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Outcomes of Transcatheter Aortic Valve Implantation in Nonagenarians Compared to Younger than 90 Year Old Patients.

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العنوان: Outcomes of Transcatheter Aortic Valve Implantation in Nonagenarians Compared to Younger than 90 Year Old Patients.
المؤلفون: Matta, Anthony1,2 (AUTHOR) dr.anthonymatta@hotmail.com, Lhermusier, Thibault1 (AUTHOR), Bouisset, Fréderic1 (AUTHOR), Parada, Francisco-Campelo1 (AUTHOR), ELBaz, Meyer1 (AUTHOR), Nader, Vanessa1 (AUTHOR), Blanco, Stephanie1 (AUTHOR), Roncalli, Jerome1 (AUTHOR), Carrié, Didier1 (AUTHOR)
المصدر: American Journal of Medicine. Jun2022, Vol. 135 Issue 6, p745-751. 7p.
مصطلحات موضوعية: *NONAGENARIANS, *OLDER patients, *AGE groups, *KIDNEY transplantation, *AORTIC valve insufficiency, *HEART valve prosthesis implantation, *ACUTE kidney failure, *AORTIC stenosis
مصطلحات جغرافية: FRANCE
مستخلص: Background: Given that life expectancy has improved, nonagenarians have become a significant proportion of world population. As aortic stenosis is primarily a disease of the elderly, the need for invasive cardiac approaches is expected to increase in people of extreme age. Herein, we compare the in-hospital adverse clinical outcomes and mortality after transcatheter aortic valve implantation (TAVI) procedures in nonagenarians to younger than 90 year old patients.Methods: A retrospective study was conducted on 1336 patients who underwent TAVI between January 2016 and March 2020 at Toulouse University Hospital, Rangueil, France. Post-TAVI adverse clinical outcomes were defined according to Valve Academic Research Consortium-2 Criteria. The studied population was divided into 2 groups according to age.Results: Out of 1336 patients, 250 (18.7%) were nonagenarians with a mean age of 91.8 ± 1.9 years. Pacemaker implantation (12.4% vs 12.1%), stroke (2% vs 1.8%), and major vascular complications (9.2% vs 6.7%) were more common in nonagenarians, whereas acute kidney injury (1.2% vs 2.7%) and major bleeding events (3.2% vs 3.4%) were more common in the <90-year-old group. Nonagenarians are more likely to develop major vascular complications (odds ratio [OR] = 1.76 95% confidence interval [CI] 1.04-3, P = .03). The prevalence of in-hospital mortality in nonagenarians and <90-year-old patients were 5.2% and 2%, respectively. Survival analysis showed a significant difference in mortality during hospitalization period only ( P = .04).Conclusion: The prevalence of TAVI procedural success is remarkably high in nonagenarians and comparable to that of younger patients. However, the in-hospital mortality rate was 2-fold more than that of <90-year-old patients. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
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