://hdl.handle.net/20.500.12494/51080Test; Cardona Arias Jaiberth antonio,Vélez-Quintero C.,Calle-González O.V.,Florez-Duque J.,Zapata J.C.Seroprevalence of human T-lymphotropic virus HTLV and its associated factors in donors of a blood bank of Medellín-Colombia, 2014-2018.Plos One. 2019. 14. (8): e0221060
DOI: 10.1371/journal.pone.0221060
الإتاحة: https://doi.org/20.500.12494/51080Test
https://doi.org/10.1371/journal.pone.0221060Test
https://hdl.handle.net/20.500.12494/51080Test
حقوق: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.A2491436
قاعدة البيانات: BASE
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