أعرض في EDS

Use of aminoguanidine, a selective inducible nitric oxide synthase inhibitor, to evaluate the role of nitric oxide in periapical inflammation

التفاصيل البيبلوغرافية
العنوان: Use of aminoguanidine, a selective inducible nitric oxide synthase inhibitor, to evaluate the role of nitric oxide in periapical inflammation
المؤلفون: Sanaz Jahadi, Ali R. Farhad, Masoud Saatchi, Seyedmohammad Razavi
المصدر: Journal of Oral Science. 53:225-230
بيانات النشر: Nihon University School of Dentistry, 2011.
سنة النشر: 2011
مصطلحات موضوعية: Cuspid, Pathology, medicine.medical_specialty, Periodontal Ligament, Premedication, medicine.medical_treatment, Pulpectomy, Alveolar Bone Loss, Nitric Oxide Synthase Type II, Inflammation, Periapical inflammation, Pharmacology, Nitric Oxide, Oral cavity, Guanidines, Nitric oxide, chemistry.chemical_compound, Tooth Apex, Alveolar Process, medicine, Animals, Dental Pulp Exposure, General Dentistry, Saline, Dental Cementum, CATS, biology, business.industry, Fibroblasts, Nitric oxide synthase, stomatognathic diseases, chemistry, Cats, Granulation Tissue, biology.protein, Pulp (tooth), Dental Pulp Cavity, medicine.symptom, business, Injections, Intraperitoneal, Periapical Periodontitis
الوصف: The purpose of this study was to evaluate the effects of aminoguanidine (AG) as a selective inhibitor of inducible nitric oxide synthase (iNOS) on the degree of inflammatory response in periapical lesions in the canine teeth of cats. Root canals from 52 cat canine teeth were exposed to the oral cavity and sealed after 7 days. One day before pulp exposure, cats were administered either AG (experimental group) or normal saline (control group), which was continued on a daily basis until the day of sacrifice. Animals were sacrificed at 28 days after pulp exposure. Inflammatory response in the periapical zones was analyzed histologically. The degree of periapical inflammation in the AG group was significantly lower than that in the control group (P < 0.05). Selective iNOS inhibitors such as AG thus reduce the intensity of inflammatory responses in periapical lesions. (J Oral Sci 53, 225- 230, 2011)
تدمد: 1880-4926
1343-4934
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1669a1d1acb418ebf4337f73af9015Test
https://doi.org/10.2334/josnusd.53.225Test
حقوق: OPEN
رقم الانضمام: edsair.doi.dedup.....1e1669a1d1acb418ebf4337f73af9015
قاعدة البيانات: OpenAIRE
ResultId 1
Header edsair
OpenAIRE
edsair.doi.dedup.....1e1669a1d1acb418ebf4337f73af9015
795
3

unknown
794.654296875
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsair&AN=edsair.doi.dedup.....1e1669a1d1acb418ebf4337f73af9015&custid=s6537998&authtype=sso
FullText Array ( [Availability] => 0 )
Items Array ( [Name] => Title [Label] => Title [Group] => Ti [Data] => Use of aminoguanidine, a selective inducible nitric oxide synthase inhibitor, to evaluate the role of nitric oxide in periapical inflammation )
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Sanaz+Jahadi%22&quot;&gt;Sanaz Jahadi&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ali+R%2E+Farhad%22&quot;&gt;Ali R. Farhad&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Masoud+Saatchi%22&quot;&gt;Masoud Saatchi&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Seyedmohammad+Razavi%22&quot;&gt;Seyedmohammad Razavi&lt;/searchLink&gt; )
Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => &lt;i&gt;Journal of Oral Science&lt;/i&gt;. 53:225-230 )
Array ( [Name] => Publisher [Label] => Publisher Information [Group] => PubInfo [Data] => Nihon University School of Dentistry, 2011. )
Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2011 )
Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cuspid%22&quot;&gt;Cuspid&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Pathology%22&quot;&gt;Pathology&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22medicine%2Emedical%5Fspecialty%22&quot;&gt;medicine.medical_specialty&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Periodontal+Ligament%22&quot;&gt;Periodontal Ligament&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Premedication%22&quot;&gt;Premedication&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22medicine%2Emedical%5Ftreatment%22&quot;&gt;medicine.medical_treatment&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Pulpectomy%22&quot;&gt;Pulpectomy&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Alveolar+Bone+Loss%22&quot;&gt;Alveolar Bone Loss&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Nitric+Oxide+Synthase+Type+II%22&quot;&gt;Nitric Oxide Synthase Type II&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Inflammation%22&quot;&gt;Inflammation&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Periapical+inflammation%22&quot;&gt;Periapical inflammation&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Pharmacology%22&quot;&gt;Pharmacology&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Nitric+Oxide%22&quot;&gt;Nitric Oxide&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Oral+cavity%22&quot;&gt;Oral cavity&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Guanidines%22&quot;&gt;Guanidines&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Nitric+oxide%22&quot;&gt;Nitric oxide&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22chemistry%2Echemical%5Fcompound%22&quot;&gt;chemistry.chemical_compound&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Tooth+Apex%22&quot;&gt;Tooth Apex&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Alveolar+Process%22&quot;&gt;Alveolar Process&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22medicine%22&quot;&gt;medicine&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Animals%22&quot;&gt;Animals&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Dental+Pulp+Exposure%22&quot;&gt;Dental Pulp Exposure&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22General+Dentistry%22&quot;&gt;General Dentistry&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Saline%22&quot;&gt;Saline&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Dental+Cementum%22&quot;&gt;Dental Cementum&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22CATS%22&quot;&gt;CATS&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22biology%22&quot;&gt;biology&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22business%2Eindustry%22&quot;&gt;business.industry&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Fibroblasts%22&quot;&gt;Fibroblasts&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Nitric+oxide+synthase%22&quot;&gt;Nitric oxide synthase&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22stomatognathic+diseases%22&quot;&gt;stomatognathic diseases&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22chemistry%22&quot;&gt;chemistry&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cats%22&quot;&gt;Cats&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Granulation+Tissue%22&quot;&gt;Granulation Tissue&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22biology%2Eprotein%22&quot;&gt;biology.protein&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Pulp+%28tooth%29%22&quot;&gt;Pulp (tooth)&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Dental+Pulp+Cavity%22&quot;&gt;Dental Pulp Cavity&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22medicine%2Esymptom%22&quot;&gt;medicine.symptom&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22business%22&quot;&gt;business&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Injections%2C+Intraperitoneal%22&quot;&gt;Injections, Intraperitoneal&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Periapical+Periodontitis%22&quot;&gt;Periapical Periodontitis&lt;/searchLink&gt; )
Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => The purpose of this study was to evaluate the effects of aminoguanidine (AG) as a selective inhibitor of inducible nitric oxide synthase (iNOS) on the degree of inflammatory response in periapical lesions in the canine teeth of cats. Root canals from 52 cat canine teeth were exposed to the oral cavity and sealed after 7 days. One day before pulp exposure, cats were administered either AG (experimental group) or normal saline (control group), which was continued on a daily basis until the day of sacrifice. Animals were sacrificed at 28 days after pulp exposure. Inflammatory response in the periapical zones was analyzed histologically. The degree of periapical inflammation in the AG group was significantly lower than that in the control group (P &lt; 0.05). Selective iNOS inhibitors such as AG thus reduce the intensity of inflammatory responses in periapical lesions. (J Oral Sci 53, 225- 230, 2011) )
Array ( [Name] => ISSN [Label] => ISSN [Group] => ISSN [Data] => 1880-4926&lt;br /&gt;1343-4934 )
Array ( [Name] => URL [Label] => Access URL [Group] => URL [Data] => &lt;link linkTarget=&quot;URL&quot; linkTerm=&quot;https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1669a1d1acb418ebf4337f73af9015&quot; linkWindow=&quot;_blank&quot;&gt;https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1669a1d1acb418ebf4337f73af9015&lt;/link&gt;&lt;br /&gt;&lt;link linkTarget=&quot;URL&quot; linkTerm=&quot;https://doi.org/10.2334/josnusd.53.225&quot; linkWindow=&quot;_blank&quot;&gt;https://doi.org/10.2334/josnusd.53.225&lt;/link&gt; )
Array ( [Name] => Copyright [Label] => Rights [Group] => Cpyrght [Data] => OPEN )
Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsair.doi.dedup.....1e1669a1d1acb418ebf4337f73af9015 )
RecordInfo Array ( [BibEntity] => Array ( [Languages] => Array ( [0] => Array ( [Text] => Undetermined ) ) [PhysicalDescription] => Array ( [Pagination] => Array ( [PageCount] => 6 [StartPage] => 225 ) ) [Subjects] => Array ( [0] => Array ( [SubjectFull] => Cuspid [Type] => general ) [1] => Array ( [SubjectFull] => Pathology [Type] => general ) [2] => Array ( [SubjectFull] => medicine.medical_specialty [Type] => general ) [3] => Array ( [SubjectFull] => Periodontal Ligament [Type] => general ) [4] => Array ( [SubjectFull] => Premedication [Type] => general ) [5] => Array ( [SubjectFull] => medicine.medical_treatment [Type] => general ) [6] => Array ( [SubjectFull] => Pulpectomy [Type] => general ) [7] => Array ( [SubjectFull] => Alveolar Bone Loss [Type] => general ) [8] => Array ( [SubjectFull] => Nitric Oxide Synthase Type II [Type] => general ) [9] => Array ( [SubjectFull] => Inflammation [Type] => general ) [10] => Array ( [SubjectFull] => Periapical inflammation [Type] => general ) [11] => Array ( [SubjectFull] => Pharmacology [Type] => general ) [12] => Array ( [SubjectFull] => Nitric Oxide [Type] => general ) [13] => Array ( [SubjectFull] => Oral cavity [Type] => general ) [14] => Array ( [SubjectFull] => Guanidines [Type] => general ) [15] => Array ( [SubjectFull] => Nitric oxide [Type] => general ) [16] => Array ( [SubjectFull] => chemistry.chemical_compound [Type] => general ) [17] => Array ( [SubjectFull] => Tooth Apex [Type] => general ) [18] => Array ( [SubjectFull] => Alveolar Process [Type] => general ) [19] => Array ( [SubjectFull] => medicine [Type] => general ) [20] => Array ( [SubjectFull] => Animals [Type] => general ) [21] => Array ( [SubjectFull] => Dental Pulp Exposure [Type] => general ) [22] => Array ( [SubjectFull] => General Dentistry [Type] => general ) [23] => Array ( [SubjectFull] => Saline [Type] => general ) [24] => Array ( [SubjectFull] => Dental Cementum [Type] => general ) [25] => Array ( [SubjectFull] => CATS [Type] => general ) [26] => Array ( [SubjectFull] => biology [Type] => general ) [27] => Array ( [SubjectFull] => business.industry [Type] => general ) [28] => Array ( [SubjectFull] => Fibroblasts [Type] => general ) [29] => Array ( [SubjectFull] => Nitric oxide synthase [Type] => general ) [30] => Array ( [SubjectFull] => stomatognathic diseases [Type] => general ) [31] => Array ( [SubjectFull] => chemistry [Type] => general ) [32] => Array ( [SubjectFull] => Cats [Type] => general ) [33] => Array ( [SubjectFull] => Granulation Tissue [Type] => general ) [34] => Array ( [SubjectFull] => biology.protein [Type] => general ) [35] => Array ( [SubjectFull] => Pulp (tooth) [Type] => general ) [36] => Array ( [SubjectFull] => Dental Pulp Cavity [Type] => general ) [37] => Array ( [SubjectFull] => medicine.symptom [Type] => general ) [38] => Array ( [SubjectFull] => business [Type] => general ) [39] => Array ( [SubjectFull] => Injections, Intraperitoneal [Type] => general ) [40] => Array ( [SubjectFull] => Periapical Periodontitis [Type] => general ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Use of aminoguanidine, a selective inducible nitric oxide synthase inhibitor, to evaluate the role of nitric oxide in periapical inflammation [Type] => main ) ) ) [BibRelationships] => Array ( [HasContributorRelationships] => Array ( [0] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Sanaz Jahadi ) ) ) [1] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Ali R. Farhad ) ) ) [2] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Masoud Saatchi ) ) ) [3] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Seyedmohammad Razavi ) ) ) ) [IsPartOfRelationships] => Array ( [0] => Array ( [BibEntity] => Array ( [Dates] => Array ( [0] => Array ( [D] => 01 [M] => 01 [Type] => published [Y] => 2011 ) ) [Identifiers] => Array ( [0] => Array ( [Type] => issn-print [Value] => 18804926 ) [1] => Array ( [Type] => issn-print [Value] => 13434934 ) [2] => Array ( [Type] => issn-locals [Value] => edsair ) [3] => Array ( [Type] => issn-locals [Value] => edsairFT ) ) [Numbering] => Array ( [0] => Array ( [Type] => volume [Value] => 53 ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Journal of Oral Science [Type] => main ) ) ) ) ) ) )
IllustrationInfo