رسالة جامعية
أعرض في EDS

Évaluation des pratiques de l’anticoagulation dans la fibrillation atriale non valvulaire. Les anticoagulants oraux directs ont-ils changé nos habitudes de prescription ? Étude à partir de deux cohortes dans le service de cardiologie au Centre Hospitalier de Périgueux

التفاصيل البيبلوغرافية
العنوان: Évaluation des pratiques de l’anticoagulation dans la fibrillation atriale non valvulaire. Les anticoagulants oraux directs ont-ils changé nos habitudes de prescription ? Étude à partir de deux cohortes dans le service de cardiologie au Centre Hospitalier de Périgueux
المؤلفون: Belval, Julien
المساهمون: Université de Bordeaux (UB), Philippe Jarnier
المصدر: https://dumas.ccsd.cnrs.fr/dumas-01157257Test ; Médecine humaine et pathologie. 2015.
بيانات النشر: HAL CCSD
سنة النشر: 2015
المجموعة: DUMAS (Dépôt Universitaire de Mémoires Après Soutenance)
مصطلحات موضوعية: Fibrillation atriale, Anticoagulant oral direct, Anti-vitamine K, Accident vasculaire cérébral, CHA2DS2-VASC, HAS-BLED, Évaluation de pratiques, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
الوصف: Introduction: The Atrial Fibrillation (AF) is a common and serious pathology associated to a high risk of stroke. Despite their effectiveness, Vitamin K Antagonists (VKA) are underused with high-risk patients. We tried to understand anticoagulation practice at the Perigueux's hospital in the AF and assess the impact of the use of Novel Oral Anticoagulants (NOACs). Method: Two groups of patients in AF has been involved in 2012 and 2013 in the quantitative retrospective observational study, the first one cured by VKA only, the second by both VKA and NOAC. We studied characteristics and treatments according to CHA2DS2-VASC and those cured effectively. Results: Eligible cured and non-cured patients are statically comparable in the two groups for their age (p=0.3 in 2012, p=0.1 in 2013) and the CHA2DS2-VASC (p=0.57 in 2012, p=0.12 in 2013). The proportion of cured eligible patients is comparable between the two groups, around 77 % (p=0.95), despite the use of NOACs to 22.8% of eligible patients cured in 2013. Patients with NOAC are statically younger (p<0.001), lower bleeding risk (p=0.0019) and thrombo-embolism (p<0.001). The anemia, previous bleeding history, bleeding risk assessed by HAS-BLED, antiplatelet therapy and falling risk are the main reasons to not cure. Conclusion: There is a satisfactory proportion of eligible cured patients compared to the previous studies but the choice of non-curing is not always justified. After only one year, NOACs did not improve our practice. ; Introduction : La fibrillation atriale est une pathologie fréquente et grave associée à un risque accru d’accident vasculaire cérébral. Malgré leur efficacité reconnue, les anti-vitamines K (AVK) restent sous utilisés chez les patients les plus à risque. Nous avons cherché à connaître les pratiques de l’anticoagulation au Centre Hospitalier de Périgueux dans la fibrillation atriale (FA) et évaluer l’impact de l’arrivée des anticoagulants oraux directs (AOD). Méthode : Deux cohortes de patients en FA ont été incluses en 2012 et 2013 ...
نوع الوثيقة: master thesis
اللغة: French
العلاقة: dumas-01157257; https://dumas.ccsd.cnrs.fr/dumas-01157257Test; https://dumas.ccsd.cnrs.fr/dumas-01157257/documentTest; https://dumas.ccsd.cnrs.fr/dumas-01157257/file/Med_generale_2015_Belval.pdfTest
الإتاحة: https://dumas.ccsd.cnrs.fr/dumas-01157257Test
https://dumas.ccsd.cnrs.fr/dumas-01157257/documentTest
https://dumas.ccsd.cnrs.fr/dumas-01157257/file/Med_generale_2015_Belval.pdfTest
حقوق: info:eu-repo/semantics/OpenAccess
رقم الانضمام: edsbas.27C5D2D9
قاعدة البيانات: BASE
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