المؤلفون: Guolong Liao, Hanqi Lei, Xiangwei Yang, Xing Fu, Fu Shi, Donggen Jiang, Haiyun Xiong, Yafei Yang, Yu-Peng Feng, Jun Pang, Bing-Biao Lin

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4941-4953 (2021)

مصطلحات موضوعية: Microarray, DFS, disease-free survival, MDSCs, myeloid-derived suppressor cells, AUC, Area under the dose-response curve, Biochemistry, k-NN, K-nearest neighbor, GEP, gene expression profile, Androgen deprivation therapy, Transcriptome, CTLA-4, cytotoxic T-lymphocyte associated protein-4, chemistry.chemical_compound, Prostate cancer, DEmiRs, differentially expressed miRNAs, SCNAs, somatic copy number alterations, Structural Biology, TGFβ, transforming growth factor β, BCR, biochemical recurrence, ICB, immune checkpoint blockade, GEO, Gene Expression Omnibus, NTP, Nearest template prediction, TMB, tumor mutation burden, PD-1, programmed cell death protein-1, NEPC, neuroendocrine prostate cancer, Computer Science Applications, NMF, non-negative matrix factorization, CCLs, cancer cell lines, Tregs, regulatory T cells, miRNAs, EMT, epithelial-mesenchymal transition, mCRPC, metastatic castration-resistant prostate cancer, Biotechnology, Research Article, FDR, false discovery rate, SubMap, Subclass mapping, Molecular subtypes, Biophysics, PCa, prostate cancer, Biology, KEGG, Kyoto Encyclopedia of Genes and Genomes, Olaparib, OS, overall survival, GSEA, Gene Set Enrichment Analysis, microRNA, GO, Gene Ontology, ssGSEA, single-sample gene set enrichment analysis, Genetics, medicine, TNAs, tumor neoantigens, PTEN, miRNAs, microRNAs, IFN, interferon, ADT, androgen deprivation therapy, ComputingMethodologies_COMPUTERGRAPHICS, Taxane, medicine.disease, PD-L1, programmed death-ligand 1, chemistry, Cancer research, biology.protein, TCGA, The Cancer Genome Atlas, MIRcor, miRNA-correlated, AR, androgen receptor, Heterogeneity, TP248.13-248.65, CAFs, cancer-associated fibroblasts

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f138460d0ba30547d9145ec00105384eTest
http://europepmc.org/articles/PMC8433071Test

المؤلفون: Qiong Chen, Bingrong Zhao, Lu Bai, Juan Jiang, Wang Ya, Yuanyuan Li, Chengping Hu, Changjing Cai, Rongjun Wan

المصدر: Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6386-6399 (2021)
Computational and Structural Biotechnology Journal

مصطلحات موضوعية: TIME, tumor immune microenvironment, Lung adenocarcinoma, RT-qPCR, Real-time Quantitative Polymerase Chain Reaction, medicine.medical_treatment, CCLE, Cancer Cell Line Encyclopedia, Biochemistry, GSVA, gene set variation analysis, PBMC, Peripheral Blood Mononuclear Cell, AUC, area under the curve, Structural Biology, TPM, transcripts per kilobase million, GEO, Gene Expression Omnibus, Small nucleolar RNAs, Small nucleolar RNA, Stage (cooking), RSF, random survival forest, ICIs, immune checkpoints inhibitors, NK cell, natural killer cell, snoRNAs, small nucleolar RNAs, LUAD, lung adenocarcinoma, Computer Science Applications, Real-time polymerase chain reaction, medicine.anatomical_structure, Adenocarcinoma, Research Article, Biotechnology, Biophysics, Peripheral blood mononuclear cell, Tumor cell immune infiltration, HIC, immunohistochemistry, Immune system, TIISR signature, ssGSEA, single-sample gene set enrichment analysis, Genetics, medicine, IF, immunofluorescence, ComputingMethodologies_COMPUTERGRAPHICS, GO, gene ontology, Lung, business.industry, TIISR, tumor-infiltrating immune-related snoRNA, Immunotherapy, medicine.disease, HR, hazard ratio, ROC, receiver operating characteristic, Cancer research, Immune checkpoints, TCGA, The Cancer Genome Atlas, FPKM, fragments per kilobase of transcript per million, business, TSI, tissue specificity index, TP248.13-248.65, ncRNA, noncoding RNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2d4043c8554ee6af7977744fd1f51bTest
http://www.sciencedirect.com/science/article/pii/S2001037021004979Test

المؤلفون: Lauri Diehl, Becket Feierbach, Ricardo Ramirez, Neeru Bhardwaj, Jeffrey J. Wallin, Nicholas van Buuren, Scott Turner, Samuel Kim, Dmytro Kornyeyev, H.L. Chan, Abhishek Aggarwal, Patrick Marcellin, Maria Buti, Simon P. Fletcher, Vithika Suri, Hongmei Mo, Anuj Gaggar, Christina Moon, Li Li, Nam Bui, Diana Chen

المصدر: JHEP Reports

مصطلحات موضوعية: animal diseases, Chronic HBV, multiplex immunofluorescence, Inflammation, chemical and pharmacologic phenomena, BCR, B-cell receptor, Immunofluorescence, CHB, chronic HBV infection, Immune system, Interferon, Immune Microenvironment, ALT, alanine aminotransferase, TLS, tertiary lymphoid structures, DEG, differentially expressed gene, Internal Medicine, medicine, Immunology and Allergy, CXCL10, Cytotoxic T cell, TDF, tenofovir disoproxil fumarate, Hepatology, medicine.diagnostic_test, business.industry, Intrahepatic transcriptome, Gastroenterology, mIF, multiplex immunofluorescence, ssGSEA, single sample gene set enrichment analysis, Hepatitis B, biochemical phenomena, metabolism, and nutrition, medicine.disease, FFPE, formalin-fixed paraffin-embedded, PEG-IFNα, pegylated-interferon-α, HBeAg, TCR, T-cell receptor, Immunology, bacteria, medicine.symptom, business, IHC, immunohistochemistry, medicine.drug, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9295587f3a7b2e1a40d65955914d5a2Test
http://europepmc.org/articles/PMC8671126Test

المؤلفون: Qiushi Feng, Zuobing Chen, Xiaosheng Wang, Tianfang Zhang

المصدر: International Immunopharmacology

مصطلحات موضوعية: 0301 basic medicine, Male, Treg, Regulatory T cells, animal diseases, Tfh, T follicular helper cells, MVS, Mechanical ventilatory support, 0302 clinical medicine, NK, Natural killer, Clinical outcomes, Clustering analysis, Immunology and Allergy, Medicine, Cluster Analysis, SOFA, Sequential Organ Failure Assessment, Aged, 80 and over, Ifn response, Middle Aged, Acquired immune system, Th2 cells, Type 2 T helper cells, HLA, Human leukocyte antigen, ICU, Intensive care unit, RF, Random forest, 030220 oncology & carcinogenesis, CV, cross validation, Identification (biology), WGCNA, Weighted gene co-expression network analysis, Female, APACHE II, Acute Physiology and Chronic Health Evaluation, Adult, 2019-20 coronavirus outbreak, Prognostic factor, Coronavirus disease 2019 (COVID-19), Immunology, COVID-19 subtypes, chemical and pharmacologic phenomena, Article, 03 medical and health sciences, pDCs, Plasmacytoid dendritic cells, Immune system, Humans, Aged, Pharmacology, Antiviral immune response, Innate immune system, business.industry, SARS-CoV-2, COVID-19, HFD, Hospital-free days at day 45, biochemical phenomena, metabolism, and nutrition, Th1 cells, Type 1 T helper cells, 030104 developmental biology, Gene expression profiles, bacteria, FDR, False discovery rate, business, ssGSEA, single-sample gene-set enrichment analysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29c9c53129bdd3806308151018449d8Test
https://pubmed.ncbi.nlm.nih.gov/33836368Test

المؤلفون: Hui Lu, Qian Liu, Rongfang Nie, Mengyuan Li, Lin Li, Xiaosheng Wang, Haiying Zhou

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4472-4485 (2021)

مصطلحات موضوعية: Immune subtypes, TIME, tumor immune microenvironment, FDR, false discovery rate, HRD, homologous recombination deficiency, Tumor immune microenvironment, medicine.medical_treatment, Biophysics, Biology, Biochemistry, Transcriptome, OS, overall survival, Immune system, SCNAs, somatic copy number alterations, Structural Biology, ErbB, MDSC, myeloid-derived suppressor cell, Clustering analysis, WGCNA, weighted gene co-expression network analysis, Genetics, medicine, Melanoma, ComputingMethodologies_COMPUTERGRAPHICS, TMB, tumor mutation burden, GO, gene ontology, DSS, disease-specific survival, ICIs, immune checkpoint inhibitors, Cell adhesion molecule, HLA, human leukocyte antigen, TME, tumor microenvironment, Immunotherapy, Cell cycle, medicine.disease, Computer Science Applications, GSEA, gene-set enrichment analysis, Cutaneous melanoma, Cancer research, TCGA, The Cancer Genome Atlas, DMFS, distant-metastasis free survival, EMT, epithelial-mesenchymal transition, ssGSEA, single-sample gene-set enrichment analysis, NK, natural killer, TP248.13-248.65, Biotechnology, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7240d575451a9e79dfd3e9b2cc10531dTest
https://pubmed.ncbi.nlm.nih.gov/34471493Test

المؤلفون: Jinquan Cai, Ruijia Wang, Lin Lin, Hengyuan Pang, Magafurov Dinislam, Ziwei Li, Shihong Zhao, Qun Chen, Chuanlu Jiang, Pengfei Wu, Caijun Zha, Chunbin Duan, Xiangqi Meng, Bo Han

المصدر: EBioMedicine

مصطلحات موضوعية: Research paper, DNA Repair, Cellular differentiation, medicine.medical_treatment, ATRX, alpha thalassemia/mental retardation syndrome X-linked, SAA1, serum amyloid A1, Transcriptome, Mice, 0302 clinical medicine, GSEA, gene set enrichment analysis, GME, glioma microenvironment, MEM, Minimum Essential Media, BER, base excision repair, Midkine, TNFSF4, TNF superfamily member 4, NADP, nicotinamide adenine dinucleotide phosphate, General Medicine, DSBR, DNA double-strand break repair, 030220 oncology & carcinogenesis, NHEJ, nonhomologous end joining, Microglia, IHC, immunohistochemistry, γH2AX, phosphorylated on serine 139 on H2A histone family member X, CNV, copy number variation, IL6, interleukin 6, ATM, ataxia telangiectasia-mutated gene, IGV, Integrative Genomics Viewer, MDK, midkine, KEGG, Kyoto Encyclopedia of Genes and Genomes, PI, protease inhibitor, DDR, DNA damage response, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mrc1, mannose receptor C-type 1, NER, nucleotide excision repair, Glioma, Humans, PTEN, IF, immunofluorescence, GCM, glioma-conditioned medium, IDH, isocitrate dehydrogenase (NADP(+)), Tumor microenvironment, SSBR, DNA single-strand break repair, TMZ, temozolomide, Macrophages, medicine.disease, Mice, Inbred C57BL, body regions, 030104 developmental biology, Pen/Strep, penicillin/streptomycin, HR, homologous recombination, DAPI, 4′,6-diamidino-2-phenylindole, p53, 0301 basic medicine, ATR, Ataxia Telangiectasia And Rad3-Related Protein, qRT-PCR, Quantitative real-time reverse transcription-polymerase chain reaction, DAB, Diaminobenzidine, ChIP, Chromatin immunoprecipitation, Tumor Microenvironment, DNA damage repair, FA, Fanconi anemia, MGMT, O6-methylguanine-DNA methyltransferase, biology, LGG, lower grade glioma, TLS, trans-lesion synthesis, TP53, tumor protein P53, HRP, horseradish peroxidase, Cell Differentiation, Fizz1, found in inflammatory zone 1, SNP, single nucleotide polymorphism, TCGA, The Cancer Genome Atlas dataset, Cytokine, TNFA, tumor necrosis factor alpha, Female, Arg1, arginase 1, DNA repair, SWI/SNF, SWItch/Sucrose Non-Fermentable, MMR, mismatch repair, DMEM, Dulbecco's Modified Eagle Medium, AKT, protein kinase B, CCL2, C-C motif chemokine ligand 2, CGGA, The Chinese Glioma Genome Atlas dataset, C5, Complement C5, Cell Line, Glioma microenvironment, VEGFA, vascular endothelial growth factor A, FBS, fetal bovine serum, PBS, phosphate buffered saline, Cell Line, Tumor, medicine, Animals, ELISA, Enzyme-Linked Immunosorbent Assay, DR, direct repair, GO, gene ontology, ssGSEA, single sample gene set enrichment analysis, FC, fold change, PTEN, phosphatase and tensin homolog, EGFR, epidermal growth factor receptor, TBST, Tris-buffered Saline with Tween 20, NFκB, nuclear factor kappa B, biology.protein, Cancer research, GBM, glioblastoma, EM/PM classification, EGFR module / PDGFRA (platelet derived growth factor receptor A) -based molecular classification, Tumor Suppressor Protein p53

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae288d30336e455721de6bf5436f314bTest
https://doi.org/10.1016/j.ebiom.2019.01.067Test

المؤلفون: Mengyuan Li, Xiaosheng Wang, Haoyu Lyu, Zehang Jiang, Zhixian Liu

المصدر: Computational and Structural Biotechnology Journal, Vol 17, Iss, Pp 1020-1030 (2019)
Computational and Structural Biotechnology Journal

مصطلحات موضوعية: OR, Odds Ratio, APC, Antigen-Presenting Cell, medicine.medical_treatment, Cell, medicine.disease_cause, Biochemistry, HNSCC, Head and Neck Squamous Cell Carcinomas, 0302 clinical medicine, Cancer immunotherapy, Structural Biology, Tumor immunity, Cancer genomics, TMB, Tumor Mutation Burden, HRAS mutations, 0303 health sciences, Mutation, pDCs, Plasmacytoid Dendritic Cells, TP53 mutations, Head and neck squamous cell carcinomas, Computer Science Applications, medicine.anatomical_structure, HPV, Human Papilloma Virus, 030220 oncology & carcinogenesis, TILs, Tumor-Infiltrating Lymphocytes, TIM, Tumor Immune Microenvironment, GSEA, Gene-Set Enrichment Analysis, Biotechnology, Research Article, lcsh:Biotechnology, Biophysics, ssGSEA, single-sample Gene-Set Enrichment Analysis, Genomics, DFS, Disease Free Survival, 03 medical and health sciences, NK, Natural Killer, Immune system, stomatognathic system, Immunity, dMMR, Deficient Mismatch-Repair, lcsh:TP248.13-248.65, Genetics, medicine, otorhinolaryngologic diseases, BH, Benjami and Hochberg, HRAS, neoplasms, 030304 developmental biology, FDR, False Discovery Rate, business.industry, Immunotherapy, stomatognathic diseases, HLA, Human Leukocyte Antigen, OS, Overall Survival, MHC, Major Histocompatibility Complex, Cancer research, business, EMT, Epithelial-Mesenchymal Transition

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d264cf643e6d8b56224fdf93de9b23f2Test
http://www.sciencedirect.com/science/article/pii/S2001037019301527Test

المؤلفون: Jasmine A. McQuerry, Jeffrey T. Chang, Feng Chi, Aritro Nath, Jiayi Liu, Sumana Majumdar, Samuel W. Brady, Patrick A. Cosgrove, Philip J. Moos, Michael Kahn, Andrea Bild

المصدر: Translational Oncology, Vol 14, Iss 1, Pp 100946-(2021)
Translational Oncology

مصطلحات موضوعية: 0301 basic medicine, EMT, Epithelial to mesenchymal transition, Cancer Research, medicine.medical_treatment, Estrogen receptor, MYC, ALDH, Aldehyde dehydrogenases, chemistry.chemical_compound, 0302 clinical medicine, HDAC, CNV, Copy number variations, HER2, human epidermal growth factor receptor 2, MET, mesenchymal-to-epithelial transition, TNBC, triple negative breast cancer, CSL, cancer stem cell-like, EGFR, epidermal growth factor receptor, biology, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Metastatic breast cancer, Oncology, 030220 oncology & carcinogenesis, WES, whole exome sequencing, Chemoresistance, Single-cell RNA-Seq, Original article, ssGSEA, Single-sample Gene Set Enrichment Analysis, WGS, whole genome sequencing, lcsh:RC254-282, 03 medical and health sciences, Breast cancer, medicine, CSL, AXL, Axl receptor tyrosine kinase, Chemotherapy, CBP, CREB-binding protein, CDK 4/6, Cyclin-Dependent Kinase 4/6, ER, estrogen receptor, FGFR1, Fibroblast growth factor receptor, business.industry, HDAC, Histone deacetylase, CD44, Cancer, medicine.disease, CSC, cancer stem cell, PR, progesterone receptor, scRNA-Seq, single cell RNA sequencing, 030104 developmental biology, chemistry, Cancer cell, Cancer research, biology.protein, HDACi, Histone deacetylase inhibitor, CDK 8, Cyclin-Dependent Kinase 8, business, Belinostat

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbd8f78466bfb62d354266ee7be68b4Test
http://www.sciencedirect.com/science/article/pii/S1936523320304381Test

المؤلفون: Guangjian Yang, Henghui Zhang, Xinying Shi, Jianming Ying, Ying Yang, Beibei Mao, Jiyu Wei, Li Xin, Jing Zhang, Yan Wang, Lijia Wu, Lei Guo, Haiyan Xu, Yane Song, Junling Li, Lu Yang

المصدر: Translational Oncology, Vol 14, Iss 1, Pp 100942-(2021)
Translational Oncology

مصطلحات موضوعية: 0301 basic medicine, Lung adenocarcinoma, Molecular alteration, Cancer Research, Chemokine, DFS, disease-free survival, DEGs, differentially expressed genes, Stage IA, Tumour immunity, SNV, single nucleotide variation, lcsh:RC254-282, WES, whole-exome sequencing, 03 medical and health sciences, IO, immune oncology, 0302 clinical medicine, Immune system, Antigen, CNI, copy number instability, MATH, mutant-allele tumour heterogeneity, NSCLC, non-small cell lung cancer, Gene expression, Medicine, Stage (cooking), Relapse, Antigen Gene, Gene, Survival analysis, Original Research, biology, business.industry, ssGSEA, single sample gene set enrichment analysis, biochemical phenomena, metabolism, and nutrition, LUAD, lung adenocarcinoma, CTL, cytotoxic T lymphocyte, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, FFPE, formalin-fixed paraffin-embedded, CTA, cancer-testis antigen, TMB, tumour mutation burden, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa00f3aeda9d024ec10543867a78bb6bTest
http://www.sciencedirect.com/science/article/pii/S1936523320304344Test

المؤلفون: Laura Croce, Luca Chiovato, Mario Rotondi, Gianluca Ricci, Francesca Coperchini, Flavia Magri

المصدر: Cytokine & Growth Factor Reviews

مصطلحات موضوعية: 0301 basic medicine, IL-17, interleukin-17, Chemokine, IL-1, interleukin-1, medicine.medical_treatment, Endocrinology, Diabetes and Metabolism, CCL20, C-C Motif Chemokine Ligand 20, CCL3, C-C Motif Chemokine Ligand 3, Disease, RNA-Seq, RNA sequencing, CXCL8, C-X-C Motif Chemokine Ligand 8, Bioinformatics, Chemokine receptor, 0302 clinical medicine, MERS-CoV, middle east respiratory syndrome coronavirus, Pandemic, BALF, bronchoalveolar lavage fluid, Medicine, Immunology and Allergy, IFN-γ, interferon-γ, IL-6, interleukin-6, CXCL8 - cytokine storm, scRNA-seq, single-cell RNA sequencing, CXCL9, C-X-C Motif Chemokine Ligand 9, biology, CXCL10, TNFα, tumor-necrosis-factor- α, CS, cytokine storm, ICU, intensive care unit, ACE-2, angiotensin-converting enzyme-2, Cytokine release syndrome, Cytokine, 030220 oncology & carcinogenesis, Cytokines, Chemokines, Cytokine Release Syndrome, JAK, Janus kinase, PBMC, peripheral blood mononuclear cell, ATP, adenosine triphosphate, Mini Review, Immunology, CXCL10, C-X-C Motif Chemokine Ligand 10, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, IL1β, interleukin-1 β, HIV-1-2, human immunodeficiency virus-1-2, CXCL1, C-X-C Motif Chemokine Ligand 1, Humans, GSCF, granulocyte colony-stimulating factor, CCL2, C-C Motif Chemokine Ligand 2, CCL5, C-C Motif Chemokine Ligand 5, ARDS, acute respiratory distress syndrome, Covid-19, coronavirus disease 2019, CCL19, C-C Motif Chemokine Ligand 19, business.industry, SARS-CoV-2, COVID-19, ssGSEA, single sample gene set enrichment analysis, medicine.disease, Th17, T-Helper-17, CXCR3, CXC-chemokine receptor 3, 030104 developmental biology, biology.protein, SARS-COV-2, severe acute respiratory syndrome coronavirus 2, MIS-C, multisystem inflammatory syndrome in children, business, Cytokine storm, COVID-19-coronavirus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061c59061e91ac05f9a9937f8240dfeaTest
https://pubmed.ncbi.nlm.nih.gov/33573850Test