دورية أكاديمية
Severe Community-Acquired Pneumonia in Immunocompromised Patients.
| العنوان: | Severe Community-Acquired Pneumonia in Immunocompromised Patients. |
|---|---|
| المؤلفون: | Chean, Dara, Windsor, Camille, Lafarge, Antoine, Dupont, Thibault, Nakaa, Sabrine, Whiting, Livia, Joseph, Adrien, Lemiale, Virginie, Azoulay, Elie |
| المصدر: | Seminars in Respiratory & Critical Care Medicine; Apr2024, Vol. 45 Issue 2, p255-265, 11p |
| مصطلحات موضوعية: | COMMUNITY-acquired pneumonia, IMMUNOCOMPROMISED patients, ADULT respiratory distress syndrome, HOSPITAL mortality, INTENSIVE care units, MUCOCUTANEOUS lymph node syndrome, PNEUMOCYSTIS jiroveci |
| مستخلص: | Due to higher survival rates with good quality of life, related to new treatments in the fields of oncology, hematology, and transplantation, the number of immunocompromised patients is increasing. But these patients are at high risk of intensive care unit admission because of numerous complications. Acute respiratory failure due to severe community-acquired pneumonia is one of the leading causes of admission. In this setting, the need for invasive mechanical ventilation is up to 60%, associated with a high hospital mortality rate of around 40 to 50%. A wide range of pathogens according to the reason of immunosuppression is associated with severe pneumonia in those patients: documented bacterial pneumonia represents a third of cases, viral and fungal pneumonia both account for up to 15% of cases. For patients with an undetermined etiology despite comprehensive diagnostic workup, the hospital mortality rate is very high. Thus, a standardized diagnosis strategy should be defined to increase the diagnosis rate and prescribe the appropriate treatment. This review focuses on the benefit-to-risk ratio of invasive or noninvasive strategies, in the era of omics, for the management of critically ill immunocompromised patients with severe pneumonia in terms of diagnosis and oxygenation. [ABSTRACT FROM AUTHOR] |
| Copyright of Seminars in Respiratory & Critical Care Medicine is the property of Thieme Medical Publishing Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| قاعدة البيانات: | Complementary Index |
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