دورية أكاديمية

IgG4-related retroperitoneal fibrosis with acute kidney injury: a case report and literature review.

التفاصيل البيبلوغرافية
العنوان: IgG4-related retroperitoneal fibrosis with acute kidney injury: a case report and literature review.
المؤلفون: Petelytska, Liubov1 (AUTHOR) l.petelytska@gmail.com, Nikitina, Adriana1 (AUTHOR), Tarasenko, Oksana2 (AUTHOR), Chechotenko, Ihor3 (AUTHOR), Mykhailov, Dmytro3 (AUTHOR), Kravchenko, Vladyslav4 (AUTHOR), Iaremenko, Oleg1 (AUTHOR)
المصدر: Rheumatology International. Nov2023, Vol. 43 Issue 11, p2141-2153. 13p.
مصطلحات موضوعية: *ACUTE kidney failure, *RETROPERITONEAL fibrosis, *LITERATURE reviews, *RENAL fibrosis, *SYMPTOMS, *RETROPERITONEUM
مستخلص: IgG4-related retroperitoneal fibrosis is a rare cause of renal dysfunction that usually manifests as obstructive nephropathy (sometimes with extrarenal manifestations). Due to the non-specific symptoms at the onset of the disease and often latent course, special laboratory and instrumental examination methods are usually needed to establish a diagnosis. The article describes a clinical case of a relapse of IgG4-related retroperitoneal fibrosis in a 53-year-old patient, who developed bilateral ureterohydronephrosis with postrenal acute kidney injury after the withdrawal of glucocorticoid therapy. The patient underwent bilateral percutaneous nephrostomy and resumed glucocorticoids at a dose of 30 mg/day. Postobstructive diuresis was 22 L. Treatment resulted in a complete normalization of the creatinine level and transient hypokalemia, which was eliminated with potassium medications. At the final stage of the treatment, bilateral stenting of both ureters was performed with a tapering of glucocorticoids to 5 mg per day with CT control of the retroperitoneal space after 5 months. A clinical case demonstrates that an interruption of glucocorticoid treatment in patients with IgG4-related retroperitoneal fibrosis can lead to ureterohydronephrosis with the development of acute kidney injury. In such cases, stenting of the ureters could be considered an optimal therapeutic option. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
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Array ( [Name] => Abstract [Label] => Abstract [Group] => Ab [Data] => IgG4-related retroperitoneal fibrosis is a rare cause of renal dysfunction that usually manifests as obstructive nephropathy (sometimes with extrarenal manifestations). Due to the non-specific symptoms at the onset of the disease and often latent course, special laboratory and instrumental examination methods are usually needed to establish a diagnosis. The article describes a clinical case of a relapse of IgG4-related retroperitoneal fibrosis in a 53-year-old patient, who developed bilateral ureterohydronephrosis with postrenal acute kidney injury after the withdrawal of glucocorticoid therapy. The patient underwent bilateral percutaneous nephrostomy and resumed glucocorticoids at a dose of 30 mg/day. Postobstructive diuresis was 22 L. Treatment resulted in a complete normalization of the creatinine level and transient hypokalemia, which was eliminated with potassium medications. At the final stage of the treatment, bilateral stenting of both ureters was performed with a tapering of glucocorticoids to 5 mg per day with CT control of the retroperitoneal space after 5 months. A clinical case demonstrates that an interruption of glucocorticoid treatment in patients with IgG4-related retroperitoneal fibrosis can lead to ureterohydronephrosis with the development of acute kidney injury. In such cases, stenting of the ureters could be considered an optimal therapeutic option. [ABSTRACT FROM AUTHOR] )
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