Paraneoplastic hypercalcemia in clear cell ovarian adenocarcinoma
| العنوان: | Paraneoplastic hypercalcemia in clear cell ovarian adenocarcinoma |
|---|---|
| المؤلفون: | Lewin, S, Dezube, D, Guddati, AK, Mittal, K, Muggia, F, Klein, Paula |
| المصدر: | ecancermedicalscience |
| بيانات النشر: | Cancer Intelligence, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | endocrine system diseases, PTHrP, paraneoplastic, hypercalcemia, ovarian, Case Report, clear cell adenocarcinoma |
| الوصف: | Background: Hypercalcemia has been reported in association with a number of malignancies, but it is an unusual manifestation of ovarian cancer. This finding at presentation (possibly aggravated by oral calcium intake) led to discovery of a clear cell carcinoma of the ovary. The implications and pathophysiology of this association are reviewed. Case report: Following presentation with abdominal symptoms, this premenopausal woman was found to have bilateral adnexal masses and hypercalcemia. Her parathormone-related polypeptide was found to be elevated. After surgery and staging, she received adjuvant carboplatin and paclitaxel (later substituted by docetaxel). She has done well on her long-term follow-up. Conclusions: This rare paraneoplastic manifestation of ovarian cancer may be associated with long-term survival if discovered at an early stage. In this instance, further benefit may have been obtained from adjuvant platinum-based chemotherapy. |
| اللغة: | English |
| تدمد: | 1754-6605 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid________::b6e3c9297aa9dc31df4ae98ba76a035dTest http://europepmc.org/articles/PMC3463128Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid..........b6e3c9297aa9dc31df4ae98ba76a035d |
| قاعدة البيانات: | OpenAIRE |
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