Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ
| العنوان: | Lung CD4+ T-cells in patients with lung fibrosis produce pro-fibrotic interleukin-13 together with interferon-γ |
|---|---|
| المؤلفون: | Frode L. Jahnsen, Johny Kongerud, Liv Ingunn Bjoner Sikkeland, May Brit Lund, Pål Aukrust, Shuo-Wang Qiao, Tone Sjåheim, Łukasz Wyrożemski, Øyvind Molberg, Espen S. Baekkevold, Thor Ueland, Ole Henrik Myrdal |
| المصدر: | European Respiratory Journal. 57:2000983 |
| بيانات النشر: | European Respiratory Society (ERS), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | CD4-Positive T-Lymphocytes, Pulmonary and Respiratory Medicine, Interleukin-13, Lung, business.industry, Pulmonary Fibrosis, medicine.medical_treatment, Lung fibrosis, respiratory system, Phenotype, Interferon-gamma, Text mining, Cytokine, medicine.anatomical_structure, Immunology, Interleukin 13, Humans, Medicine, In patient, business |
| الوصف: | This study identified an unusual phenotype of clonally expanded CD4 T-cells in BAL in lung fibrosis characterised by co-production of pro-fibrotic cytokine IL-13 and pro-inflammatory cytokine IFN-γ. These cells may be a promising target for therapy.https://bit.ly/2TgzWCXTest |
| تدمد: | 1399-3003 0903-1936 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cc2b952a733f11bd49aa13ba334ab6Test https://doi.org/10.1183/13993003.00983-2020Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b9cc2b952a733f11bd49aa13ba334ab6 |
| قاعدة البيانات: | OpenAIRE |
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