المؤلفون: Silja Hansen Haldrup, Bjørn K. Fabian-Jessing, Thomas Stax Jakobsen, Anna Bøgh Lindholm, Rikke L. Adsersen, Lars Aagaard, Toke Bek, Anne Louise Askou, Thomas J. Corydon

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101242- (2024)

مصطلحات موضوعية: retinal gene therapy, AMD, anti-VEGF, CNV, RNAi therapeutics, miR-agshRNA, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2329050124000585Test; https://doaj.org/toc/2329-0501Test

الوصول الحر: https://doaj.org/article/3e1635e644aa4013ac0fd350e9776b60Test

المؤلفون: Chung, Sook Hyun, Sin, Tzu-Ni, Dang, Brian, Ngo, Taylor, Lo, Therlinder, Lent-Schochet, Daniella, Meleppat, Ratheesh K, Zawadzki, Robert J, Yiu, Glenn

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Human Genome, Biotechnology, Neurodegenerative, Eye Disease and Disorders of Vision, Neurosciences, Aging, Genetics, Macular Degeneration, Aetiology, 2.1 Biological and endogenous factors, AAV, AMD, CRISPR, CRISPR-Cas9, GUIDE-seq, MT: RNA/DNA Editing, gene editing, neovascular AMD, ocular gene therapy, retinal gene therapy, Clinical Sciences, Biochemistry and cell biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5s36q0jsTest
https://escholarship.org/content/qt5s36q0js/qt5s36q0js.pdfTest

المؤلفون: Cheng, Shun-Yun, Punzo, Claudio

المساهمون: Horae Gene Therapy Center, Neurobiology, Ophthalmology and Visual Sciences

المصدر: Human gene therapy ; 33 ; 17-18 ; 865 ; 878 ; United States

مصطلحات موضوعية: clinical trials, retinal degeneration, retinal gene therapy

العلاقة: Human Gene Therapy; https://doi.org/10.1089/hum.2022.159Test; Cheng SY, Punzo C. Update on Viral Gene Therapy Clinical Trials for Retinal Diseases. Hum Gene Ther. 2022 Sep;33(17-18):865-878. doi:10.1089/hum.2022.159. PMID: 36074935; PMCID: PMC9639220.; http://hdl.handle.net/20.500.14038/53014Test

الإتاحة: https://doi.org/10.1089/hum.2022.159Test
https://doi.org/20.500.14038/53014Test
https://hdl.handle.net/20.500.14038/53014Test

المؤلفون: Haldrup, Silja Hansen, Fabian-Jessing, Bjørn K., Jakobsen, Thomas Stax, Lindholm, Anna Bøgh, Adsersen, Rikke L., Aagaard, Lars, Bek, Toke, Askou, Anne Louise, Corydon, Thomas J.

المصدر: Haldrup , S H , Fabian-Jessing , B K , Jakobsen , T S , Lindholm , A B , Adsersen , R L , Aagaard , L , Bek , T , Askou , A L & Corydon , T J 2024 , ' Subretinal AAV delivery of RNAi-therapeutics targeting VEGFA reduces choroidal neovascularization in a large animal model ' , Molecular Therapy Methods and Clinical Development , vol. 32 , no. 2 , 101242 . https://doi.org/10.1016/j.omtm.2024.101242Test

مصطلحات موضوعية: AAV, AMD, anti-VEGF, CNV, large animal model, miR-agshRNA, pig, retinal gene therapy, RNAi therapeutics

العلاقة: https://pure.au.dk/portal/en/publications/5b7e33f5-d0d2-456e-bcb1-c4efee1b41d4Test

الإتاحة: https://doi.org/10.1016/j.omtm.2024.101242Test
https://pure.au.dk/portal/en/publications/5b7e33f5-d0d2-456e-bcb1-c4efee1b41d4Test

المؤلفون: Ail D, Malki H, Zin EA, Dalkara D

المصدر: The Application of Clinical Genetics, Vol Volume 16, Pp 111-130 (2023)

مصطلحات موضوعية: retinal gene therapy, adeno-associated virus, aav, clinical trials, capsid variants, immune responses, Medicine (General), R5-920, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/adeno-associated-virus-aav---basedTest-gene-therapies-for-retinal-diseases-peer-reviewed-fulltext-article-TACG; https://doaj.org/toc/1178-704XTest

الوصول الحر: https://doaj.org/article/910618d2e5cb474f8263972d1c81961cTest

المؤلفون: Ashtari M, Lipin M, Duong M, Ying GS, Yu Y, Maguire A, Bennett J

المصدر: Eye and Brain, Vol Volume 14, Pp 137-147 (2022)

مصطلحات موضوعية: brain plasticity, retinal gene therapy, lateral geniculate nucleus, image processing, brain morphometry, Ophthalmology, RE1-994, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/neuroplasticity-of-the-lateral-geniculate-nucleus-in-response-to-retin-peer-reviewed-fulltext-article-EBTest; https://doaj.org/toc/1179-2744Test

الوصول الحر: https://doaj.org/article/dd9d2eb5ba254bfaa6f08045585d0cdaTest

المؤلفون: Yiu, Glenn, Chung, Sook Hyun, Mollhoff, Iris N, Nguyen, Uyen Tu, Thomasy, Sara M, Yoo, Jesse, Taraborelli, Donna, Noronha, Glenn

مصطلحات موضوعية: Medical Biotechnology, Biomedical and Clinical Sciences, Ophthalmology and Optometry, Gene Therapy, Eye Disease and Disorders of Vision, Neurosciences, Genetics, Biotechnology, Inflammatory and immune system, Eye, AAV, gene therapy, microneedles, nonhuman primate, retina, retinal gene therapy, rhesus macaques, suprachoroidal, suprachoroidal delivery, Medical biotechnology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7n23j55jTest

المؤلفون: Manzar Ashtari, Philip Cook, Mikhail Lipin, Yinxi Yu, Gui-Shuang Ying, Albert Maguire, Jean Bennett, James Gee, Hui Zhang

المصدر: Current Research in Neurobiology, Vol 4, Iss , Pp 100089- (2023)

مصطلحات موضوعية: Visual system, Brain plasticity, Myeline thinning, Dendritic sprouting, Retinal gene therapy, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2665945X23000177Test; https://doaj.org/toc/2665-945XTest

الوصول الحر: https://doaj.org/article/53fc31047aaf4981ab917f35a29449d2Test

المؤلفون: Maclaren, Robert E., Fischer, M. Dominik, Gow, James A., Lam, Byron L., Sankila, Eeva-Marja K., Girach, Aniz, Panda, Sushil, Yoon, Dan, Zhao, Guolin, Pennesi, Mark E.

المساهمون: HUS Head and Neck Center, Silmäklinikka

مصطلحات موضوعية: Retinal gene-therapy, Natural-history, Expression, Inclusion, Delivery, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: Maclaren , R E , Fischer , M D , Gow , J A , Lam , B L , Sankila , E-M K , Girach , A , Panda , S , Yoon , D , Zhao , G & Pennesi , M E 2023 , ' Subretinal timrepigene emparvovec in adult men with choroideremia : a randomized phase 3 trial ' , Nature Medicine , vol. 29 , no. 10 , pp. 2464–2472 . https://doi.org/10.1038/s41591-023-02520-3Test; http://hdl.handle.net/10138/567217Test; 743a91d7-83d1-40d5-bad4-3779bd72d57e; 001085417800001

الإتاحة: http://hdl.handle.net/10138/567217Test

المؤلفون: Ashtari, Manzar, Cook, Philip, Lipin, Mikhail, Yu, Yinxi, Ying, Gui-Shuang, Maguire, Albert, Bennett, Jean, Gee, James, Zhang, Hui

المصدر: Current Research in Neurobiology , 4 , Article 100089. (2023)

مصطلحات موضوعية: Brain plasticity, Dendritic sprouting, Myeline thinning, Retinal gene therapy, Visual system

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/10172910/1/1-s2.0-S2665945X23000177-main.pdfTest; https://discovery.ucl.ac.uk/id/eprint/10172910Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/10172910/1/1-s2.0-S2665945X23000177-main.pdfTest
https://discovery.ucl.ac.uk/id/eprint/10172910Test/