دورية أكاديمية
Non-Traditional Systemic Treatments for Diabetic Retinopathy: An Evidence-Based Review
| العنوان: | Non-Traditional Systemic Treatments for Diabetic Retinopathy: An Evidence-Based Review |
|---|---|
| المؤلفون: | Simo, Rafael, Ballarini, Stefania, Cunha-Vaz, Jose, Ji, Linong, Haller, Hermann, Zimmet, Paul, Wong, Tien Y. |
| المساهمون: | Simo, R (reprint author), Univ Autonoma Barcelona, Vall DHebron Res Inst, Diabet & Metab Reseach Unit, Pg Vall DHebron 119-129, Barcelona 08035, Spain., Univ Autonoma Barcelona, Vall DHebron Res Inst, Diabet & Metab Reseach Unit, Barcelona 08035, Spain., ISCIII, Ctr Invest Biomed Red Diabet & Enfermedad Metab A, Barcelona 08035, Spain., Vifor Pharma OM Pharma, Global Med Affairs Infect Dis OTX, Geneva, Switzerland., Univ Coimbra, AIBILI Assoc Innovat & Biomed Res Light & Image, Diabet Retinopathy & Retinal Vasc Dis, European Vis Inst Clin Res Network EVICR Net,Opht, P-3000548 Coimbra, Portugal., Peking Univ, Peoples Hosp, Dept Endocrinol & Metab, Beijing, Peoples R China., Peking Univ, Ctr Diabet, Beijing, Peoples R China., MHH, Dept Hypertens & Nephrol, Hannover, Germany., Baker IDI Heart & Diabet Inst, Victor Smorgon Diabet Ctr, Melbourne, Vic 3004, Australia., Natl Univ Singapore, Duke NUS Grad Med Sch, Singapore Natl Eye Ctr, Singapore Eye Res Inst, Singapore 117548, Singapore., Univ Autonoma Barcelona, Vall DHebron Res Inst, Diabet & Metab Reseach Unit, Pg Vall DHebron 119-129, Barcelona 08035, Spain. |
| المصدر: | SCI |
| بيانات النشر: | CURRENT MEDICINAL CHEMISTRY |
| سنة النشر: | 2015 |
| المجموعة: | Peking University Institutional Repository (PKU IR) / 北京大学机构知识库 |
| مصطلحات موضوعية: | Calcium dobesilate, diabetic retinopathy, fenofibrate, renin-angiotensin system blockade, RANDOMIZED CONTROLLED-TRIAL, DOXIUM CALCIUM DOBESILATE, ENDOTHELIAL GROWTH-FACTOR, BLOOD-PRESSURE CONTROL, MICROVASCULAR COMPLICATIONS, DOUBLE-BLIND, VISUAL-LOSS, ANTIOXIDANT PROPERTIES, GLOBAL PREVALENCE, MEDICAL-TREATMENT |
| الوصف: | The rapid escalation in the global prevalence diabetes, with more than 30% being afflicted with diabetic retinopathy (DR), means it is likely that associated vision-threatening conditions will also rise substantially. This means that new therapeutic approaches need to be found that go beyond the current standards of diabetic care, and which are effective in the early stages of the disease. In recent decades several new pharmacological agents have been investigated for their effectiveness in preventing the appearance and progression of DR or in reversing DR; some with limited success while others appear promising. This up-to-date critical review of non-traditional systemic treatments for DR is based on the published evidence in MEDLINE spanning 1980-December 2014. It discusses a number of therapeutic options, paying particular attention to the mechanisms of action and the clinical evidence for the use of renin-angiotensin system blockade, fenofibrate and calcium dobesilate monohydrate in DR. ; SCI(E) ; ARTICLE ; rafael.simo@vhir.org ; 21 ; 2580-2589 ; 22 |
| نوع الوثيقة: | journal/newspaper |
| اللغة: | English |
| تدمد: | 0929-8673 1875-533X |
| العلاقة: | CURRENT MEDICINAL CHEMISTRY.2015,22,(21),2580-2589.; 1314965; http://hdl.handle.net/20.500.11897/421110Test; WOS:000358868600006 |
| الإتاحة: | https://doi.org/20.500.11897/421110Test https://hdl.handle.net/20.500.11897/421110Test |
| رقم الانضمام: | edsbas.36D42F98 |
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