دورية أكاديمية
Clinical significance of post‐prophylaxis cytomegalovirus infection in lung transplant recipients.
العنوان: | Clinical significance of post‐prophylaxis cytomegalovirus infection in lung transplant recipients. |
---|---|
المؤلفون: | Jaamei, Nikta, Koutsokera, Angela, Pasquier, Jérôme, Mombelli, Matteo, Meylan, Pascal, Pascual, Manuel, Aubert, John‐David, Manuel, Oriol |
المصدر: | Transplant Infectious Disease; Aug2018, Vol. 20 Issue 4, p1-1, 7p |
مصطلحات موضوعية: | CYTOMEGALOVIRUS diseases, LUNG transplantation, GRAFT rejection, HOMOGRAFTS, ANTIVIRAL agents, PREVENTIVE medicine, FOLLOW-up studies (Medicine), PNEUMONIA, PATIENTS |
مستخلص: | Abstract: Cytomegalovirus (CMV) disease has been associated with the development of chronic lung allograft dysfunction (CLAD) after transplantation. However, the relevance of CMV replication occurring after the discontinuation of antiviral prophylaxis on the development of CLAD has not been fully established. Patients who underwent lung transplantation during 2004‐2014 were included. All patients received antiviral prophylaxis for 3‐6 months, followed by monitoring of CMV replication during the first year post‐transplantation (preemptive therapy). Risk factors for the development of CLAD were assessed by Cox models. A linear regression model with an interaction coefficient between time and CMV infection was used to evaluate the influence of CMV infection on the evolution of FEV |
Copyright of Transplant Infectious Disease is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
قاعدة البيانات: | Complementary Index |