نتائج البحث - "splicing factor mutation"

1

دورية أكاديمية

A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex

المؤلفون: Chatrikhi, Rakesh, Feeney, Callen F, Pulvino, Mary J, Alachouzos, Georgios, MacRae, Andrew J, Falls, Zackary, Rai, Sumit, Brennessel, William W, Jenkins, Jermaine L, Walter, Matthew J, Graubert, Timothy A, Samudrala, Ram, Jurica, Melissa S, Frontier, Alison J, Kielkopf, Clara L

المصدر: Cell Chemical Biology. 28(8)

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2sk8s5grTest

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2

كتاب

Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia:DNA is not Destiny

المؤلفون: van der Werf, Inge Margaretha

المصدر: van der Werf , I M 2022 , ' Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia : DNA is not Destiny ' , Dr. , Vrije Universiteit Amsterdam .

مصطلحات موضوعية: Alternatieve Splicing, Splicing Modulatie, Splicing Deregulatie, Splicing Regulator Mutatie, SF3B1, FLT3/ITD, Acute Myeloïde Leukemie, Leukemie in Kinderen, Alternative Splicing, Splicing Modulation, Splicing Deregulation, Splicing Factor Mutation, Acute Myeloid Leukemia, Pediatric Acute Myeloid Leukemia

وصف الملف: application/pdf; image/jpeg

العلاقة: https://research.vu.nl/en/publications/d8faf35c-e79a-4702-85e8-47a781d2fc41Test

الإتاحة: https://research.vu.nl/en/publications/d8faf35c-e79a-4702-85e8-47a781d2fc41Test
https://hdl.handle.net/1871.1/d8faf35c-e79a-4702-85e8-47a781d2fc41Test
https://research.vu.nl/ws/files/149261926/I%20M%20%20van%20der%20Werf%20-%20thesis.pdfTest
https://research.vu.nl/ws/files/149261928/I%20M%20%20van%20der%20Werf%20-%20cover.jpgTest
https://research.vu.nl/ws/files/149261930/I%20M%20%20van%20der%20Werf%20-%20toc.pdfTest
https://research.vu.nl/ws/files/149261932/I%20M%20%20van%20der%20Werf%20-%20title_page.pdfTest
https://research.vu.nl/ws/files/149261934/I%20M%20%20van%20der%20Werf%20-%20thesis_redacted.pdfTest

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3

Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia

مصطلحات موضوعية: Acute Myeloid Leukemia, FLT3/ITD, Alternatieve Splicing, SF3B1, Pediatric Acute Myeloid Leukemia, Splicing Factor Mutation, Alternative Splicing, Splicing Deregulatie, Leukemie in Kinderen, Acute Myeloïde Leukemie, Splicing Regulator Mutatie, Splicing Modulation, Splicing Deregulation, Splicing Modulatie

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______4612::3c4d8dde679956b0a91ef6747801fdb5Test
https://research.vu.nl/en/publications/d8faf35c-e79a-4702-85e8-47a781d2fc41Test

4

Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia: DNA is not Destiny

المؤلفون: van der Werf, IM

المساهمون: Kaspers, Gertjan, Cloos, Jacqueline, Wojtuszkiewicz, Anna, Groen, Richard, Hematology laboratory, Kaspers, G.J.L., Cloos, J., Wojtuszkiewicz, Anna Monika, Groen, R.

المصدر: van der Werf, I M 2022, ' Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia : DNA is not Destiny ', Dr., Vrije Universiteit Amsterdam .
van der Werf, IM 2022, ' Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia: DNA is not Destiny ', Doctor of Philosophy, Vrije Universiteit Amsterdam, Netherlands . < https://hdl.handle.net/1871.1/d8faf35c-e79a-4702-85e8-47a781d2fc41Test >

مصطلحات موضوعية: Acute Myeloid Leukemia, FLT3/ITD, Alternatieve Splicing, SF3B1, Pediatric Acute Myeloid Leukemia, Splicing Factor Mutation, Alternative Splicing, Splicing Deregulatie, hemic and lymphatic diseases, Leukemie in Kinderen, Acute Myeloïde Leukemie, Splicing Regulator Mutatie, Splicing Modulation, Splicing Deregulation, neoplasms, Splicing Modulatie

وصف الملف: image/jpeg; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6dd4e80e27187b97e6c318d9fc1758e7Test
https://hdl.handle.net/1871.1/d8faf35c-e79a-4702-85e8-47a781d2fc41Test

5

A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex

المؤلفون: Mary J. Pulvino, Zackary Falls, Matthew J. Walter, Rakesh Chatrikhi, Andrew J. MacRae, Jermaine L. Jenkins, Callen F. Feeney, Clara L. Kielkopf, Melissa S. Jurica, William W. Brennessel, Sumit Rai, Georgios Alachouzos, Alison J. Frontier, Timothy A. Graubert, Ram Samudrala

المصدر: Cell chemical biology, vol 28, iss 8
Cell Chem Biol

مصطلحات موضوعية: Clinical Biochemistry, Mutant, U2AF(65), 01 natural sciences, Biochemistry, Drug Discovery, RNA Precursors, RNA, Neoplasm, Cancer, U2AF2, Molecular Structure, Chemistry, ribonucleoprotein targeting, S34F mutant, spliceosome inhibition, Small molecule, Cell biology, Molecular Docking Simulation, 5.1 Pharmaceuticals, RNA splicing, Molecular Medicine, Female, Development of treatments and therapeutic interventions, Macromolecule, Protein subunit, RNA Splicing, Mutagenesis (molecular biology technique), Biology, splicing factor mutation, Article, U2AF(35), Small Molecule Libraries, U2AF1, Genetics, Humans, therapeutic strategy, Molecular Biology, Pharmacology, 010405 organic chemistry, Mutagenesis, RNA, Splicing Factor U2AF, 0104 chemical sciences, myelodysplastic syndrome, HEK293 Cells, Docking (molecular), Neoplasm, K562 Cells, Function (biology)

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895a2cf142ec23caeae71ba14975f65eTest
https://escholarship.org/uc/item/2sk8s5grTest

6

دورية أكاديمية

Ineffective erythropoiesis in myelodysplastic syndrome / 骨髄異形成症候群における赤血球造血障害

المؤلفون: Atsushi IWAMA, 岩間厚志

المصدر: 臨床血液 / Rinsho Ketsueki. 2018, 59(6):793

7

Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples

المؤلفون: Rebecca C. Poulos, Shiyong Ma, Ranjeeta Menon, Jason W. H. Wong

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Genetics, Whole genome sequencing, Jurkat, In silico, Phosphoproteomics, phosphoproteomics, Biology, Proteogenomics, Proteomics, Jurkat cells, splicing factor mutation, DNA sequencing, 03 medical and health sciences, 030104 developmental biology, Oncology, RNA splicing, RNA-seq, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a977fb5b2604ca58db72f4bf4f1747Test
http://europepmc.org/articles/PMC5707065Test

8

دورية أكاديمية

Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation

المساهمون: J.Y. Fong, L. Pignata, P.-. Goy, K.C. Kawabata, S.C.-. Lee, C.M. Koh, D. Musiani, E. Massignani, A.G. Kotini, A. Penson, C.M. Wun, Y. Shen, M. Schwarz, D.H. Low, A. Rialdi, M. Ki, H. Wollmann, S. Mzoughi, F. Gay, C. Thompson, T. Hart, O. Barbash, G.M. Luciani, M.M. Szewczyk, B.J. Wouter, R. Delwel, E.P. Papapetrou, D. Barsyte-Lovejoy, C.H. Arrowsmith, M.D. Minden, J. Jin, A. Melnick, T. Bonaldi, O. Abdel-Wahab, E. Guccione

مصطلحات موضوعية: AML, Arginine methylation, MDS, MS023, PRMT1, PRMT5, SF3B1, Splicing factor mutation, SRSF2, U2AF1, Settore MED/04 - Patologia Generale, Settore BIO/13 - Biologia Applicata, Settore BIO/11 - Biologia Molecolare

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31408619; info:eu-repo/semantics/altIdentifier/wos/WOS:000480434200009; volume:36; issue:2; firstpage:194; lastpage:209; numberofpages:16; journal:CANCER CELL; https://hdl.handle.net/2434/910134Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85069824657

الإتاحة: https://doi.org/10.1016/j.ccell.2019.07.003Test
https://hdl.handle.net/2434/910134Test

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9

دورية أكاديمية

Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples

المؤلفون: Poulos, Rebecca C., Wong, Jason W.H., Ma, Shiyong, Menon, Ranjeeta

مصطلحات موضوعية: RNA-seq, Jurkat, Splicing factor mutation, Phosphoproteomics, Proteogenomics

العلاقة: Oncotarget; Oncotarget, 2017, v. 8, n. 56, p. 95841-95852; 95852; 56; eid_2-s2.0-85033409208; 95841; http://hdl.handle.net/10722/250887Test

الإتاحة: https://doi.org/10.18632/oncotarget.21339Test
http://hdl.handle.net/10722/250887Test

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النص الكامل

10

مورد إلكتروني

Splicing Deregulation and Splicing Modulation in Acute Myeloid Leukemia: DNA is not Destiny

مصطلحات الفهرس: Alternatieve Splicing, Splicing Modulatie, Splicing Deregulatie, Splicing Regulator Mutatie, SF3B1, FLT3/ITD, Acute Myeloïde Leukemie, Leukemie in Kinderen, Alternative Splicing, Splicing Modulation, Splicing Deregulation, Splicing Factor Mutation, Acute Myeloid Leukemia, Pediatric Acute Myeloid Leukemia, PhD-Thesis - Research and graduation internal

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