Efficacy of Combined Oral-Intravesical Oxybutynin Hydrochloride Treatment for Patients with Overactive Detrusors and Indwelling Urethral Catheters
العنوان: | Efficacy of Combined Oral-Intravesical Oxybutynin Hydrochloride Treatment for Patients with Overactive Detrusors and Indwelling Urethral Catheters |
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المؤلفون: | Müfit Akyüz, Necmettin Yildiz, Fusun Koseoglu, Murat Ersöz |
بيانات النشر: | LIPPINCOTT WILLIAMS & WILKINS, 2010. |
سنة النشر: | 2010 |
مصطلحات موضوعية: | Adult, Male, Oral treatment, medicine.medical_specialty, Turkey, medicine.drug_class, medicine.medical_treatment, Urethral Catheters, Urology, Administration, Oral, Oxybutynin hydrochloride, Physical Therapy, Sports Therapy and Rehabilitation, Urinary catheterization, Catheters, Indwelling, Anticholinergic, Humans, Medicine, Spinal Cord Injuries, General Nursing, Retrospective Studies, oxybutinin, hydrochloride, spinal cord injury, urodynamics, Urinary bladder, Urinary Bladder, Overactive, business.industry, Rehabilitation, Parasympatholytics, detrusor overactivity, indwelling urethral, catheter, intravesical, Retrospective cohort study, General Medicine, Urodynamics, Catheter, Administration, Intravesical, medicine.anatomical_structure, Mandelic Acids, Female, Urinary Catheterization, business |
الوصف: | The purpose of this article is to investigate the efficacy of intravesical oxybutynin hydrochloride (OH) to treat patients with overactive detrusors who are unresponsive to oral anticholinergic therapy alone. Twenty-five patients who were treated with oral OH for overactive detrusor (but who did not respond to treatment and were using indwelling urethral catheters) were given intravesical OH without changing oral treatment. Pre- and posttreatment bladder capacities were compared in urodynamic studies. The study showed that positive clinical results can be achieved with combined oral and intravesical OH treatments in patients with overactive detrusors who had indwelling urethral catheters because of severely reduced bladder capacity. However, a significant number of patients discontinued this treatment because of infection and difficulty in performing the procedure. Clinicians and rehabilitation nurses should provide education and support to eliminate these problems. In addition, the development of single-use standard sterile OH preparations for intravesical applications may increase the efficacy of the method. |
اللغة: | English |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f46d792c02a34a64215ccb7c30a74c4Test http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/20153Test |
حقوق: | CLOSED |
رقم الانضمام: | edsair.doi.dedup.....6f46d792c02a34a64215ccb7c30a74c4 |
قاعدة البيانات: | OpenAIRE |
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