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Vitamin D Deficiency and Neurologic Outcome After Sudden Cardiac Arrest

التفاصيل البيبلوغرافية
العنوان: Vitamin D Deficiency and Neurologic Outcome After Sudden Cardiac Arrest
المساهمون: Jung-Joon Cha, Jin Wi, Wi, Jin
بيانات النشر: Lippincott Williams & Wilkins
سنة النشر: 2019
مصطلحات موضوعية: Adult, Aged, Death, Sudden, Cardiac, Disease-Free Survival, Female, Humans, Male, Middle Aged, Nervous System Diseases* / blood, Nervous System Diseases* / etiology, Nervous System Diseases* / mortality, Sex Factors, Survival Rate, Vitamin D Deficiency* / blood, Vitamin D Deficiency* / complications, Vitamin D Deficiency* / mortality, Cerebral performance category, resuscitation, sudden cardiac arrest, vitamin D deficiency
الوصف: Background: Vitamin D deficiency is related to various cardiovascular diseases, including sudden cardiac arrest (SCA). This study investigated the association of vitamin D level with neurologic outcome and mortality after resuscitation from SCA. Patients and Methods: We enrolled patients who were successfully resuscitated from out-of-hospital cardiac arrest of presumed cardiac cause in Severance Cardiovascular Hospital as a prospective cohort registry. Baseline blood samples including pH, lactate, and vitamin D were obtained without fluid replacement just after hospital admission. Outcome was assessed by cerebral performance category (CPC) score at 1 month after SCA. Favorable outcome was defined as survival with CPC score of 1 or 2, whereas unfavorable one as death or survival with CPC scores of 3 through 5. Severe vitamin D deficiency was defined as 25(OH)D <10 ng/mL. Results: A total of 163 patients were included. Overall 96 (59%) patients had a favorable neurologic outcome, whereas 67 patients (41%) showed unfavorable outcome, including 37 (23%) mortality. Patients with unfavorable outcome were likely to be female and have initial non-shockable rhythm, longer arrest time, severe shock, diabetes, and baseline renal dysfunction. In multivariate analysis, severe vitamin D deficiency was one of the poor prognostic factors of both unfavorable neurologic outcome and mortality after SCA. Conclusions: Vitamin D deficiency is very prevalent and strongly associated with both unfavorable neurologic outcome and mortality in patients resuscitated from SCA. ; restriction
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 1073-2322
1540-0514
31524672
العلاقة: SHOCK; J02658; OAK-2022-02614; https://ir.ymlib.yonsei.ac.kr/handle/22282913/189238Test; https://journals.lww.com/shockjournal/Fulltext/2019/12000/Vitamin_D_Deficiency_and_Neurologic_Outcome_After.17.aspxTest; T9992019236; SHOCK, Vol.52(6) : E146-E152, 2019-12
DOI: 10.1097/SHK.0000000000001335
الإتاحة: https://doi.org/10.1097/SHK.0000000000001335Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/189238Test
https://journals.lww.com/shockjournal/Fulltext/2019/12000/Vitamin_D_Deficiency_and_Neurologic_Outcome_After.17.aspxTest
حقوق: CC BY-NC-ND 2.0 KR
رقم الانضمام: edsbas.939F26FC
قاعدة البيانات: BASE
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