دورية أكاديمية
أعرض في EDS

Early predictors of diabetic retinopathy in type 1 diabetes: The Retinopathy Champagne Ardenne Diabète (ReCAD) study.

التفاصيل البيبلوغرافية
العنوان: Early predictors of diabetic retinopathy in type 1 diabetes: The Retinopathy Champagne Ardenne Diabète (ReCAD) study.
المؤلفون: Diallo, Alpha Mamadou1 amdiallo@chu-reims.fr, Novella, Jean-Luc2, Lukas, Céline1, Souchon, Pierre-François3, Dramé, Moustapha2, François, Maud1, Decoudier, Bénédicte1, Barraud, Sara1, Salmon, Anne-Sophie3, Ancelle, Déborah1, Arndt, Carl4, Delemer, Brigitte1
المصدر: Journal of Diabetes & its Complications. Aug2018, Vol. 32 Issue 8, p753-758. 6p.
مستخلص: Aims: To determine the relationship between early markers of diabetes control and diabetic retinopathy (DR) in type 1 diabetes.Methods: A historic cohort study was conducted on 712 patients from the CARéDIAB database. HbA1c and usual metabolic parameters were measured one year after diagnosis of diabetes. First occurrences of severe hypoglycemia and ketoacidosis during follow-up were selected as time-dependent markers of diabetes control. Data were analyzed in a Cox model using SPSS software to predict DR with significance level at p-value <0.05.Results: In multivariate regression, any diabetic retinopathy was predicted by HbA1c (HR = 1.38; CI = 1.25-1.52; p < 0.0001), severe hypoglycemia (HR = 3; CI = 1.99-4.52; p < 0.0001), ketoacidosis (HR = 1.96; CI = 1.17-3.22; p = 0.009), and age at diagnosis (HR = 1.016; CI = 1.002-1.031; p = 0.02). Proliferative DR was predicted by HbA1c (HR = 1.67; CI = 1.51-1.79; p < 0.0001), severe hypoglycemia (HR = 3.67; CI = 2.74-5.25; p < 0.0001), and ketoacidosis (HR = 2.37; CI = 1.56-3.18; p < 0.0001).Conclusion: This study shows that the failure to achieve diabetes control after the first year of diagnosis as well as early episodes of acute diabetes complications may contribute to the occurrence of diabetic retinopathy in type 1 diabetes patients. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
ResultId 1
Header asx
Academic Search Index
130765250
1269
6
Academic Journal
academicJournal
1269.0439453125
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=asx&AN=130765250&custid=s6537998&authtype=sso
FullText Array ( [Availability] => 0 )
Items Array ( [Name] => Title [Label] => Title [Group] => Ti [Data] => Early predictors of diabetic retinopathy in type 1 diabetes: The Retinopathy Champagne Ardenne Diab&#232;te (ReCAD) study. )
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Diallo%2C+Alpha+Mamadou%22&quot;&gt;Diallo, Alpha Mamadou&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt; amdiallo@chu-reims.fr&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Novella%2C+Jean-Luc%22&quot;&gt;Novella, Jean-Luc&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lukas%2C+C&#233;line%22&quot;&gt;Lukas, C&#233;line&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Souchon%2C+Pierre-Fran&#231;ois%22&quot;&gt;Souchon, Pierre-Fran&#231;ois&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Dram&#233;%2C+Moustapha%22&quot;&gt;Dram&#233;, Moustapha&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Fran&#231;ois%2C+Maud%22&quot;&gt;Fran&#231;ois, Maud&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Decoudier%2C+B&#233;n&#233;dicte%22&quot;&gt;Decoudier, B&#233;n&#233;dicte&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Barraud%2C+Sara%22&quot;&gt;Barraud, Sara&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Salmon%2C+Anne-Sophie%22&quot;&gt;Salmon, Anne-Sophie&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ancelle%2C+D&#233;borah%22&quot;&gt;Ancelle, D&#233;borah&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Arndt%2C+Carl%22&quot;&gt;Arndt, Carl&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Delemer%2C+Brigitte%22&quot;&gt;Delemer, Brigitte&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt; )
Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Journal+of+Diabetes+%26+its+Complications%22&quot;&gt;Journal of Diabetes &amp; its Complications&lt;/searchLink&gt;. Aug2018, Vol. 32 Issue 8, p753-758. 6p. )
Array ( [Name] => Abstract [Label] => Abstract [Group] => Ab [Data] => &lt;bold&gt;Aims: &lt;/bold&gt;To determine the relationship between early markers of diabetes control and diabetic retinopathy (DR) in type 1 diabetes.&lt;bold&gt;Methods: &lt;/bold&gt;A historic cohort study was conducted on 712 patients from the CAR&#233;DIAB database. HbA1c and usual metabolic parameters were measured one year after diagnosis of diabetes. First occurrences of severe hypoglycemia and ketoacidosis during follow-up were selected as time-dependent markers of diabetes control. Data were analyzed in a Cox model using SPSS software to predict DR with significance level at p-value &lt;0.05.&lt;bold&gt;Results: &lt;/bold&gt;In multivariate regression, any diabetic retinopathy was predicted by HbA1c (HR = 1.38; CI = 1.25-1.52; p &lt; 0.0001), severe hypoglycemia (HR = 3; CI = 1.99-4.52; p &lt; 0.0001), ketoacidosis (HR = 1.96; CI = 1.17-3.22; p = 0.009), and age at diagnosis (HR = 1.016; CI = 1.002-1.031; p = 0.02). Proliferative DR was predicted by HbA1c (HR = 1.67; CI = 1.51-1.79; p &lt; 0.0001), severe hypoglycemia (HR = 3.67; CI = 2.74-5.25; p &lt; 0.0001), and ketoacidosis (HR = 2.37; CI = 1.56-3.18; p &lt; 0.0001).&lt;bold&gt;Conclusion: &lt;/bold&gt;This study shows that the failure to achieve diabetes control after the first year of diagnosis as well as early episodes of acute diabetes complications may contribute to the occurrence of diabetic retinopathy in type 1 diabetes patients. [ABSTRACT FROM AUTHOR] )
RecordInfo Array ( [BibEntity] => Array ( [Identifiers] => Array ( [0] => Array ( [Type] => doi [Value] => 10.1016/j.jdiacomp.2018.05.011 ) ) [Languages] => Array ( [0] => Array ( [Code] => eng [Text] => English ) ) [PhysicalDescription] => Array ( [Pagination] => Array ( [PageCount] => 6 [StartPage] => 753 ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Early predictors of diabetic retinopathy in type 1 diabetes: The Retinopathy Champagne Ardenne Diabète (ReCAD) study. [Type] => main ) ) ) [BibRelationships] => Array ( [HasContributorRelationships] => Array ( [0] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Diallo, Alpha Mamadou ) ) ) [1] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Novella, Jean-Luc ) ) ) [2] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Lukas, Céline ) ) ) [3] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Souchon, Pierre-François ) ) ) [4] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Dramé, Moustapha ) ) ) [5] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => François, Maud ) ) ) [6] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Decoudier, Bénédicte ) ) ) [7] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Barraud, Sara ) ) ) [8] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Salmon, Anne-Sophie ) ) ) [9] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Ancelle, Déborah ) ) ) [10] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Arndt, Carl ) ) ) [11] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Delemer, Brigitte ) ) ) ) [IsPartOfRelationships] => Array ( [0] => Array ( [BibEntity] => Array ( [Dates] => Array ( [0] => Array ( [D] => 01 [M] => 08 [Text] => Aug2018 [Type] => published [Y] => 2018 ) ) [Identifiers] => Array ( [0] => Array ( [Type] => issn-print [Value] => 10568727 ) ) [Numbering] => Array ( [0] => Array ( [Type] => volume [Value] => 32 ) [1] => Array ( [Type] => issue [Value] => 8 ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Journal of Diabetes & its Complications [Type] => main ) ) ) ) ) ) )
IllustrationInfo