Synergistic effect of thrombin and CD40 ligand on endothelial matrix metalloproteinase-10 expression and microparticle generation in vitro and in vivo
| ResultId |
1 |
|---|---|
| Header |
edsair OpenAIRE edsair.RECOLECTA.....7f45a90978813580b62bcfba5af24c36 771 3 unknown 770.984252929688 |
| PLink |
https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsair&AN=edsair.RECOLECTA.....7f45a90978813580b62bcfba5af24c36&custid=s6537998&authtype=sso |
| FullText |
Array
(
[Availability] => 0
)
|
| Items |
Array
(
[Name] => Title
[Label] => Title
[Group] => Ti
[Data] => Synergistic effect of thrombin and CD40 ligand on endothelial matrix metalloproteinase-10 expression and microparticle generation in vitro and in vivo
)
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22De+Lizarrondo+S%2EM%2E%22">De Lizarrondo S.M.</searchLink><br /><searchLink fieldCode="AR" term="%22Roncal+C%2E%22">Roncal C.</searchLink><br /><searchLink fieldCode="AR" term="%22Calvayrac+O%2E%22">Calvayrac O.</searchLink><br /><searchLink fieldCode="AR" term="%22Rodríguez+C%2E%22">Rodríguez C.</searchLink><br /><searchLink fieldCode="AR" term="%22Varo+N%2E%22">Varo N.</searchLink><br /><searchLink fieldCode="AR" term="%22Purroy+A%2E%22">Purroy A.</searchLink><br /><searchLink fieldCode="AR" term="%22Lorente+L%2E%22">Lorente L.</searchLink><br /><searchLink fieldCode="AR" term="%22Rodríguez+J%2EA%2E%22">Rodríguez J.A.</searchLink><br /><searchLink fieldCode="AR" term="%22Doeuvre+L%2E%22">Doeuvre L.</searchLink><br /><searchLink fieldCode="AR" term="%22Hervás-Stubbs+S%2E%22">Hervás-Stubbs S.</searchLink><br /><searchLink fieldCode="AR" term="%22Angles-Cano+E%2E%22">Angles-Cano E.</searchLink><br /><searchLink fieldCode="AR" term="%22Páramo+J%2EA%2E%22">Páramo J.A.</searchLink><br /><searchLink fieldCode="AR" term="%22Martínez-González+J%2E%22">Martínez-González J.</searchLink><br /><searchLink fieldCode="AR" term="%22Orbe+J%2E%22">Orbe J.</searchLink> ) Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY<br />r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau<br />instname ) Array ( [Name] => Publisher [Label] => Publisher Information [Group] => PubInfo [Data] => LIPPINCOTT WILLIAMS & WILKINS, 2012. ) Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2012 ) Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => <searchLink fieldCode="DE" term="%22mitogen+activated+protein+kinase+p38%22">mitogen activated protein kinase p38</searchLink><br /><searchLink fieldCode="DE" term="%22Lipopolysaccharides%22">Lipopolysaccharides</searchLink><br /><searchLink fieldCode="DE" term="%22Male%22">Male</searchLink><br /><searchLink fieldCode="DE" term="%22Mice%22">Mice</searchLink><br /><searchLink fieldCode="DE" term="%22Antigens%2C+CD40%22">Antigens, CD40</searchLink><br /><searchLink fieldCode="DE" term="%22Cell-Derived+Microparticles%22">Cell-Derived Microparticles</searchLink><br /><searchLink fieldCode="DE" term="%22stress+activated+protein+kinase+1%22">stress activated protein kinase 1</searchLink><br /><searchLink fieldCode="DE" term="%22endothelium+cell%22">endothelium cell</searchLink><br /><searchLink fieldCode="DE" term="%22Cells%2C+Cultured%22">Cells, Cultured</searchLink><br /><searchLink fieldCode="DE" term="%22Aged%2C+80+and+over%22">Aged, 80 and over</searchLink><br /><searchLink fieldCode="DE" term="%22Mice%2C+Knockout%22">Mice, Knockout</searchLink><br /><searchLink fieldCode="DE" term="%22messenger+RNA%22">messenger RNA</searchLink><br /><searchLink fieldCode="DE" term="%22lipopolysaccharide%22">lipopolysaccharide</searchLink><br /><searchLink fieldCode="DE" term="%22proteinase+activated+receptor+1%22">proteinase activated receptor 1</searchLink><br /><searchLink fieldCode="DE" term="%22article%22">article</searchLink><br /><searchLink fieldCode="DE" term="%22Hirudins%22">Hirudins</searchLink><br /><searchLink fieldCode="DE" term="%22Middle+Aged%22">Middle Aged</searchLink><br /><searchLink fieldCode="DE" term="%22thrombin%22">thrombin</searchLink><br /><searchLink fieldCode="DE" term="%22priority+journal%22">priority journal</searchLink><br /><searchLink fieldCode="DE" term="%22Female%22">Female</searchLink><br /><searchLink fieldCode="DE" term="%22CD40+ligand%22">CD40 ligand</searchLink><br /><searchLink fieldCode="DE" term="%22Adult%22">Adult</searchLink><br /><searchLink fieldCode="DE" term="%22in+vitro+study%22">in vitro study</searchLink><br /><searchLink fieldCode="DE" term="%22animal+experiment%22">animal experiment</searchLink><br /><searchLink fieldCode="DE" term="%22Antibodies%22">Antibodies</searchLink><br /><searchLink fieldCode="DE" term="%22Gene+Expression+Regulation%2C+Enzymologic%22">Gene Expression Regulation, Enzymologic</searchLink><br /><searchLink fieldCode="DE" term="%22in+vivo+study%22">in vivo study</searchLink><br /><searchLink fieldCode="DE" term="%22Matrix+Metalloproteinase+10%22">Matrix Metalloproteinase 10</searchLink><br /><searchLink fieldCode="DE" term="%22Human+Umbilical+Vein+Endothelial+Cells%22">Human Umbilical Vein Endothelial Cells</searchLink><br /><searchLink fieldCode="DE" term="%22hirudin%22">hirudin</searchLink><br /><searchLink fieldCode="DE" term="%22Animals%22">Animals</searchLink><br /><searchLink fieldCode="DE" term="%22Humans%22">Humans</searchLink><br /><searchLink fieldCode="DE" term="%22controlled+study%22">controlled study</searchLink><br /><searchLink fieldCode="DE" term="%22Mitogen-Activated+Protein+Kinase+8%22">Mitogen-Activated Protein Kinase 8</searchLink><br /><searchLink fieldCode="DE" term="%22human%22">human</searchLink><br /><searchLink fieldCode="DE" term="%22protein+expression%22">protein expression</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+Coagulation%22">Blood Coagulation</searchLink><br /><searchLink fieldCode="DE" term="%22mouse%22">mouse</searchLink><br /><searchLink fieldCode="DE" term="%22thrombosis%22">thrombosis</searchLink><br /><searchLink fieldCode="DE" term="%22endothelial+microparticle%22">endothelial microparticle</searchLink><br /><searchLink fieldCode="DE" term="%22Aged%22">Aged</searchLink><br /><searchLink fieldCode="DE" term="%22nonhuman%22">nonhuman</searchLink><br /><searchLink fieldCode="DE" term="%22animal+model%22">animal model</searchLink><br /><searchLink fieldCode="DE" term="%22human+cell%22">human cell</searchLink><br /><searchLink fieldCode="DE" term="%22Endothelial+Cells%22">Endothelial Cells</searchLink><br /><searchLink fieldCode="DE" term="%22Disseminated+Intravascular+Coagulation%22">Disseminated Intravascular Coagulation</searchLink><br /><searchLink fieldCode="DE" term="%22major+clinical+study%22">major clinical study</searchLink><br /><searchLink fieldCode="DE" term="%22human+tissue%22">human tissue</searchLink><br /><searchLink fieldCode="DE" term="%22Endotoxemia%22">Endotoxemia</searchLink><br /><searchLink fieldCode="DE" term="%22p38+Mi%22">p38 Mi</searchLink><br /><searchLink fieldCode="DE" term="%22Mice%2C+Inbred+C57BL%22">Mice, Inbred C57BL</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+Models%2C+Animal%22">Disease Models, Animal</searchLink><br /><searchLink fieldCode="DE" term="%22Case-Control+Studies%22">Case-Control Studies</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+Analysis%22">Multivariate Analysis</searchLink><br /><searchLink fieldCode="DE" term="%22stromelysin+2%22">stromelysin 2</searchLink> ) Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => Objective-Thrombin induces CD40 ligand (CD40L) and matrix metalloproteinases (MMPs) under inflammatory/prothrombotic conditions. Thrombin and CD40L could modulate endothelial MMP-10 expression in vitro and in vivo. Methods and Results-Human endothelial cells were stimulated with thrombin (0.1-10 U/mL), CD40L (0.25-1 µg/mL), or their combination (thrombin/CD40L) to assess MMP-10 expression and microparticle generation. Thrombin/CD40L elicited higher MMP-10 mRNA (5-fold; P ) Array ( [Name] => ISSN [Label] => ISSN [Group] => ISSN [Data] => 1079-5642 ) Array ( [Name] => URL [Label] => Access URL [Group] => URL [Data] => <link linkTarget="URL" linkTerm="https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::7f45a90978813580b62bcfba5af24c36" linkWindow="_blank">https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::7f45a90978813580b62bcfba5af24c36</link><br /><link linkTarget="URL" linkTerm="https://www.scopus.com/inward/record.uri?eid=2-s2.0-84861529113&doi=10.1161/ATVBAHA.112.248773&partnerID=40&md5=b2c680a78119daa02281671ac1b2415d" linkWindow="_blank">https://www.scopus.com/inward/record.uri?eid=2-s2.0-84861529113&doi=10.1161/ATVBAHA.112.248773&partnerID=40&md5=b2c680a78119daa02281671ac1b2415d</link> ) Array ( [Name] => Copyright [Label] => Rights [Group] => Cpyrght [Data] => OPEN ) Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsair.RECOLECTA.....7f45a90978813580b62bcfba5af24c36 ) |
| RecordInfo |
Array
(
[BibEntity] => Array
(
[Languages] => Array
(
[0] => Array
(
[Text] => Undetermined
)
)
[Subjects] => Array
(
[0] => Array
(
[SubjectFull] => mitogen activated protein kinase p38
[Type] => general
)
[1] => Array
(
[SubjectFull] => Lipopolysaccharides
[Type] => general
)
[2] => Array
(
[SubjectFull] => Male
[Type] => general
)
[3] => Array
(
[SubjectFull] => Mice
[Type] => general
)
[4] => Array
(
[SubjectFull] => Antigens, CD40
[Type] => general
)
[5] => Array
(
[SubjectFull] => Cell-Derived Microparticles
[Type] => general
)
[6] => Array
(
[SubjectFull] => stress activated protein kinase 1
[Type] => general
)
[7] => Array
(
[SubjectFull] => endothelium cell
[Type] => general
)
[8] => Array
(
[SubjectFull] => Cells, Cultured
[Type] => general
)
[9] => Array
(
[SubjectFull] => Aged, 80 and over
[Type] => general
)
[10] => Array
(
[SubjectFull] => Mice, Knockout
[Type] => general
)
[11] => Array
(
[SubjectFull] => messenger RNA
[Type] => general
)
[12] => Array
(
[SubjectFull] => lipopolysaccharide
[Type] => general
)
[13] => Array
(
[SubjectFull] => proteinase activated receptor 1
[Type] => general
)
[14] => Array
(
[SubjectFull] => article
[Type] => general
)
[15] => Array
(
[SubjectFull] => Hirudins
[Type] => general
)
[16] => Array
(
[SubjectFull] => Middle Aged
[Type] => general
)
[17] => Array
(
[SubjectFull] => thrombin
[Type] => general
)
[18] => Array
(
[SubjectFull] => priority journal
[Type] => general
)
[19] => Array
(
[SubjectFull] => Female
[Type] => general
)
[20] => Array
(
[SubjectFull] => CD40 ligand
[Type] => general
)
[21] => Array
(
[SubjectFull] => Adult
[Type] => general
)
[22] => Array
(
[SubjectFull] => in vitro study
[Type] => general
)
[23] => Array
(
[SubjectFull] => animal experiment
[Type] => general
)
[24] => Array
(
[SubjectFull] => Antibodies
[Type] => general
)
[25] => Array
(
[SubjectFull] => Gene Expression Regulation, Enzymologic
[Type] => general
)
[26] => Array
(
[SubjectFull] => in vivo study
[Type] => general
)
[27] => Array
(
[SubjectFull] => Matrix Metalloproteinase 10
[Type] => general
)
[28] => Array
(
[SubjectFull] => Human Umbilical Vein Endothelial Cells
[Type] => general
)
[29] => Array
(
[SubjectFull] => hirudin
[Type] => general
)
[30] => Array
(
[SubjectFull] => Animals
[Type] => general
)
[31] => Array
(
[SubjectFull] => Humans
[Type] => general
)
[32] => Array
(
[SubjectFull] => controlled study
[Type] => general
)
[33] => Array
(
[SubjectFull] => Mitogen-Activated Protein Kinase 8
[Type] => general
)
[34] => Array
(
[SubjectFull] => human
[Type] => general
)
[35] => Array
(
[SubjectFull] => protein expression
[Type] => general
)
[36] => Array
(
[SubjectFull] => Blood Coagulation
[Type] => general
)
[37] => Array
(
[SubjectFull] => mouse
[Type] => general
)
[38] => Array
(
[SubjectFull] => thrombosis
[Type] => general
)
[39] => Array
(
[SubjectFull] => endothelial microparticle
[Type] => general
)
[40] => Array
(
[SubjectFull] => Aged
[Type] => general
)
[41] => Array
(
[SubjectFull] => nonhuman
[Type] => general
)
[42] => Array
(
[SubjectFull] => animal model
[Type] => general
)
[43] => Array
(
[SubjectFull] => human cell
[Type] => general
)
[44] => Array
(
[SubjectFull] => Endothelial Cells
[Type] => general
)
[45] => Array
(
[SubjectFull] => Disseminated Intravascular Coagulation
[Type] => general
)
[46] => Array
(
[SubjectFull] => major clinical study
[Type] => general
)
[47] => Array
(
[SubjectFull] => human tissue
[Type] => general
)
[48] => Array
(
[SubjectFull] => Endotoxemia
[Type] => general
)
[49] => Array
(
[SubjectFull] => p38 Mi
[Type] => general
)
[50] => Array
(
[SubjectFull] => Mice, Inbred C57BL
[Type] => general
)
[51] => Array
(
[SubjectFull] => Disease Models, Animal
[Type] => general
)
[52] => Array
(
[SubjectFull] => Case-Control Studies
[Type] => general
)
[53] => Array
(
[SubjectFull] => Multivariate Analysis
[Type] => general
)
[54] => Array
(
[SubjectFull] => stromelysin 2
[Type] => general
)
)
[Titles] => Array
(
[0] => Array
(
[TitleFull] => Synergistic effect of thrombin and CD40 ligand on endothelial matrix metalloproteinase-10 expression and microparticle generation in vitro and in vivo
[Type] => main
)
)
)
[BibRelationships] => Array
(
[HasContributorRelationships] => Array
(
[0] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => De Lizarrondo S.M.
)
)
)
[1] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Roncal C.
)
)
)
[2] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Calvayrac O.
)
)
)
[3] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Rodríguez C.
)
)
)
[4] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Varo N.
)
)
)
[5] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Purroy A.
)
)
)
[6] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Lorente L.
)
)
)
[7] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Rodríguez J.A.
)
)
)
[8] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Doeuvre L.
)
)
)
[9] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Hervás-Stubbs S.
)
)
)
[10] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Angles-Cano E.
)
)
)
[11] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Páramo J.A.
)
)
)
[12] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Martínez-González J.
)
)
)
[13] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Orbe J.
)
)
)
)
[IsPartOfRelationships] => Array
(
[0] => Array
(
[BibEntity] => Array
(
[Dates] => Array
(
[0] => Array
(
[D] => 01
[M] => 01
[Type] => published
[Y] => 2012
)
)
[Identifiers] => Array
(
[0] => Array
(
[Type] => issn-print
[Value] => 10795642
)
[1] => Array
(
[Type] => issn-locals
[Value] => edsair
)
[2] => Array
(
[Type] => issn-locals
[Value] => edsairFT
)
)
)
)
)
)
)
|
| IllustrationInfo |