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1دورية أكاديمية
مصطلحات موضوعية: Cullin, E3 ubiquitin ligases, F-box protein), HECTs (Homologous to the E6AP carboxyl terminus), RING-in between-RING (RBR), SCF (Skp1, cancer, neurological disorders, really interesting new gene (RING), ubiquitin chain assembly
وصف الملف: Electronic-eCollection; application/pdf
الإتاحة: https://doi.org/10.17863/CAM.65865Test
https://www.repository.cam.ac.uk/handle/1810/318747Test -
2رسالة جامعية
المؤلفون: Shimizu, Satoshi, 清水, 覚司, シミズ, サトシ
المساهمون: 中川, 一路, 岩田, 想, 松本, 智裕
مصطلحات موضوعية: linear ubiquitin, linear ubiquitin chain assembly complex (LUBAC), programmed cell death, NF-kappaB
وصف الملف: application/pdf
Degree: 博士(医学) -- Doctor of Medical Science -- 京都大学
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3دورية أكاديمية
المؤلفون: Ivona Aksentijevich, Qing Zhou
المصدر: Frontiers in Immunology, Vol 8 (2017)
مصطلحات موضوعية: TNFAIP3/A20, linear ubiquitin chain assembly complex, OTULIN, haploinsufficiency of A20, LUBAC deficiency, otulipenia/otulin-related autoinflammatory syndrome, Immunologic diseases. Allergy, RC581-607
وصف الملف: electronic resource
العلاقة: http://journal.frontiersin.org/article/10.3389/fimmu.2017.00399/fullTest; https://doaj.org/toc/1664-3224Test
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المساهمون: Laman, Heike [0000-0002-6089-171X], Apollo - University of Cambridge Repository
المصدر: Licchesi, J D F, Laman, H, Ikeda, F & Bolanos-Garcia, V M 2020, ' Editorial : E3 Ubiquitin Ligases: From Structure to Physiology ', Frontiers in Physiology, vol. 11, 621053 . https://doi.org/10.3389/fphys.2020.621053Test
Frontiers in Physiology, Vol 11 (2020)مصطلحات موضوعية: F-box protein), HECTs (Homologous to the E6AP carboxyl terminus), lcsh:QP1-981, really interesting new gene (RING), biology, Physiology, neurological disorders, Cancer, E3 ubiquitin ligases, medicine.disease, F-box protein, lcsh:Physiology, Cullin, Cell biology, RING-in between-RING (RBR), SCF (Skp1, Ubiquitin, Physiology (medical), medicine, biology.protein, cancer, ubiquitin chain assembly
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8678e123eff83509c8dcd74de6f2dfTest
https://purehost.bath.ac.uk/ws/files/215099001/Licchesi_et_al_2020.pdfTest -
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المؤلفون: Vik Ven Eng, Madeleine A. Wemyss, Jaclyn S. Pearson
المصدر: Seminars in Cell & Developmental Biology
مصطلحات موضوعية: NSA, necrosulfonamide, T4SS, type IV secretion system, RHIM, RIP homotypic interaction motif, ERK, extracellular signal-regulated kinases, MDP, muramyl dipeptide, TNF, tumour necrosis factor, RIP kinase, 0302 clinical medicine, UPR, unfolded protein response, RIG-I, cytosolic retinoic acid-inducible gene I, T3SS, type III secretion system, TGFβ, transforming growth factor beta, AEC, airway epithelial cell, MCMV, murine cytomegalovirus, NP, nucleoprotein, ZBP1, Z-DNA binding protein, Kgp, lysine-specific protease gingipain, COTV, Cotia poxvirus, COVID-19, coronavirus disease 2019, XIAP, X-linked inhibitor of apoptosis protein, ALRs, AIM2-like receptors, KD, kinase domain, Kinase, Th1, T helper 1, BMDMs, bone marrow-derived macrophages, HFMD, hand foot and mouth disease, BclxL, Bcl-extra large, TRAM, translocating chain-associated membrane protein, dsRNA, double stranded RNA, LMP1, latent membrane protein, Cell biology, Intracellular signal transduction, CARD, caspase activation and recruitment domain, SDH, succinate dehydrogenase, TRPM7, transient receptor potential cation channel subfamily M member 7, IKK, IĸB kinase, MAVS, mitochondrial antiviral signaling proteins, NK, natural killer, TRIF, TIR-domain-containing adapter-inducing interferon-β, ISGF3, IFN-stimulated gene factor 3, Cell signaling, AIM2, absent in melanoma 2, PD, Parkinson disease, Yop, Yersinia outer protein, JEV, Japanese encephalitis virus, Poly(I:C), polyinosinic:polycytidylic acid, Article, PKR, protein kinase R, vIRA, viral inhibitor of RIP activation, RIPK2, 03 medical and health sciences, RIPK1, BAV, BeAn 58058 poxvirus, NLRs, nucleotide-binding domain–like receptors, ORF, open reading frame, IAV, influenza A virus, MyD88, myeloid differentiation factor 88, CD, Crohn’s disease, Humans, SARS, severe acute respiratory syndrome, DAMPs, danger-associated molecular patterns, GSDMD, gasdermin D, TLR, toll-like receptor, UL45/UL48, human CMV envelope protein 45/48, RR, ribonucleotide reductase, OMV, outer membrane vesicle, NO, nitric oxide, Pathogen-associated molecular pattern, TRAILR, TNF-related apoptosis-inducing ligand receptor, COR, C-terminal of Roc, DR, death receptor, GEF, guanidine exchange factor, IĸB, inhibitor of ĸB, WT, wild-type, Saporins, HMGB1, high mobility group box 1, IL, interleukin, MDA5, melanoma differentiation-associated protein 5, 030104 developmental biology, siRNA, small interfering RNA, TBK1, TANK-binding kinase 1, PFT, pore-forming toxins, ISGs, interferon stimulated genes, Cif, cycle inhibiting factor, RSV, respiratory syncytial virus, TRADD, TNFR1-associated death domain protein, Bacterial infection, PAMPs, pathogen associated molecular patterns, 030217 neurology & neurosurgery, Developmental Biology, 0301 basic medicine, NSP, non-structural protein, Bcl-2, B-cell lymphoma 2, CA6, coxsackievirus A6, DENV, dengue virus, E3L, vaccinia virus protein E3 long, TAK1, TGFβ-activated kinase 1, iE-DAP, Ɣ-d-glutamyl-mesodiaminopimelic acid, AP-1, activator protein 1, vICA, viral inhibitor of caspase-8 activation, ZIKV, Zika virus, HIV-1, human immunodeficiency virus type 1, PI3K, PI3 kinase, ATG16L1, autophagy-related 16-like 1, CVB, coxsackievirus B3, PRRs, pattern recognition receptors, SNPs (line 657) ssRNA, single-stranded RNA, MAPKs, mitogen-activated protein kinases, Pathogen, HSV, Herpes simplex virus, DAI, DNA-dependent activator of IRFs, EBV, Epstein-Barr virus, M45, murine CMV virion associated protein M45, PGN, bacterial peptidoglycan, DAP, diaminopimelic acid, UBE2N, ubiquitin-conjugating enzyme E2N, ID, intermediate domain, NleB, non-LEE encoded effector protein B, c-FLIP, cellular FLICE inhibitory protein, DRP1, dynamin-related protein 1, vMLKL, viral MLKL-like proteins, IRG1, immunoresponsive gene 1, LRR, leucine-rich repeat, NF-ĸB, nuclear factor-ĸB, TNFR1, TNF receptor type 1, WNV, West Nile virus, HCV, hepatitis C virus, JNK, c-Jun N-terminal kinase, Host-Pathogen Interactions, LPS, lipopolysaccharide, Roc, Ras-of-complex, PVM, pneumonia virus of mice, NET, neutrophil extracellular traps, HAEC, human aortic endothelial cells, ASC, apoptosis-associated speck-like protein, NLRC4, NLR family CARD domain containing 4, SARS-3a, SARS-CoV ORF protein 3a, Cell death, VSV, vesicular stomatitis virus, PnCW, pneumococcal cell wall, RIPKs, receptor interacting protein kinases, Mtb, Mycobacterium tuberculosis, HBeAg, hepatitis B e antigen, Biology, CNS, central nervous system, cIAPs, cellular inhibitor of apoptosis proteins, ER, endoplasmic reticulum, IFI44L, IFN-induced protein 44-like, NOD, nucleotide-binding oligomerization domain, ROS, reactive oxygen species, DISCs, death-inducing signaling complexes, NoV, norovirus, 3Cpro, viral non-structural protein 3C, IFN, interferon, VV, vaccinia virus, PR, protease, TRAF, TNFR associated factors, Inflammation, CNF1, cytotoxic necrotising factor 1, HCMV, human cytomegalovirus, KO, knockout, NLRP3, NLR family pyrin domain containing 3, Nec-1, necrostatin-1, Autophagy, IRFs, IFN regulatory factors, Cell Biology, CMV, cytomegalovirus, MLKL, mixed-lineage kinase-domain like protein, HPV, human papilloma virus, NAIPs, NLR family apoptosis inhibitory proteins, HBV, hepatitis B virus, PI3P, phosphatidylinositol 3-phosphate, RDA, RIPK1-dependent apoptosis, Viral infection, MKKs, MAPK kinases, LUBAC, linear ubiquitin chain assembly complex, BVDV, bovine viral diarrhoea virus
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628bb448c2d6de5b9d7755cdadd35794Test
http://europepmc.org/articles/PMC7448748Test -
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المصدر: Frontiers in Physiology
مصطلحات موضوعية: HECTs (Homologous to the E6AP carboxyl terminus), F-box protein), Editorial, RING-in between-RING (RBR), SCF (Skp1, really interesting new gene (RING), Physiology, neurological disorders, ubiquitin chain assembly, cancer, E3 ubiquitin ligases, Cullin
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eaa3fd084c2a56e2743b4f90ce793164Test
https://radar.brookes.ac.uk/radar/items/713d1b19-1900-4964-8ef0-2dfa5c5960b0/1Test/ -
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المؤلفون: Kazuharu Hanada, Noboru Ohsawa, Mikako Shirouzu, Shisako Shoji
المصدر: Biochemical Journal
مصطلحات موضوعية: 0301 basic medicine, ubiquitin-chain assembly, Architecture domain, Ubiquitin-Protein Ligases, Sequence Homology, medicine.disease_cause, Biochemistry, ubiquitin oligomer, ubiquitin ligases, 03 medical and health sciences, Ubiquitin, Catalytic Domain, medicine, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Molecular Biology, Gene, Research Articles, ubiquitin system, Zinc finger, Mutation, biology, Ubiquitination, RNF52, Cell Biology, Cell biology, Ubiquitin ligase, 030104 developmental biology, Ubiquitin-Conjugating Enzymes, Domain (ring theory), biology.protein, BRAP, Function (biology), Research Article, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a5c8acf20ada305e751f74acdb1334Test
https://doi.org/10.1042/bcj20161104Test -
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مصطلحات موضوعية: Physiology, E3 ubiquitin ligases, really interesting new gene (RING), HECTs (Homologous to the E6AP carboxyl terminus), RING-in between-RING (RBR), SCF (Skp1, Cullin, F-box protein), ubiquitin chain assembly, cancer, neurological disorders
وصف الملف: application/pdf; text/xml
الإتاحة: https://doi.org/10.17863/CAM.62114Test
https://www.repository.cam.ac.uk/handle/1810/315006Test -
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المؤلفون: Andrew R. Clark, Michael Ohlmeyer
المصدر: Pharmacology & Therapeutics
مصطلحات موضوعية: 0301 basic medicine, PRR, pattern recognition receptor, IκBα, α inhibitor of NF-κB, IKK, IκBα kinase, AP-1, activator protein 1, law.invention, Serine, S1PR, S1P receptor, 0302 clinical medicine, DC, dendritic cell, law, Heterotrimeric G protein, Neoplasms, CCR4/NOT, carbon catabolite repressor 4/never on TATA-less, PP2A, protein phosphatase 2A, TGFβ, transforming growth factor β, Pharmacology (medical), TIRAP, Toll/interleukin 1 receptor domain-containing adaptor protein, Protein Phosphatase 2, Threonine, Phosphorylation, Protein phosphatase 2A, Cancer, chemistry.chemical_classification, UVB, ultraviolet B, TNF, tumor necrosis factor, TTP, tristetraprolin, Neurodegeneration, Neurodegenerative Diseases, SphK, sphingosine kinase, PAD, PP2A-activating drug, 3. Good health, Cell biology, TRIF, Toll/interleukin 1 receptor domain-containing adaptor inducing interferon β, 030220 oncology & carcinogenesis, JNK, cJun N-terminal kinase, LCMT-1, leucine carboxymethyl transferase 1, STRN, striatin, medicine.symptom, Alzheimer’s disease, PME-1, protein phosphatase methylesterase 1, PAMP, pathogen-associated molecular pattern, TAB, TAK1 binding protein, Signal Transduction, TLR, Toll-like receptor, BBB, blood-brain barrier, NF-κB, nuclear factor κ enhancer of activated B cells, Inflammation, MKK, MAPK kinase, macromolecular substances, AD, Alzheimer’s disease, CNS, central nervous system, Article, MS, multiple sclerosis, Multiple sclerosis, TAK1, transforming growth factor β-activated kinase, 03 medical and health sciences, ROS, reactive oxygen species, Drug Development, MyD88, myeloid differentiation factor 88, medicine, Animals, Humans, TRAF, TNF receptor interacting factor, MK2, MAPK-activated kinase 2, S1P, sphingosine-1-phosphate, Pharmacology, HEAT, Huntingtin - Elongation factor - A subunit of PP2A - Target of rapamycin domain, NFT, neurofibrillary tangles, Protein phosphatase 2, medicine.disease, IL, interleukin, 030104 developmental biology, Enzyme, chemistry, CIP2A, cancerous inhibitor of PP2A, Suppressor, LUBAC, linear ubiquitin chain assembly complex, TRAM, Toll/interleukin 1 receptor domain-containing adaptor molecule, IRF, interferon-regulatory factor, EAE, experimental autoimmune encephalopathy, MAPK, mitogen-activated protein kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f228fbbe77e7d6b25561c5f3c1735eTest
https://pubmed.ncbi.nlm.nih.gov/31158394Test -
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المؤلفون: Jiazhen, Zhang, Kristopher, Clark, Toby, Lawrence, Mark W, Peggie, Philip, Cohen
المصدر: Biochemical Journal
مصطلحات موضوعية: IL-1, interleukin-1, TNF, tumour necrosis factor, linear ubiquitin chain assembly complex (LUBAC), M-CSF, macrophage colony-stimulating factor, Mice, Serine, TRAF, TNF receptor-associated factor, nuclear factor κB (NF-κB), PP1γ, protein phosphatase 1γ, Gene Knock-In Techniques, Phosphorylation, IKK, IκB kinase, Cells, Cultured, IκB, inhibitor of NF-κB, Intracellular Signaling Peptides and Proteins, interleukin-1 (IL-1), MAP Kinase Kinase Kinases, Recombinant Proteins, BMDM, bone-marrow-derived macrophage, I-kappa B Kinase, JNK, c-Jun N-terminal kinase, LPS, lipopolysaccharide, HA, haemaglutinnin, NF-κB, nuclear factor κB, TLR, Toll-like receptor, Mice, Transgenic, Accelerated Publication, MKK, MAPK kinase, HEK, human embryonic kidney, Animals, Humans, Protein Interaction Domains and Motifs, TAK1, transforming growth factor β-activated kinase-1, Protein Kinase Inhibitors, inhibitor of nuclear factor κB kinase (IKK), E, embryonic day, HOIP, HOIL1 [haem-oxidized IRP2 (iron regulatory protein 2) ubiquitin ligase 1]-interacting protein, TAB, TAK1-binding protein, NEMO, NF-κB essential modulator, Ubiquitination, Embryo, Mammalian, MEF, mouse embryonic fibroblast, Enzyme Activation, HEK293 Cells, Amino Acid Substitution, transforming growth factor β-activated kinase-1 (TAK1), LUBAC, linear ubiquitin chain assembly complex, Mutant Proteins, Protein Processing, Post-Translational, MAPK, mitogen-activated protein kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::731e212e08870fbaa257520d76ff4c7dTest
http://europepmc.org/articles/PMC4206954Test