دورية أكاديمية
Comparison of multiparametric magnetic resonance imaging sequences with laboratory parameters for prognosticating renal function in chronic kidney disease.
| العنوان: | Comparison of multiparametric magnetic resonance imaging sequences with laboratory parameters for prognosticating renal function in chronic kidney disease. |
|---|---|
| المؤلفون: | Inoue, Tsutomu, Kozawa, Eito, Ishikawa, Masahiro, Fukaya, Daichi, Amano, Hiroaki, Watanabe, Yusuke, Tomori, Koji, Kobayashi, Naoki, Niitsu, Mamoru, Okada, Hirokazu |
| المصدر: | Scientific Reports; 11/11/2021, Vol. 11 Issue 1, p1-9, 9p |
| مصطلحات موضوعية: | MAGNETIC resonance imaging, DIFFUSION magnetic resonance imaging, DIFFUSION tensor imaging, CHRONIC kidney failure, KIDNEY physiology, PROGNOSIS, DIFFUSION coefficients, RECEIVER operating characteristic curves |
| مستخلص: | Magnetic resonance imaging (MRI) is playing an increasingly important role in evaluating chronic kidney disease (CKD). It has the potential to be used not only for evaluation of physiological and pathological states, but also for prediction of disease course. Although different MRI sequences have been employed in renal disease, there are few studies that have compared the different sequences. We compared several multiparametric MRI sequences, and compared their results with the estimated glomerular filtration rate. Principal component analysis showed a similarity between T1 values and tissue perfusion (arterial spin labelling), and between fractional anisotropy (diffusion tensor imaging) and apparent diffusion coefficient values (diffusion-weighted imaging). In multiple regression analysis, only T2* values, derived from the blood oxygenation level-dependent (BOLD) MRI sequence, were associated with estimated glomerular filtration rate slope after adjusting for degree of proteinuria, a classic prognostic factor for CKD. In receiver operating characteristic curve analysis, T2* values were a good predictor of rapid deterioration, regardless of the degree of proteinuria. This suggests further study of the use of BOLD-derived T2* values in the workup of CKD, especially to predict the disease course. [ABSTRACT FROM AUTHOR] |
| Copyright of Scientific Reports is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| قاعدة البيانات: | Complementary Index |
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