دورية أكاديمية
Effect of the use of an endotracheal tube and stylet versus an endotracheal tube alone on first-attempt intubation success: a multicentre, randomised clinical trial in 999 patients.
| العنوان: | Effect of the use of an endotracheal tube and stylet versus an endotracheal tube alone on first-attempt intubation success: a multicentre, randomised clinical trial in 999 patients. |
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| المؤلفون: | Jaber, Samir1,2 (AUTHOR) s-jaber@chu-montpellier.fr, Rollé, Amélie3 (AUTHOR), Godet, Thomas4 (AUTHOR), Terzi, Nicolas5 (AUTHOR), Riu, Béatrice6 (AUTHOR), Asfar, Pierre7 (AUTHOR), Bourenne, Jeremy8 (AUTHOR), Ramin, Séverin9 (AUTHOR), Lemiale, Virginie10 (AUTHOR), Quenot, Jean-Pierre11,12,13 (AUTHOR), Guitton, Christophe14 (AUTHOR), Prudhomme, Eloi15,16 (AUTHOR), Quemeneur, Cyril17 (AUTHOR), Blondonnet, Raiko4 (AUTHOR), Biais, Mathieu18,19 (AUTHOR), Muller, Laurent20 (AUTHOR), Ouattara, Alexandre21,22 (AUTHOR), Ferrandiere, Martine23 (AUTHOR), Saint-Léger, Piehr24 (AUTHOR), Rimmelé, Thomas25 (AUTHOR) |
| المصدر: | Intensive Care Medicine. Jun2021, Vol. 47 Issue 6, p653-664. 12p. 1 Diagram, 2 Charts, 2 Graphs. |
| مصطلحات موضوعية: | *ENDOTRACHEAL tubes, *TRACHEA intubation, *INTUBATION, *INTENSIVE care units, *CLINICAL trials, *RANDOMIZED controlled trials, *RESEARCH, *RESEARCH methodology, *MEDICAL cooperation, *EVALUATION research, *CATASTROPHIC illness, *COMPARATIVE studies |
| مستخلص: | |
| قاعدة البيانات: | Academic Search Index |
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1 |
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asx Academic Search Index 150853809 1307 6 Academic Journal academicJournal 1307.29418945313 |
| PLink |
https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=asx&AN=150853809&custid=s6537998&authtype=sso |
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Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22Jaber%2C+Samir%22">Jaber, Samir</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> s-jaber@chu-montpellier.fr</i><br /><searchLink fieldCode="AR" term="%22Rollé%2C+Amélie%22">Rollé, Amélie</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Godet%2C+Thomas%22">Godet, Thomas</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Terzi%2C+Nicolas%22">Terzi, Nicolas</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Riu%2C+Béatrice%22">Riu, Béatrice</searchLink><relatesTo>6</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Asfar%2C+Pierre%22">Asfar, Pierre</searchLink><relatesTo>7</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bourenne%2C+Jeremy%22">Bourenne, Jeremy</searchLink><relatesTo>8</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ramin%2C+Séverin%22">Ramin, Séverin</searchLink><relatesTo>9</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lemiale%2C+Virginie%22">Lemiale, Virginie</searchLink><relatesTo>10</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Quenot%2C+Jean-Pierre%22">Quenot, Jean-Pierre</searchLink><relatesTo>11,12,13</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Guitton%2C+Christophe%22">Guitton, Christophe</searchLink><relatesTo>14</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Prudhomme%2C+Eloi%22">Prudhomme, Eloi</searchLink><relatesTo>15,16</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Quemeneur%2C+Cyril%22">Quemeneur, Cyril</searchLink><relatesTo>17</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Blondonnet%2C+Raiko%22">Blondonnet, Raiko</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Biais%2C+Mathieu%22">Biais, Mathieu</searchLink><relatesTo>18,19</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Muller%2C+Laurent%22">Muller, Laurent</searchLink><relatesTo>20</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ouattara%2C+Alexandre%22">Ouattara, Alexandre</searchLink><relatesTo>21,22</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ferrandiere%2C+Martine%22">Ferrandiere, Martine</searchLink><relatesTo>23</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Saint-Léger%2C+Piehr%22">Saint-Léger, Piehr</searchLink><relatesTo>24</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rimmelé%2C+Thomas%22">Rimmelé, Thomas</searchLink><relatesTo>25</relatesTo> (AUTHOR) ) Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => <searchLink fieldCode="JN" term="%22Intensive+Care+Medicine%22">Intensive Care Medicine</searchLink>. Jun2021, Vol. 47 Issue 6, p653-664. 12p. 1 Diagram, 2 Charts, 2 Graphs. ) Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => *<searchLink fieldCode="DE" term="%22ENDOTRACHEAL+tubes%22">ENDOTRACHEAL tubes</searchLink><br />*<searchLink fieldCode="DE" term="%22TRACHEA+intubation%22">TRACHEA intubation</searchLink><br />*<searchLink fieldCode="DE" term="%22INTUBATION%22">INTUBATION</searchLink><br />*<searchLink fieldCode="DE" term="%22INTENSIVE+care+units%22">INTENSIVE care units</searchLink><br />*<searchLink fieldCode="DE" term="%22CLINICAL+trials%22">CLINICAL trials</searchLink><br />*<searchLink fieldCode="DE" term="%22RANDOMIZED+controlled+trials%22">RANDOMIZED controlled trials</searchLink><br />*<searchLink fieldCode="DE" term="%22RESEARCH%22">RESEARCH</searchLink><br />*<searchLink fieldCode="DE" term="%22RESEARCH+methodology%22">RESEARCH methodology</searchLink><br />*<searchLink fieldCode="DE" term="%22MEDICAL+cooperation%22">MEDICAL cooperation</searchLink><br />*<searchLink fieldCode="DE" term="%22EVALUATION+research%22">EVALUATION research</searchLink><br />*<searchLink fieldCode="DE" term="%22CATASTROPHIC+illness%22">CATASTROPHIC illness</searchLink><br />*<searchLink fieldCode="DE" term="%22COMPARATIVE+studies%22">COMPARATIVE studies</searchLink> ) Array ( [Name] => Abstract [Label] => Abstract [Group] => Ab [Data] => <bold>Purpose: </bold>The effect of the routine use of a stylet during tracheal intubation on first-attempt intubation success is unclear. We hypothesised that the first-attempt intubation success rate would be higher with tracheal tube + stylet than with tracheal tube alone.<bold>Methods: </bold>In this multicentre randomised controlled trial, conducted in 32 intensive care units, we randomly assigned patients to tracheal tube + stylet or tracheal tube alone (i.e. without stylet). The primary outcome was the proportion of patients with first-attempt intubation success. The secondary outcome was the proportion of patients with complications related to tracheal intubation. Serious adverse events, i.e., traumatic injuries related to tracheal intubation, were evaluated.<bold>Results: </bold>A total of 999 patients were included in the modified intention-to-treat analysis: 501 (50%) to tracheal tube + stylet and 498 (50%) to tracheal tube alone. First-attempt intubation success occurred in 392 patients (78.2%) in the tracheal tube + stylet group and in 356 (71.5%) in the tracheal tube alone group (absolute risk difference, 6.7; 95%CI 1.4-12.1; relative risk, 1.10; 95%CI 1.02-1.18; P = 0.01). A total of 194 patients (38.7%) in the tracheal tube + stylet group had complications related to tracheal intubation, as compared with 200 patients (40.2%) in the tracheal tube alone group (absolute risk difference, - 1.5; 95%CI - 7.5 to 4.6; relative risk, 0.96; 95%CI 0.83-1.12; P = 0.64). The incidence of serious adverse events was 4.0% and 3.6%, respectively (absolute risk difference, 0.4; 95%CI, - 2.0 to 2.8; relative risk, 1.10; 95%CI 0.59-2.06. P = 0.76).<bold>Conclusions: </bold>Among critically ill adults undergoing tracheal intubation, using a stylet improves first-attempt intubation success. [ABSTRACT FROM AUTHOR] ) |
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