Hypoglycemia Is Independently Associated with Multidimensional Impairment in Elderly Diabetic Patients
العنوان: | Hypoglycemia Is Independently Associated with Multidimensional Impairment in Elderly Diabetic Patients |
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المؤلفون: | Antonio Tiengo, Andrea Pilotto, Stefania Maggi, Giuseppe Rengo, Filomena Addante, Gaetano Crepaldi, P Cavallo Perin, Marianna Noale |
المساهمون: | Pilotto, A., Noale, M., Maggi, S., Addante, F., Tiengo, A., Perin, P. C., Rengo, G., Crepaldi, Anna |
المصدر: | BioMed Research International BioMed Research International, Vol 2014 (2014) |
بيانات النشر: | Hindawi Publishing Corporation, 2014. |
سنة النشر: | 2014 |
مصطلحات موضوعية: | Gerontology, Male, medicine.medical_specialty, Article Subject, lcsh:Medicine, Hypoglycemia, General Biochemistry, Genetics and Molecular Biology, Risk Factors, Internal medicine, Diabetes mellitus, Medicine, Humans, Decompensation, Geriatric Assessment, Glycemic, Aged, Demography, General Immunology and Microbiology, business.industry, Risk Factor, lcsh:R, Type 2 Diabetes Mellitus, General Medicine, medicine.disease, Comorbidity, Diabetes Mellitus, Type 2, Cohort, Population study, Female, business, Human, Research Article |
الوصف: | Aim. To identify the characteristics associated with multidimensional impairment, evaluated through the Multidimensional Prognostic Index (MPI), a validated predictive tool for mortality derived from a standardized Comprehensive Geriatric Assessment (CGA), in a cohort of elderly diabetic patients treated with oral hypoglycemic drugs.Methods and Results. The study population consisted of 1342 diabetic patients consecutively enrolled in 57 diabetes centers distributed throughout Italy, within the Metabolic Study. Inclusion criteria were diagnosis of type 2 diabetes mellitus (DM), 65 years old or over, and treatment with oral antidiabetic medications. Data concerning DM duration, medications for DM taken during the 3-month period before inclusion in the study, number of hypoglycemic events, and complications of DM were collected. Multidimensional impairment was assessed using the MPI evaluating functional, cognitive, and nutritional status; risk of pressure sores; comorbidity; number of drugs taken; and cohabitation status. The mean age of participants was 73.3 ± 5.5 years, and the mean MPI score was 0.22 ± 0.13. Multivariate analysis showed that advanced age, female gender, hypoglycemic events, and hospitalization for glycemic decompensation were independently associated with a worse MPI score.Conclusion. Stratification of elderly diabetic patients using the MPI might help to identify those patients at highest risk who need better-tailored treatment. |
وصف الملف: | text/xhtml |
اللغة: | English |
تدمد: | 2314-6133 |
DOI: | 10.1155/2014/906103 |
الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03da7e28c94560bd7f18813238ad44d6Test |
حقوق: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....03da7e28c94560bd7f18813238ad44d6 |
قاعدة البيانات: | OpenAIRE |