Frequent Transient Hepatitis C viremia without Seroconversion among Healthcare Workers in Cairo, Egypt

التفاصيل البيبلوغرافية
العنوان: Frequent Transient Hepatitis C viremia without Seroconversion among Healthcare Workers in Cairo, Egypt
المؤلفون: Mohamed Momen, Diaa Marzouk, Jacques Izopet, Matthew L. Albert, Hanan Said Ezz elarab, Mostafa El-Hosini, Aline Munier, Elisabeth Delarocque-Astagneau, Omar Okasha, Lénaig Le Fouler, Mona Rafik, Mai El-Daly, Mostafa K. Mohamed, Rasha Mamdouh, Sylvia Taylor, Mohamed Abdel-Hamid, Dalia G. Sos, Florence Abravanel, Arnaud Fontanet, Waleed Salah Eldin
المساهمون: Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), Université Ain Shams, Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), National Hepatology & Tropical Medicine Research Institute, Menoufia University, National Liver Institute [Menoufia, Egypt], Menoufia University [Egypte]-Menoufia University [Egypte], Faculty of medicine, Immunobiologie des Cellules Dendritiques, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Minia University, This work was supported by the Agence nationale de recherches sur le Sida et les Hépatites virales,France, grant number ANRS 12171, We gratefully thank the healthcare workers who accepted to be part of the study. We are grateful to Dina Aly and Ghada Wassef, Faculty of Medicine, Ain Shams University, Cairo, for their help in monitoring follow-up of HCWs, to Melissa Laird, Institut Pasteur/INSERM, for her collaboration in the immunology team, to all participating prick injury clinics, to Prof. Ghada Ismail, Head of Central Unit for Infection Control in Ain Shams and her staff, to Prof. Wagida Anwar, Head of Department of Community, Environmental and Occupational Medicine at the Faculty of Medicine, Ain Shams University, Cairo, and to Prof. Ahmed Nassar, Dean of Ain Shams University Hospital, for allowing the conduct of the study in Ain Shams University hospitals., Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Vougny, Marie-Christine
المصدر: PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (2), pp.e57835. ⟨10.1371/journal.pone.0057835⟩
PLoS ONE, 2013, 8 (2), pp.e57835. ⟨10.1371/journal.pone.0057835⟩
PLoS ONE, Vol 8, Iss 2, p e57835 (2013)
بيانات النشر: Public Library of Science, 2013.
سنة النشر: 2013
مصطلحات موضوعية: Male, Non-Clinical Medicine, Epidemiology, Gastroenterology and hepatology, Health Care Providers, MESH: Occupational Exposure/statistics & numerical data, MESH: Viremia/epidemiology, MESH: Egypt/epidemiology, medicine.disease_cause, MESH: Hepatitis C/transmission, Hepatitis, Cohort Studies, 0302 clinical medicine, Health care, Medicine, 030212 general & internal medicine, Prospective Studies, Young adult, 0303 health sciences, education.field_of_study, Multidisciplinary, virus diseases, Hepatitis C, 3. Good health, Infectious hepatitis, MESH: Young Adult, MESH: Hepatitis C/blood, [SDV.IMM]Life Sciences [q-bio]/Immunology, Infectious diseases, Egypt, Female, Public Health, Viral load, Research Article, Adult, [SDV.IMM] Life Sciences [q-bio]/Immunology, Clinical Research Design, Science, Hepatitis C virus, Health Personnel, Population, Viremia, Viral diseases, MESH: Viremia/transmission, MESH: Hepatitis C/epidemiology, Infectious Disease Epidemiology, 03 medical and health sciences, Young Adult, Environmental health, Occupational Exposure, Humans, Seroconversion, MESH: Health Personnel/statistics & numerical data, education, Liver diseases, 030304 developmental biology, MESH: Humans, business.industry, MESH: Adult, medicine.disease, Virology, MESH: Male, digestive system diseases, MESH: Viremia/blood, business, MESH: Female
الوصف: BackgroundsWith 10% of the general population aged 15-59 years chronically infected with hepatitis C virus (HCV), Egypt is the country with the highest HCV prevalence worldwide. Healthcare workers (HCWs) are therefore at particularly high risk of HCV infection. Our aim was to study HCV infection risk after occupational blood exposure among HCWs in Cairo.Methodology/principal findingsThe study was conducted in 2008-2010 at Ain Shams University Hospital, Cairo. HCWs reporting an occupational blood exposure at screening, having neither anti-HCV antibodies (anti-HCV) nor HCV RNA, and exposed to a HCV RNA positive patient, were enrolled in a 6-month prospective cohort with follow-up visits at weeks 2, 4, 8, 12 and 24. During follow-up, anti-HCV, HCV RNA and ALT were tested. Among 597 HCWs who reported a blood exposure, anti-HCV prevalence at screening was 7.2%, not different from that of the general population of Cairo after age-standardization (11.6% and 10.4% respectively, p = 0.62). The proportion of HCV viremia among index patients was 37%. Of 73 HCWs exposed to HCV RNA from index patients, nine (12.3%; 95%CI, 5.8-22.1%) presented transient viremia, the majority of which occurred within the first two weeks after exposure. None of the workers presented seroconversion or elevation of ALT.Conclusions/significanceHCWs of a general University hospital in Cairo were exposed to a highly viremic patient population. They experienced frequent occupational blood exposures, particularly in early stages of training. These exposures resulted in transient viremic episodes without established infection. These findings call for further investigation of potential immune protection against HCV persistence in this high risk group.
وصف الملف: application/force-download
اللغة: English
تدمد: 1932-6203
2008-2010
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d3e9cdb2f1e6cf3d20768a840952dcTest
http://europepmc.org/articles/PMC3585182Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....89d3e9cdb2f1e6cf3d20768a840952dc
قاعدة البيانات: OpenAIRE
ResultId 1
Header edsair
OpenAIRE
edsair.doi.dedup.....89d3e9cdb2f1e6cf3d20768a840952dc
774
3

unknown
773.90234375
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsair&AN=edsair.doi.dedup.....89d3e9cdb2f1e6cf3d20768a840952dc&custid=s6537998&authtype=sso
FullText Array ( [Availability] => 0 )
Items Array ( [Name] => Title [Label] => Title [Group] => Ti [Data] => Frequent Transient Hepatitis C viremia without Seroconversion among Healthcare Workers in Cairo, Egypt )
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22Mohamed+Momen%22">Mohamed Momen</searchLink><br /><searchLink fieldCode="AR" term="%22Diaa+Marzouk%22">Diaa Marzouk</searchLink><br /><searchLink fieldCode="AR" term="%22Jacques+Izopet%22">Jacques Izopet</searchLink><br /><searchLink fieldCode="AR" term="%22Matthew+L%2E+Albert%22">Matthew L. Albert</searchLink><br /><searchLink fieldCode="AR" term="%22Hanan+Said+Ezz+elarab%22">Hanan Said Ezz elarab</searchLink><br /><searchLink fieldCode="AR" term="%22Mostafa+El-Hosini%22">Mostafa El-Hosini</searchLink><br /><searchLink fieldCode="AR" term="%22Aline+Munier%22">Aline Munier</searchLink><br /><searchLink fieldCode="AR" term="%22Elisabeth+Delarocque-Astagneau%22">Elisabeth Delarocque-Astagneau</searchLink><br /><searchLink fieldCode="AR" term="%22Omar+Okasha%22">Omar Okasha</searchLink><br /><searchLink fieldCode="AR" term="%22Lénaig+Le+Fouler%22">Lénaig Le Fouler</searchLink><br /><searchLink fieldCode="AR" term="%22Mona+Rafik%22">Mona Rafik</searchLink><br /><searchLink fieldCode="AR" term="%22Mai+El-Daly%22">Mai El-Daly</searchLink><br /><searchLink fieldCode="AR" term="%22Mostafa+K%2E+Mohamed%22">Mostafa K. Mohamed</searchLink><br /><searchLink fieldCode="AR" term="%22Rasha+Mamdouh%22">Rasha Mamdouh</searchLink><br /><searchLink fieldCode="AR" term="%22Sylvia+Taylor%22">Sylvia Taylor</searchLink><br /><searchLink fieldCode="AR" term="%22Mohamed+Abdel-Hamid%22">Mohamed Abdel-Hamid</searchLink><br /><searchLink fieldCode="AR" term="%22Dalia+G%2E+Sos%22">Dalia G. Sos</searchLink><br /><searchLink fieldCode="AR" term="%22Florence+Abravanel%22">Florence Abravanel</searchLink><br /><searchLink fieldCode="AR" term="%22Arnaud+Fontanet%22">Arnaud Fontanet</searchLink><br /><searchLink fieldCode="AR" term="%22Waleed+Salah+Eldin%22">Waleed Salah Eldin</searchLink> )
Array ( [Name] => Author [Label] => Contributors [Group] => Au [Data] => Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology<br />Pasteur-Cnam Risques infectieux et émergents (PACRI)<br />Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)<br />Université Ain Shams<br />Centre de Physiopathologie Toulouse Purpan (CPTP)<br />Université Toulouse III - Paul Sabatier (UT3)<br />Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)<br />National Hepatology & Tropical Medicine Research Institute<br />Menoufia University<br />National Liver Institute [Menoufia, Egypt]<br />Menoufia University [Egypte]-Menoufia University [Egypte]<br />Faculty of medicine<br />Immunobiologie des Cellules Dendritiques<br />Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)<br />Minia University<br />This work was supported by the Agence nationale de recherches sur le Sida et les Hépatites virales,France, grant number ANRS 12171<br />We gratefully thank the healthcare workers who accepted to be part of the study. We are grateful to Dina Aly and Ghada Wassef, Faculty of Medicine, Ain Shams University, Cairo, for their help in monitoring follow-up of HCWs<br />to Melissa Laird, Institut Pasteur/INSERM, for her collaboration in the immunology team, to all participating prick injury clinics<br />to Prof. Ghada Ismail, Head of Central Unit for Infection Control in Ain Shams and her staff<br />to Prof. Wagida Anwar, Head of Department of Community, Environmental and Occupational Medicine at the Faculty of Medicine, Ain Shams University, Cairo<br />and to Prof. Ahmed Nassar, Dean of Ain Shams University Hospital, for allowing the conduct of the study in Ain Shams University hospitals.<br />Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)<br />HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)<br />HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)<br />Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)<br />Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)<br />Vougny, Marie-Christine )
Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => PLoS ONE<br />PLoS ONE, Public Library of Science, 2013, 8 (2), pp.e57835. ⟨10.1371/journal.pone.0057835⟩<br />PLoS ONE, 2013, 8 (2), pp.e57835. ⟨10.1371/journal.pone.0057835⟩<br />PLoS ONE, Vol 8, Iss 2, p e57835 (2013) )
Array ( [Name] => Publisher [Label] => Publisher Information [Group] => PubInfo [Data] => Public Library of Science, 2013. )
Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2013 )
Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => <searchLink fieldCode="DE" term="%22Male%22">Male</searchLink><br /><searchLink fieldCode="DE" term="%22Non-Clinical+Medicine%22">Non-Clinical Medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Epidemiology%22">Epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%22Gastroenterology+and+hepatology%22">Gastroenterology and hepatology</searchLink><br /><searchLink fieldCode="DE" term="%22Health+Care+Providers%22">Health Care Providers</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Occupational+Exposure%2Fstatistics+%26+numerical+data%22">MESH: Occupational Exposure/statistics & numerical data</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Viremia%2Fepidemiology%22">MESH: Viremia/epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Egypt%2Fepidemiology%22">MESH: Egypt/epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%22medicine%2Edisease%5Fcause%22">medicine.disease_cause</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Hepatitis+C%2Ftransmission%22">MESH: Hepatitis C/transmission</searchLink><br /><searchLink fieldCode="DE" term="%22Hepatitis%22">Hepatitis</searchLink><br /><searchLink fieldCode="DE" term="%22Cohort+Studies%22">Cohort Studies</searchLink><br /><searchLink fieldCode="DE" term="%220302+clinical+medicine%22">0302 clinical medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Health+care%22">Health care</searchLink><br /><searchLink fieldCode="DE" term="%22Medicine%22">Medicine</searchLink><br /><searchLink fieldCode="DE" term="%22030212+general+%26+internal+medicine%22">030212 general & internal medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Prospective+Studies%22">Prospective Studies</searchLink><br /><searchLink fieldCode="DE" term="%22Young+adult%22">Young adult</searchLink><br /><searchLink fieldCode="DE" term="%220303+health+sciences%22">0303 health sciences</searchLink><br /><searchLink fieldCode="DE" term="%22education%2Efield%5Fof%5Fstudy%22">education.field_of_study</searchLink><br /><searchLink fieldCode="DE" term="%22Multidisciplinary%22">Multidisciplinary</searchLink><br /><searchLink fieldCode="DE" term="%22virus+diseases%22">virus diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Hepatitis+C%22">Hepatitis C</searchLink><br /><searchLink fieldCode="DE" term="%223%2E+Good+health%22">3. Good health</searchLink><br /><searchLink fieldCode="DE" term="%22Infectious+hepatitis%22">Infectious hepatitis</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Young+Adult%22">MESH: Young Adult</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Hepatitis+C%2Fblood%22">MESH: Hepatitis C/blood</searchLink><br /><searchLink fieldCode="DE" term="%22[SDV%2EIMM]Life+Sciences+[q-bio]%2FImmunology%22">[SDV.IMM]Life Sciences [q-bio]/Immunology</searchLink><br /><searchLink fieldCode="DE" term="%22Infectious+diseases%22">Infectious diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Egypt%22">Egypt</searchLink><br /><searchLink fieldCode="DE" term="%22Female%22">Female</searchLink><br /><searchLink fieldCode="DE" term="%22Public+Health%22">Public Health</searchLink><br /><searchLink fieldCode="DE" term="%22Viral+load%22">Viral load</searchLink><br /><searchLink fieldCode="DE" term="%22Research+Article%22">Research Article</searchLink><br /><searchLink fieldCode="DE" term="%22Adult%22">Adult</searchLink><br /><searchLink fieldCode="DE" term="%22[SDV%2EIMM]+Life+Sciences+[q-bio]%2FImmunology%22">[SDV.IMM] Life Sciences [q-bio]/Immunology</searchLink><br /><searchLink fieldCode="DE" term="%22Clinical+Research+Design%22">Clinical Research Design</searchLink><br /><searchLink fieldCode="DE" term="%22Science%22">Science</searchLink><br /><searchLink fieldCode="DE" term="%22Hepatitis+C+virus%22">Hepatitis C virus</searchLink><br /><searchLink fieldCode="DE" term="%22Health+Personnel%22">Health Personnel</searchLink><br /><searchLink fieldCode="DE" term="%22Population%22">Population</searchLink><br /><searchLink fieldCode="DE" term="%22Viremia%22">Viremia</searchLink><br /><searchLink fieldCode="DE" term="%22Viral+diseases%22">Viral diseases</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Viremia%2Ftransmission%22">MESH: Viremia/transmission</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Hepatitis+C%2Fepidemiology%22">MESH: Hepatitis C/epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%22Infectious+Disease+Epidemiology%22">Infectious Disease Epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%2203+medical+and+health+sciences%22">03 medical and health sciences</searchLink><br /><searchLink fieldCode="DE" term="%22Young+Adult%22">Young Adult</searchLink><br /><searchLink fieldCode="DE" term="%22Environmental+health%22">Environmental health</searchLink><br /><searchLink fieldCode="DE" term="%22Occupational+Exposure%22">Occupational Exposure</searchLink><br /><searchLink fieldCode="DE" term="%22Humans%22">Humans</searchLink><br /><searchLink fieldCode="DE" term="%22Seroconversion%22">Seroconversion</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Health+Personnel%2Fstatistics+%26+numerical+data%22">MESH: Health Personnel/statistics & numerical data</searchLink><br /><searchLink fieldCode="DE" term="%22education%22">education</searchLink><br /><searchLink fieldCode="DE" term="%22Liver+diseases%22">Liver diseases</searchLink><br /><searchLink fieldCode="DE" term="%22030304+developmental+biology%22">030304 developmental biology</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Humans%22">MESH: Humans</searchLink><br /><searchLink fieldCode="DE" term="%22business%2Eindustry%22">business.industry</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Adult%22">MESH: Adult</searchLink><br /><searchLink fieldCode="DE" term="%22medicine%2Edisease%22">medicine.disease</searchLink><br /><searchLink fieldCode="DE" term="%22Virology%22">Virology</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Male%22">MESH: Male</searchLink><br /><searchLink fieldCode="DE" term="%22digestive+system+diseases%22">digestive system diseases</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Viremia%2Fblood%22">MESH: Viremia/blood</searchLink><br /><searchLink fieldCode="DE" term="%22business%22">business</searchLink><br /><searchLink fieldCode="DE" term="%22MESH%3A+Female%22">MESH: Female</searchLink> )
Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => BackgroundsWith 10% of the general population aged 15-59 years chronically infected with hepatitis C virus (HCV), Egypt is the country with the highest HCV prevalence worldwide. Healthcare workers (HCWs) are therefore at particularly high risk of HCV infection. Our aim was to study HCV infection risk after occupational blood exposure among HCWs in Cairo.Methodology/principal findingsThe study was conducted in 2008-2010 at Ain Shams University Hospital, Cairo. HCWs reporting an occupational blood exposure at screening, having neither anti-HCV antibodies (anti-HCV) nor HCV RNA, and exposed to a HCV RNA positive patient, were enrolled in a 6-month prospective cohort with follow-up visits at weeks 2, 4, 8, 12 and 24. During follow-up, anti-HCV, HCV RNA and ALT were tested. Among 597 HCWs who reported a blood exposure, anti-HCV prevalence at screening was 7.2%, not different from that of the general population of Cairo after age-standardization (11.6% and 10.4% respectively, p = 0.62). The proportion of HCV viremia among index patients was 37%. Of 73 HCWs exposed to HCV RNA from index patients, nine (12.3%; 95%CI, 5.8-22.1%) presented transient viremia, the majority of which occurred within the first two weeks after exposure. None of the workers presented seroconversion or elevation of ALT.Conclusions/significanceHCWs of a general University hospital in Cairo were exposed to a highly viremic patient population. They experienced frequent occupational blood exposures, particularly in early stages of training. These exposures resulted in transient viremic episodes without established infection. These findings call for further investigation of potential immune protection against HCV persistence in this high risk group. )
Array ( [Name] => Format [Label] => File Description [Group] => SrcInfo [Data] => application/force-download )
Array ( [Name] => Language [Label] => Language [Group] => Lang [Data] => English )
Array ( [Name] => ISSN [Label] => ISSN [Group] => ISSN [Data] => 1932-6203<br />2008-2010 )
Array ( [Name] => URL [Label] => Access URL [Group] => URL [Data] => <link linkTarget="URL" linkTerm="https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d3e9cdb2f1e6cf3d20768a840952dc" linkWindow="_blank">https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d3e9cdb2f1e6cf3d20768a840952dc</link><br /><link linkTarget="URL" linkTerm="http://europepmc.org/articles/PMC3585182" linkWindow="_blank">http://europepmc.org/articles/PMC3585182</link> )
Array ( [Name] => Copyright [Label] => Rights [Group] => Cpyrght [Data] => OPEN )
Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsair.doi.dedup.....89d3e9cdb2f1e6cf3d20768a840952dc )
RecordInfo Array ( [BibEntity] => Array ( [Languages] => Array ( [0] => Array ( [Text] => English ) ) [Subjects] => Array ( [0] => Array ( [SubjectFull] => Male [Type] => general ) [1] => Array ( [SubjectFull] => Non-Clinical Medicine [Type] => general ) [2] => Array ( [SubjectFull] => Epidemiology [Type] => general ) [3] => Array ( [SubjectFull] => Gastroenterology and hepatology [Type] => general ) [4] => Array ( [SubjectFull] => Health Care Providers [Type] => general ) [5] => Array ( [SubjectFull] => MESH: Occupational Exposure/statistics & numerical data [Type] => general ) [6] => Array ( [SubjectFull] => MESH: Viremia/epidemiology [Type] => general ) [7] => Array ( [SubjectFull] => MESH: Egypt/epidemiology [Type] => general ) [8] => Array ( [SubjectFull] => medicine.disease_cause [Type] => general ) [9] => Array ( [SubjectFull] => MESH: Hepatitis C/transmission [Type] => general ) [10] => Array ( [SubjectFull] => Hepatitis [Type] => general ) [11] => Array ( [SubjectFull] => Cohort Studies [Type] => general ) [12] => Array ( [SubjectFull] => 0302 clinical medicine [Type] => general ) [13] => Array ( [SubjectFull] => Health care [Type] => general ) [14] => Array ( [SubjectFull] => Medicine [Type] => general ) [15] => Array ( [SubjectFull] => 030212 general & internal medicine [Type] => general ) [16] => Array ( [SubjectFull] => Prospective Studies [Type] => general ) [17] => Array ( [SubjectFull] => Young adult [Type] => general ) [18] => Array ( [SubjectFull] => 0303 health sciences [Type] => general ) [19] => Array ( [SubjectFull] => education.field_of_study [Type] => general ) [20] => Array ( [SubjectFull] => Multidisciplinary [Type] => general ) [21] => Array ( [SubjectFull] => virus diseases [Type] => general ) [22] => Array ( [SubjectFull] => Hepatitis C [Type] => general ) [23] => Array ( [SubjectFull] => 3. Good health [Type] => general ) [24] => Array ( [SubjectFull] => Infectious hepatitis [Type] => general ) [25] => Array ( [SubjectFull] => MESH: Young Adult [Type] => general ) [26] => Array ( [SubjectFull] => MESH: Hepatitis C/blood [Type] => general ) [27] => Array ( [SubjectFull] => [SDV.IMM]Life Sciences [q-bio]/Immunology [Type] => general ) [28] => Array ( [SubjectFull] => Infectious diseases [Type] => general ) [29] => Array ( [SubjectFull] => Egypt [Type] => general ) [30] => Array ( [SubjectFull] => Female [Type] => general ) [31] => Array ( [SubjectFull] => Public Health [Type] => general ) [32] => Array ( [SubjectFull] => Viral load [Type] => general ) [33] => Array ( [SubjectFull] => Research Article [Type] => general ) [34] => Array ( [SubjectFull] => Adult [Type] => general ) [35] => Array ( [SubjectFull] => [SDV.IMM] Life Sciences [q-bio]/Immunology [Type] => general ) [36] => Array ( [SubjectFull] => Clinical Research Design [Type] => general ) [37] => Array ( [SubjectFull] => Science [Type] => general ) [38] => Array ( [SubjectFull] => Hepatitis C virus [Type] => general ) [39] => Array ( [SubjectFull] => Health Personnel [Type] => general ) [40] => Array ( [SubjectFull] => Population [Type] => general ) [41] => Array ( [SubjectFull] => Viremia [Type] => general ) [42] => Array ( [SubjectFull] => Viral diseases [Type] => general ) [43] => Array ( [SubjectFull] => MESH: Viremia/transmission [Type] => general ) [44] => Array ( [SubjectFull] => MESH: Hepatitis C/epidemiology [Type] => general ) [45] => Array ( [SubjectFull] => Infectious Disease Epidemiology [Type] => general ) [46] => Array ( [SubjectFull] => 03 medical and health sciences [Type] => general ) [47] => Array ( [SubjectFull] => Young Adult [Type] => general ) [48] => Array ( [SubjectFull] => Environmental health [Type] => general ) [49] => Array ( [SubjectFull] => Occupational Exposure [Type] => general ) [50] => Array ( [SubjectFull] => Humans [Type] => general ) [51] => Array ( [SubjectFull] => Seroconversion [Type] => general ) [52] => Array ( [SubjectFull] => MESH: Health Personnel/statistics & numerical data [Type] => general ) [53] => Array ( [SubjectFull] => education [Type] => general ) [54] => Array ( [SubjectFull] => Liver diseases [Type] => general ) [55] => Array ( [SubjectFull] => 030304 developmental biology [Type] => general ) [56] => Array ( [SubjectFull] => MESH: Humans [Type] => general ) [57] => Array ( [SubjectFull] => business.industry [Type] => general ) [58] => Array ( [SubjectFull] => MESH: Adult [Type] => general ) [59] => Array ( [SubjectFull] => medicine.disease [Type] => general ) [60] => Array ( [SubjectFull] => Virology [Type] => general ) [61] => Array ( [SubjectFull] => MESH: Male [Type] => general ) [62] => Array ( [SubjectFull] => digestive system diseases [Type] => general ) [63] => Array ( [SubjectFull] => MESH: Viremia/blood [Type] => general ) [64] => Array ( [SubjectFull] => business [Type] => general ) [65] => Array ( [SubjectFull] => MESH: Female [Type] => general ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Frequent Transient Hepatitis C viremia without Seroconversion among Healthcare Workers in Cairo, Egypt [Type] => main ) ) ) [BibRelationships] => Array ( [HasContributorRelationships] => Array ( [0] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Mohamed Momen ) ) ) [1] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Diaa Marzouk ) ) ) [2] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Jacques Izopet ) ) ) [3] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Matthew L. Albert ) ) ) [4] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Hanan Said Ezz elarab ) ) ) [5] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Mostafa El-Hosini ) ) ) [6] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Aline Munier ) ) ) [7] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Elisabeth Delarocque-Astagneau ) ) ) [8] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Omar Okasha ) ) ) [9] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Lénaig Le Fouler ) ) ) [10] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Mona Rafik ) ) ) [11] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Mai El-Daly ) ) ) [12] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Mostafa K. Mohamed ) ) ) [13] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Rasha Mamdouh ) ) ) [14] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Sylvia Taylor ) ) ) [15] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Mohamed Abdel-Hamid ) ) ) [16] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Dalia G. Sos ) ) ) [17] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Florence Abravanel ) ) ) [18] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Arnaud Fontanet ) ) ) [19] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Waleed Salah Eldin ) ) ) [20] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology ) ) ) [21] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Pasteur-Cnam Risques infectieux et émergents (PACRI) ) ) ) [22] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM) ) ) ) [23] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Université Ain Shams ) ) ) [24] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Centre de Physiopathologie Toulouse Purpan (CPTP) ) ) ) [25] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Université Toulouse III - Paul Sabatier (UT3) ) ) ) [26] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) ) ) ) [27] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => National Hepatology & Tropical Medicine Research Institute ) ) ) [28] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Menoufia University ) ) ) [29] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => National Liver Institute [Menoufia, Egypt] ) ) ) [30] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Menoufia University [Egypte]-Menoufia University [Egypte] ) ) ) [31] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Faculty of medicine ) ) ) [32] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Immunobiologie des Cellules Dendritiques ) ) ) [33] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM) ) ) ) [34] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Minia University ) ) ) [35] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => This work was supported by the Agence nationale de recherches sur le Sida et les Hépatites virales,France, grant number ANRS 12171 ) ) ) [36] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => We gratefully thank the healthcare workers who accepted to be part of the study. We are grateful to Dina Aly and Ghada Wassef, Faculty of Medicine, Ain Shams University, Cairo, for their help in monitoring follow-up of HCWs ) ) ) [37] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => to Melissa Laird, Institut Pasteur/INSERM, for her collaboration in the immunology team, to all participating prick injury clinics ) ) ) [38] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => to Prof. Ghada Ismail, Head of Central Unit for Infection Control in Ain Shams and her staff ) ) ) [39] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => to Prof. Wagida Anwar, Head of Department of Community, Environmental and Occupational Medicine at the Faculty of Medicine, Ain Shams University, Cairo ) ) ) [40] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => and to Prof. Ahmed Nassar, Dean of Ain Shams University Hospital, for allowing the conduct of the study in Ain Shams University hospitals. ) ) ) [41] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM) ) ) ) [42] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM) ) ) ) [43] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM) ) ) ) [44] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) ) ) ) [45] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM) ) ) ) [46] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Vougny, Marie-Christine ) ) ) ) [IsPartOfRelationships] => Array ( [0] => Array ( [BibEntity] => Array ( [Dates] => Array ( [0] => Array ( [D] => 01 [M] => 02 [Type] => published [Y] => 2013 ) ) [Identifiers] => Array ( [0] => Array ( [Type] => issn-print [Value] => 19326203 ) [1] => Array ( [Type] => issn-print [Value] => 20082010 ) [2] => Array ( [Type] => issn-locals [Value] => edsair ) [3] => Array ( [Type] => issn-locals [Value] => edsairFT ) ) [Numbering] => Array ( [0] => Array ( [Type] => volume [Value] => 8 ) [1] => Array ( [Type] => issue [Value] => 2 ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => PLoS ONE [Type] => main ) ) ) ) ) ) )
IllustrationInfo