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Obesity and loss of disease-free years owing to major non-communicable diseases: a multicohort study

التفاصيل البيبلوغرافية
العنوان: Obesity and loss of disease-free years owing to major non-communicable diseases: a multicohort study
المؤلفون: Mark Hamer, Maria Nordin, Joni V Lindbohm, G David Batty, Tea Lallukka, Markku Koskenvuo, Markus Jokela, Mika Kivimäki, Joshua A Bell, Archana Singh-Manoux, Linda L Magnusson Hanson, Jane E Ferrie, Ida E H Madsen, Reiner Rugulies, Ossi Rahkonen, Tuula Oksanen, Sari Stenholm, Solja T Nyberg, Marie Zins, Martin J Shipley, Jussi Vahtera, Constanze Leineweber, Marianna Virtanen, Katriina Heikkilä, Lars Alfredsson, Marcel Goldberg, Peter J M Westerholm, Jaana Pentti, Töres Theorell, Eleonor I Fransson, Sakari Suominen, Olli Pietiläinen, Anders Knutsson, Hugo Westerlund
المساهمون: tyks, vsshp, tyks, vsshp, kansanterveystiede, Public Health, 2607307
بيانات النشر: ELSEVIER SCI LTD
United Kingdom
Britannia
GB
سنة النشر: 2022
المجموعة: University of Turku: UTUPub / Turun yliopisto
الوصف: Background Obesity increases the risk of several chronic diseases, but the extent to which the obesity-related loss of disease-free years varies by lifestyle category and across socioeconomic groups is unclear. We estimated the number of years free from major non-communicable diseases in adults who are overweight and obese, compared with those who are normal weight.Methods We pooled individual-level data on body-mass index (BMI) and non-communicable diseases from men and women with no initial evidence of these diseases in European cohort studies from the Individual-Participant-Data Meta-Analysis in Working Populations consortium. BMI was assessed at baseline (1991-2008) and non-communicable diseases (incident type 2 diabetes, coronary heart disease, stroke, cancer, asthma, and chronic obstructive pulmonary disease) were ascertained via linkage to records from national health registries, repeated medical examinations, or self-report. Disease-free years from age 40 years to 75 years associated with underweight (BMI <18.5 kg/m(2)), overweight (>= 25 kg/m(2) to <30 kg/m(2)), and obesity (class I [mild] >= 30 kg/m(2) to < 35 kg/m(2); class II-III [severe] >= 35 kg/m(2)) compared with normal weight (>= 18.5 kg/m(2) to <25 kg/m(2)) were estimated.Findings Of 137 503 participants from ten studies, we excluded 6973 owing to missing data and 10 349 with prevalent disease at baseline, resulting in an analytic sample of 120 181 participants. Of 47 127 men, 211 (0.4%) were underweight, 21 468 (45.6%) normal weight, 20 738 (44.0%) overweight, 3982 (8.4%) class I obese, and 728 (1.5%) class II-III obese. The corresponding numbers among the 73 054 women were 1493 (2.0%), 44 760 (61.3%), 19 553 (26.8%), 5670 (7.8%), and 1578 (2.2%), respectively. During 1 328 873 person-years at risk (mean follow-up 11.5 years [range 6.3-18.6]), 8159 men and 8100 women developed at least one non-communicable disease. Between 40 years and 75 years, the estimated number of disease-free years was 29.3 (95% CI 28.8-29.8) in ...
نوع الوثيقة: other/unknown material
وصف الملف: E490; E497
اللغة: English
تدمد: 2468-2667
العلاقة: Lancet Public Health; 10; https://www.utupub.fi/handle/10024/158590Test; URN:NBN:fi-fe2021042720105
الإتاحة: https://www.utupub.fi/handle/10024/158590Test
رقم الانضمام: edsbas.531EDF12
قاعدة البيانات: BASE
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