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From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development

التفاصيل البيبلوغرافية
العنوان:	From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development
المؤلفون:	Jiachao Wang, Lin Wei, Shibo Jiang, Shan Su, Lanying Du, Cuiqing Ma
المصدر:	Microbes and Infection
بيانات النشر:	Elsevier BV, 2020.
سنة النشر:	2020
مصطلحات موضوعية:	0301 basic medicine, HCoV-19, COVID-19 Vaccines, Coronavirus disease 2019 (COVID-19), Human coronavirus, Cross Protection, viruses, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pneumonia, Viral, 030106 microbiology, Immunology, Biology, Severe Acute Respiratory Syndrome, medicine.disease_cause, Microbiology, Article, Betacoronavirus, 03 medical and health sciences, Broad spectrum, Pandemic, medicine, Animals, Humans, skin and connective tissue diseases, Pandemics, Coronavirus, SARS-CoV-2, Viral Vaccine, fungi, COVID-19, virus diseases, SARS-CoV, Viral Vaccines, Cellular receptor, biology.organism_classification, Virology, body regions, 030104 developmental biology, Infectious Diseases, Vaccines, Inactivated, 2019-nCoV, Coronavirus Infections, Vaccine, Cross-protection
الوصف:	The global pandemic of COVID-19 caused by SARS-CoV-2 (also known as 2019-nCoV and HCoV-19) has posed serious threats to public health and economic stability worldwide, thus calling for development of vaccines against SARS-CoV-2 and other emerging and reemerging coronaviruses. Since SARS-CoV-2 and SARS-CoV have high similarity of their genomic sequences and share the same cellular receptor (ACE2), it is essential to learn the lessons and experiences from the development of SARS-CoV vaccines for the development of SARS-CoV-2 vaccines. In this review, we summarized the current knowledge on the advantages and disadvantages of the SARS-CoV vaccine candidates and prospected the strategies for the development of safe, effective and broad-spectrum coronavirus vaccines for prevention of infection by currently circulating SARS-CoV-2 and other emerging and reemerging coronaviruses that may cause future epidemics or pandemics.
تدمد:	1286-4579
الوصول الحر:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c649cf0d813fc73eb7c566da79e6d6f3Test https://doi.org/10.1016/j.micinf.2020.05.004Test
حقوق:	OPEN
رقم الانضمام:	edsair.doi.dedup.....c649cf0d813fc73eb7c566da79e6d6f3
قاعدة البيانات:	OpenAIRE

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