أعرض في EDS

Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter

التفاصيل البيبلوغرافية
العنوان:	Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter
المؤلفون:	Jorg Taubel, Dorothée Camilleri, Boaz Mendzelevski, Anne Freier, Christopher S. Spencer, Claus Graff
المصدر:	Annals of Noninvasive Electrocardiology Mendzelevski, B, Spencer, C S, Freier, A, Camilleri, D, Graff, C & Täubel, J 2021, ' Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter ', Annals of Noninvasive Electrocardiology, vol. 26, no. 5, e12851 . https://doi.org/10.1111/anec.12851Test Annals of Noninvasive Electrocardiology, Vol 26, Iss 5, Pp n/a-n/a (2021)
سنة النشر:	2021
مصطلحات موضوعية:	Male, medicine.medical_specialty, resting ECG, Sample average, 030204 cardiovascular system & hematology, QT interval, 03 medical and health sciences, Electrocardiography, 0302 clinical medicine, Double-Blind Method, Consistency (statistics), Heart Rate, Physiology (medical), Internal medicine, Heart rate, medicine, Diseases of the circulatory (Cardiovascular) system, Humans, 030212 general & internal medicine, cardiovascular diseases, Lead (electronics), Cross-Over Studies, business.industry, AMPS/BRAVO, QT/cQT, Holter, Healthy subjects, General Medicine, Original Articles, Interval (music), GE Getemed, RC666-701, Ecg waveforms, Cardiology, Electrocardiography, Ambulatory, Female, Original Article, Cardiology and Cardiovascular Medicine, business
الوصف:	In clinical trials, traditionally only a limited number of 12‐lead resting electrocardiograms (ECGs) can be recorded and, thus, long intervals may elapse between assessment timepoints and valuable information may be missed during times when patients' cardiac electrical activity is not being monitored. These limitations have led to the increasing use of Holter recorders which provide continuous data registrations while reducing the burden on patients and freeing up time for clinical trial staff to perform other tasks. However, there is a shortage of data comparing the two approaches. In this study, data from a randomized, double‐blind, four‐period, crossover thorough QT study in 40 healthy subjects were used to compare continuous 12‐lead Holter recordings to standard 12‐lead resting ECGs which were recorded in parallel. Heart rate and QT interval data were estimated by averaging three consecutive heartbeats. Values exceeding the sample average by more than 5% were tagged as outliers and excluded from the analysis. Visual comparisons of the ECG waveforms of the Holter signal showed a good correlation with resting ECGs at matching timepoints. Resting ECG data revealed sex differences that Holter data did not show. Specifically, women were found to have a longer QTcF of 20 ms, while men had a lower heart rate. We found that continuous recordings provided a more accurate reflection of changes in cardiac electrical activity over 24 hr. However, manual adjudication is still required to ensure the quality and accuracy of ECG data, and that only artifacts are removed thereby avoiding loss of true signals.
وصف الملف:	application/pdf
تدمد:	1542-474X
الوصول الحر:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2262508e36f0fc2a002372238d5b49c0Test https://pubmed.ncbi.nlm.nih.gov/33949017Test
حقوق:	OPEN
رقم الانضمام:	edsair.doi.dedup.....2262508e36f0fc2a002372238d5b49c0
قاعدة البيانات:	OpenAIRE

ResultId	1
Header	edsair OpenAIRE edsair.doi.dedup.....2262508e36f0fc2a002372238d5b49c0 859 3 unknown 858.5732421875
PLink	https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsair&AN=edsair.doi.dedup.....2262508e36f0fc2a002372238d5b49c0&custid=s6537998&authtype=sso
FullText	Array ( [Availability] => 0 )
Items	Array ( [Name] => Title [Label] => Title [Group] => Ti [Data] => Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter ) Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22Jorg+Taubel%22">Jorg Taubel</searchLink><br /><searchLink fieldCode="AR" term="%22Dorothée+Camilleri%22">Dorothée Camilleri</searchLink><br /><searchLink fieldCode="AR" term="%22Boaz+Mendzelevski%22">Boaz Mendzelevski</searchLink><br /><searchLink fieldCode="AR" term="%22Anne+Freier%22">Anne Freier</searchLink><br /><searchLink fieldCode="AR" term="%22Christopher+S%2E+Spencer%22">Christopher S. Spencer</searchLink><br /><searchLink fieldCode="AR" term="%22Claus+Graff%22">Claus Graff</searchLink> ) Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => Annals of Noninvasive Electrocardiology<br />Mendzelevski, B, Spencer, C S, Freier, A, Camilleri, D, Graff, C & Täubel, J 2021, ' Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter ', Annals of Noninvasive Electrocardiology, vol. 26, no. 5, e12851 . https://doi.org/10.1111/anec.12851<br />Annals of Noninvasive Electrocardiology, Vol 26, Iss 5, Pp n/a-n/a (2021) ) Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2021 ) Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => <searchLink fieldCode="DE" term="%22Male%22">Male</searchLink><br /><searchLink fieldCode="DE" term="%22medicine%2Emedical%5Fspecialty%22">medicine.medical_specialty</searchLink><br /><searchLink fieldCode="DE" term="%22resting+ECG%22">resting ECG</searchLink><br /><searchLink fieldCode="DE" term="%22Sample+average%22">Sample average</searchLink><br /><searchLink fieldCode="DE" term="%22030204+cardiovascular+system+%26+hematology%22">030204 cardiovascular system & hematology</searchLink><br /><searchLink fieldCode="DE" term="%22QT+interval%22">QT interval</searchLink><br /><searchLink fieldCode="DE" term="%2203+medical+and+health+sciences%22">03 medical and health sciences</searchLink><br /><searchLink fieldCode="DE" term="%22Electrocardiography%22">Electrocardiography</searchLink><br /><searchLink fieldCode="DE" term="%220302+clinical+medicine%22">0302 clinical medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Double-Blind+Method%22">Double-Blind Method</searchLink><br /><searchLink fieldCode="DE" term="%22Consistency+%28statistics%29%22">Consistency (statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Heart+Rate%22">Heart Rate</searchLink><br /><searchLink fieldCode="DE" term="%22Physiology+%28medical%29%22">Physiology (medical)</searchLink><br /><searchLink fieldCode="DE" term="%22Internal+medicine%22">Internal medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Heart+rate%22">Heart rate</searchLink><br /><searchLink fieldCode="DE" term="%22medicine%22">medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases+of+the+circulatory+%28Cardiovascular%29+system%22">Diseases of the circulatory (Cardiovascular) system</searchLink><br /><searchLink fieldCode="DE" term="%22Humans%22">Humans</searchLink><br /><searchLink fieldCode="DE" term="%22030212+general+%26+internal+medicine%22">030212 general & internal medicine</searchLink><br /><searchLink fieldCode="DE" term="%22cardiovascular+diseases%22">cardiovascular diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Lead+%28electronics%29%22">Lead (electronics)</searchLink><br /><searchLink fieldCode="DE" term="%22Cross-Over+Studies%22">Cross-Over Studies</searchLink><br /><searchLink fieldCode="DE" term="%22business%2Eindustry%22">business.industry</searchLink><br /><searchLink fieldCode="DE" term="%22AMPS%2FBRAVO%22">AMPS/BRAVO</searchLink><br /><searchLink fieldCode="DE" term="%22QT%2FcQT%22">QT/cQT</searchLink><br /><searchLink fieldCode="DE" term="%22Holter%22">Holter</searchLink><br /><searchLink fieldCode="DE" term="%22Healthy+subjects%22">Healthy subjects</searchLink><br /><searchLink fieldCode="DE" term="%22General+Medicine%22">General Medicine</searchLink><br /><searchLink fieldCode="DE" term="%22Original+Articles%22">Original Articles</searchLink><br /><searchLink fieldCode="DE" term="%22Interval+%28music%29%22">Interval (music)</searchLink><br /><searchLink fieldCode="DE" term="%22GE+Getemed%22">GE Getemed</searchLink><br /><searchLink fieldCode="DE" term="%22RC666-701%22">RC666-701</searchLink><br /><searchLink fieldCode="DE" term="%22Ecg+waveforms%22">Ecg waveforms</searchLink><br /><searchLink fieldCode="DE" term="%22Cardiology%22">Cardiology</searchLink><br /><searchLink fieldCode="DE" term="%22Electrocardiography%2C+Ambulatory%22">Electrocardiography, Ambulatory</searchLink><br /><searchLink fieldCode="DE" term="%22Female%22">Female</searchLink><br /><searchLink fieldCode="DE" term="%22Original+Article%22">Original Article</searchLink><br /><searchLink fieldCode="DE" term="%22Cardiology+and+Cardiovascular+Medicine%22">Cardiology and Cardiovascular Medicine</searchLink><br /><searchLink fieldCode="DE" term="%22business%22">business</searchLink> ) Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => In clinical trials, traditionally only a limited number of 12‐lead resting electrocardiograms (ECGs) can be recorded and, thus, long intervals may elapse between assessment timepoints and valuable information may be missed during times when patients' cardiac electrical activity is not being monitored. These limitations have led to the increasing use of Holter recorders which provide continuous data registrations while reducing the burden on patients and freeing up time for clinical trial staff to perform other tasks. However, there is a shortage of data comparing the two approaches. In this study, data from a randomized, double‐blind, four‐period, crossover thorough QT study in 40 healthy subjects were used to compare continuous 12‐lead Holter recordings to standard 12‐lead resting ECGs which were recorded in parallel. Heart rate and QT interval data were estimated by averaging three consecutive heartbeats. Values exceeding the sample average by more than 5% were tagged as outliers and excluded from the analysis. Visual comparisons of the ECG waveforms of the Holter signal showed a good correlation with resting ECGs at matching timepoints. Resting ECG data revealed sex differences that Holter data did not show. Specifically, women were found to have a longer QTcF of 20 ms, while men had a lower heart rate. We found that continuous recordings provided a more accurate reflection of changes in cardiac electrical activity over 24 hr. However, manual adjudication is still required to ensure the quality and accuracy of ECG data, and that only artifacts are removed thereby avoiding loss of true signals. ) Array ( [Name] => Format [Label] => File Description [Group] => SrcInfo [Data] => application/pdf ) Array ( [Name] => ISSN [Label] => ISSN [Group] => ISSN [Data] => 1542-474X ) Array ( [Name] => URL [Label] => Access URL [Group] => URL [Data] => <link linkTarget="URL" linkTerm="https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2262508e36f0fc2a002372238d5b49c0" linkWindow="_blank">https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2262508e36f0fc2a002372238d5b49c0</link><br /><link linkTarget="URL" linkTerm="https://pubmed.ncbi.nlm.nih.gov/33949017" linkWindow="_blank">https://pubmed.ncbi.nlm.nih.gov/33949017</link> ) Array ( [Name] => Copyright [Label] => Rights [Group] => Cpyrght [Data] => OPEN ) Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsair.doi.dedup.....2262508e36f0fc2a002372238d5b49c0 )
RecordInfo	Array ( [BibEntity] => Array ( [Languages] => Array ( [0] => Array ( [Text] => Undetermined ) ) [Subjects] => Array ( [0] => Array ( [SubjectFull] => Male [Type] => general ) [1] => Array ( [SubjectFull] => medicine.medical_specialty [Type] => general ) [2] => Array ( [SubjectFull] => resting ECG [Type] => general ) [3] => Array ( [SubjectFull] => Sample average [Type] => general ) [4] => Array ( [SubjectFull] => 030204 cardiovascular system & hematology [Type] => general ) [5] => Array ( [SubjectFull] => QT interval [Type] => general ) [6] => Array ( [SubjectFull] => 03 medical and health sciences [Type] => general ) [7] => Array ( [SubjectFull] => Electrocardiography [Type] => general ) [8] => Array ( [SubjectFull] => 0302 clinical medicine [Type] => general ) [9] => Array ( [SubjectFull] => Double-Blind Method [Type] => general ) [10] => Array ( [SubjectFull] => Consistency (statistics) [Type] => general ) [11] => Array ( [SubjectFull] => Heart Rate [Type] => general ) [12] => Array ( [SubjectFull] => Physiology (medical) [Type] => general ) [13] => Array ( [SubjectFull] => Internal medicine [Type] => general ) [14] => Array ( [SubjectFull] => Heart rate [Type] => general ) [15] => Array ( [SubjectFull] => medicine [Type] => general ) [16] => Array ( [SubjectFull] => Diseases of the circulatory (Cardiovascular) system [Type] => general ) [17] => Array ( [SubjectFull] => Humans [Type] => general ) [18] => Array ( [SubjectFull] => 030212 general & internal medicine [Type] => general ) [19] => Array ( [SubjectFull] => cardiovascular diseases [Type] => general ) [20] => Array ( [SubjectFull] => Lead (electronics) [Type] => general ) [21] => Array ( [SubjectFull] => Cross-Over Studies [Type] => general ) [22] => Array ( [SubjectFull] => business.industry [Type] => general ) [23] => Array ( [SubjectFull] => AMPS/BRAVO [Type] => general ) [24] => Array ( [SubjectFull] => QT/cQT [Type] => general ) [25] => Array ( [SubjectFull] => Holter [Type] => general ) [26] => Array ( [SubjectFull] => Healthy subjects [Type] => general ) [27] => Array ( [SubjectFull] => General Medicine [Type] => general ) [28] => Array ( [SubjectFull] => Original Articles [Type] => general ) [29] => Array ( [SubjectFull] => Interval (music) [Type] => general ) [30] => Array ( [SubjectFull] => GE Getemed [Type] => general ) [31] => Array ( [SubjectFull] => RC666-701 [Type] => general ) [32] => Array ( [SubjectFull] => Ecg waveforms [Type] => general ) [33] => Array ( [SubjectFull] => Cardiology [Type] => general ) [34] => Array ( [SubjectFull] => Electrocardiography, Ambulatory [Type] => general ) [35] => Array ( [SubjectFull] => Female [Type] => general ) [36] => Array ( [SubjectFull] => Original Article [Type] => general ) [37] => Array ( [SubjectFull] => Cardiology and Cardiovascular Medicine [Type] => general ) [38] => Array ( [SubjectFull] => business [Type] => general ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter [Type] => main ) ) ) [BibRelationships] => Array ( [HasContributorRelationships] => Array ( [0] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Jorg Taubel ) ) ) [1] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Dorothée Camilleri ) ) ) [2] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Boaz Mendzelevski ) ) ) [3] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Anne Freier ) ) ) [4] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Christopher S. Spencer ) ) ) [5] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Claus Graff ) ) ) ) [IsPartOfRelationships] => Array ( [0] => Array ( [BibEntity] => Array ( [Dates] => Array ( [0] => Array ( [D] => 15 [M] => 03 [Type] => published [Y] => 2021 ) ) [Identifiers] => Array ( [0] => Array ( [Type] => issn-print [Value] => 1542474X ) [1] => Array ( [Type] => issn-locals [Value] => edsair ) [2] => Array ( [Type] => issn-locals [Value] => edsairFT ) ) [Numbering] => Array ( [0] => Array ( [Type] => volume [Value] => 26 ) [1] => Array ( [Type] => issue [Value] => 5 ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc [Type] => main ) ) ) ) ) ) )
IllustrationInfo