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العلاقة: http://purl.org/au-research/grants/nhmrc/627127Test; http://purl.org/au-research/grants/nhmrc/1081182Test; Frontiers in Endocrinology, 2018; 9:741-1-741-11; http://hdl.handle.net/2440/117529Test; Kreuch, D. [0000-0001-5895-8236]; Wu, T. [0000-0003-1656-9210]; Horowitz, M. [0000-0002-0942-0306]; Rayner, C.K. [0000-0002-5527-256X]; Young, R.L. [0000-0001-5116-4951] [0009-0004-8274-9863]

الإتاحة: https://doi.org/10.3389/fendo.2018.00741Test
http://hdl.handle.net/2440/117529Test

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النص الكامل

10

The influence of the gut microbiota on the bioavailability of oral drugs

المؤلفون: Ying Han, Xintong Zhang, Wei Huang, Zhonggao Gao, Mingji Jin

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1789-1812 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: SLC, solute carrier, Bioavailability, AMI, amiodarone, MPA, mycophenolic acid, TLCA, taurolithocholate, ASP, amisulpride, RA, rheumatoid arthritis, Review, NRs, nitroreductases, MDR1, multidrug resistance gene 1, NaGC, sodium glycholate, MATEs, multidrug and toxin extrusion proteins, NMEs, new molecular entities, 0302 clinical medicine, HFD, high fat diet, P-gp, P-glycoprotein, ACS, amphipathic chitosan derivative, Medicine, General Pharmacology, Toxicology and Pharmaceutics, LCA, lithocholic acid, 0303 health sciences, Gastrointestinal tract, IBD, inflammatory bowel disease, pKa, dissociation constant, RBC, red blood cell, FA, folate, OATs, organic anion transporters, 030220 oncology & carcinogenesis, MKC, monoketocholic acid, the GI tract, the gastrointestinal tract, AQP4, aquaporin 4, OCTNs, organic zwitterion/cation, T2D, type 2 diabetes, Gut microbiota, RM1-950, WHO, World Health Organization, 03 medical and health sciences, EcN, Escherichia coli Nissle 1917, Drug Transport Process, BDEPT, the bacteria-directed enzyme prodrug therapy, BCS, biopharmaceutics classification system, NEC, necrotizing enterocolitis, DRPs, digoxin reduction products, NaDC, sodium deoxycholate, Probiotics, CPP, cell-penetrating peptide, OCTs, organic cation transporters, TDCA, taurodeoxycholate, cgr operon, cardiac glycoside reductase operon, RA - Rheumatoid arthritis, DCA, deoxycholic acid, AA, ascorbic acid, BBR, berberine, Personalized medicine, BDDCS, the biopharmaceutics drug disposition classification system, SSZ, sulfasalazine, UDC, ursodeoxycholic acid, PPIs, proton pump inhibitors, BCRP, breast cancer resistance protein, CS, chitosan, Gut flora, Bioinformatics, PD, Parkinson's disease, SLN, solid lipid nanoparticle, SGLT-1, sodium-coupled glucose transporter 1, Oral administration, MRP2, multidrug resistance-associated protein 2, FAO, Food and Agriculture Organization of the United Nations, SVCT-1/2, the sodium-dependent vitamin C transporter-1/2, an OTC drug, an over-the-counter drug, CA, cholic acid, biology, ABC, ATP-binding cassette, T1DM, type 1 diabetes mellitus, NSAIDs, non-steroidal anti-inflammatory drugs, AR, azoreductase, GCDC, glycochenodeoxycholate, Drug delivery, GL, glycyrrhizic acid, PT, pectin, LPS, lipopolysaccharide, TME, the tumor microenvironment, T1D, type 1 diabetes, TCDC, taurochenodeoxycholate, Oral drugs, MDR1a, multidrug resistance protein-1a, SCFAs, short-chain fatty acids, CDCA, chenodeoxycholic acid, 030304 developmental biology, business.industry, dhBBR, dihydroberberine, biology.organism_classification, HTC, hematocrit, PWSDs, poorly water-soluble drugs, Colon-specific drug delivery system, stomatognathic diseases, SP, sulfapyridine, 5-ASA, 5-aminosalicylic acid, BSH, bile salt hydrolase, TCA, taurocholate, Therapeutics. Pharmacology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d001e27a816f9de7d75ff16dd2143ecTest
http://www.sciencedirect.com/science/article/pii/S2211383520307279Test

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