Fluctuating hyper-hypocortisolaemia: a variant of Cushing's syndrome
| العنوان: | Fluctuating hyper-hypocortisolaemia: a variant of Cushing's syndrome |
|---|---|
| المؤلفون: | Anne White, Gil Leibowitz, David J. Gross, Moshe Hadani |
| المصدر: | Clinical endocrinology. 46(6) |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | Cortisol secretion, Adenoma, endocrine system, Pituitary gland, medicine.medical_specialty, Hydrocortisone, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Prohormone, Biology, Cushing syndrome, Endocrinology, Internal medicine, medicine, Humans, Pituitary Neoplasms, Cushing Syndrome, Middle Aged, medicine.disease, Combined Modality Therapy, Pathophysiology, Steroid hormone, medicine.anatomical_structure, Female, hormones, hormone substitutes, and hormone antagonists, Glucocorticoid, medicine.drug |
| الوصف: | We present a patient with severe Cushing's syndrome secondary to an invasive pituitary tumour. Cortisol secretion fluctuated between severe hypercortisolaemia associated with features of Cushing's syndrome to recurrent symptomatic hypocortisolaemia. Normal ACTH precursors to ACTH ratio during the various stages of cortisol secretion indicated that periodic decreased prohormone processing did not contribute to the unique presentation in the patient. Thus, the the extreme fluctuations of plasma cortisol levels are most probably due to unexplained erratic changes of ACTH secretion. |
| تدمد: | 0300-0664 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579a92d20b8d805723c361372a7e5b1fTest https://pubmed.ncbi.nlm.nih.gov/9274708Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....579a92d20b8d805723c361372a7e5b1f |
| قاعدة البيانات: | OpenAIRE |
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