Trifecta St. Jude medical® aortic valve in pulmonary position
| العنوان: | Trifecta St. Jude medical® aortic valve in pulmonary position |
|---|---|
| المؤلفون: | Branco Mimic, Antonio F. Corno, Alan G. Dawson, Gregory J Skinner, Suhair O. Shebani, Aidan P Bolger, Simone Speggiorin |
| المصدر: | Nano Reviews & Experiments Nano Reviews & Experiments, Vol 8, Iss 1 (2017) |
| بيانات النشر: | Informa UK Limited, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Aortic valve, medicine.medical_specialty, pulmonary valve regurgitation, Regurgitation (circulation), right ventricle, 030204 cardiovascular system & hematology, lcsh:Chemical technology, Article, pulmonary valve, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Ventricular outflow tract, lcsh:TP1-1185, 030212 general & internal medicine, Tetralogy of Fallot, Ejection fraction, business.industry, surgical remodelling, Mean age, medicine.disease, Surgery, Cardiac surgery, medicine.anatomical_structure, Congenital heart defects, Pulmonary valve, Cardiology, business, cardiac surgery |
| الوصف: | Introduction: To evaluate an aortic pericardial valve for pulmonary valve (PV) regurgitation after repair of congenital heart defects. Methods: From July 2012 to June 2016 71 patients, mean age 24 ± 13 years (four to years) underwent PV implantation of aortic pericardial valve, mean interval after previous repair = 21 ± 10 years (two to 47 years). Previous surgery at mean age 3.2 ± 7.2 years (one day to 49 years): tetralogy of Fallot repair in 83% (59/71), pulmonary valvotomy in 11% (8/71), relief of right ventricular outflow tract (RVOT) obstruction in 6% (4/71). Pre-operative echocardiography and MRI showed severe PV regurgitation in 97% (69/71), moderate in 3% (2/71) with associated RVOT obstruction. MRI and knowledge-based reconstruction 3D volumetry (KBR-3D-volumetry) showed mean PV regurgitation = 42 ± 9% (20–58%), mean indexed RV end-diastolic volume = 169 ± 33 (130–265) ml m–2 BSA and mean ejection fraction (EF) = 46 ± 8% (33–61%). Cardio-pulmonary exercise showed mean peak O2/uptake = 24 ± 8 ml kg–1 min–1 (14–45 ml kg–1 min–1), predicted max O2/uptake 66 ± 17% (26–97%). Pre-operative NYHA class was I in 17% (12/71) patients, II in 70% (50/71) and III in 13% (9/71). Results: Mean cardio-pulmonary bypass duration was 95 ± 30ʹ (38–190ʹ), mean aortic cross-clamp in 23% (16/71) 46 ± 31ʹ (8–95ʹ), with 77% (55/71) implantations without aortic cross-clamp. Size of implanted PV: 21 mm in seven patients, 23 mm in 33, 25 mm in 23, and 27 mm in eight. The z-score of the implanted PV was −0.16 ± 0.80 (−1.6 to 2.5), effective orifice area indexed (for BSA) of native PV was 1.5 ± 0.2 (1.2 to –2.1) vs. implanted PV 1.2 ± 0.3 (0.76 to –2.5) (p = ns). In 76% (54/71) patients surgical RV modelling was associated. Mean duration of mechanical ventilation was 6 ± 5 h (0–26 h), mean ICU stay 21 ± 11 h (12–64 h), mean hospital stay 6 ± 3 days (three to 19 days). In mean follow-up = 25 ± 14 months (six to 53 months) there were no early/late deaths, no need for cardiac intervention/re-operation, no valve-related complications, thrombosis or endocarditis. Last echocardiography showed absent PV regurgitation in 87.3% (62/71) patients, trivial/mild degree in 11.3% (8/71), moderate degree in 1.45% (1/71), mean max peak velocity through RVOT 1.6 ± 0.4 (1.0–2.4) m s–1. Mean indexed RV end-diastolic volume at MRI/KBR-3D-volumetry was 96 ± 20 (63–151) ml m–2 BSA, lower than pre-operatively (p |
| تدمد: | 2002-2727 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45aeb6a77ff446167e41a381fb450df2Test https://doi.org/10.1080/20022727.2017.1299900Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....45aeb6a77ff446167e41a381fb450df2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20022727 |
|---|