The activity of interferon on ultraviolet light-induced squamous cell carcinomas in mice
| العنوان: | The activity of interferon on ultraviolet light-induced squamous cell carcinomas in mice |
|---|---|
| المؤلفون: | R. Donald Hudson, Edgar B. Smith, Homer S. Black, Eduardo Tschen, W. Robert Fleischmann, Miriam M. Brysk |
| المصدر: | Journal of the American Academy of Dermatology. 5(1) |
| سنة النشر: | 1981 |
| مصطلحات موضوعية: | Mice, Hairless, Neoplasms, Radiation-Induced, Skin Neoplasms, Tumor size, Ultraviolet Rays, Cell, Dermatology, Neoplasms, Experimental, Biology, Mice, medicine.anatomical_structure, Immune system, Virus type, Interferon, Immunology, medicine, Ultraviolet light, Cancer research, Carcinoma, Squamous Cell, Animals, Tumor growth, Interferons, Ultraviolet radiation, medicine.drug |
| الوصف: | The activity of interferons was tested in ultraviolet light-induced skin tumors in mice. After the tumors were well established, they were injected and measured daily for 19 days. Mouse virus type (IF-alpha + IF-beta) and immune (IF-gamma) interferons were injected intralesionally into three groups of test animals and compared with a fourth group which received mock interferon (control). When used separately, virus type and immune interferons did not affect tumor growth; however, we observed regression in tumor size when the two interferons were used in combination. |
| تدمد: | 0190-9622 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0871884447db254ac695c6955e03d5eTest https://pubmed.ncbi.nlm.nih.gov/6168672Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....b0871884447db254ac695c6955e03d5e |
| قاعدة البيانات: | OpenAIRE |
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