دورية أكاديمية

Neurocysticercosis Diagnosis in a Non-Endemic Country: France.

التفاصيل البيبلوغرافية
العنوان: Neurocysticercosis Diagnosis in a Non-Endemic Country: France.
المؤلفون: Zemmour, Ines, Durieux, Marie-Fleur, Herault, Etienne, Rouges, Célia, Šoba, Barbara, Mercier, Aurélien, Ariey, Frédéric, Preux, Pierre-Marie, Yera, Hélène
المصدر: Pathogens; Oct2023, Vol. 12 Issue 10, p1205, 11p
مصطلحات موضوعية: NEUROCYSTICERCOSIS, DIAGNOSTIC use of polymerase chain reaction, SYMPTOMS, DIAGNOSIS, BRAIN damage
مصطلحات جغرافية: FRANCE
مستخلص: Diagnosing neurocysticercosis (NCC) is difficult due to its variable clinical presentations and the different imaging techniques used to detect brain damage. This study aimed to evaluate the use of cerebrospinal fluid serology and PCR for diagnosing biological neurocysticercosis in a non-endemic country. We tested samples from patients living in France with suspected NCC and confirmed that 45 of the patients presented with the disease. A total of 89% of patients had previously traveled to countries where the disease was endemic. The sensitivity of Western blots compared to ELISA was not significantly different (80% vs. 60%) (p > 0.05), and neither was the sensitivity of Western blots vs. PCR (78% vs. 56%) (p > 0.05). The PCR sensitivity was 78% and 47% in definitive NCC and in probable NCC. PCR tests using cerebrospinal fluid should be considered as a diagnostic criterion for identifying NCC. [ABSTRACT FROM AUTHOR]
Copyright of Pathogens is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
قاعدة البيانات: Complementary Index
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