دورية أكاديمية
G‑Protein Coupled Receptor Gpr‑1 Is Important for the Growth and Nutritional Metabolism of an Invasive Bark Beetle Symbiont Fungi Leptographium procerum
| العنوان: | G‑Protein Coupled Receptor Gpr‑1 Is Important for the Growth and Nutritional Metabolism of an Invasive Bark Beetle Symbiont Fungi Leptographium procerum |
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| المؤلفون: | Fangyuan Ye, Zhiwei Kang, Hongru Kou, Yunwen Yang, Wei Chen, Saige Wang, Jianghua Sun, Fanghua Liu |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Biochemistry, Microbiology, Cell Biology, Genetics, Ecology, Developmental Biology, Cancer, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, red turpentine beetle, destructive invasive pests, thicker cell wall, rtb ), one, previous studies found, play important roles, procerum invasive complex, induced carbohydrate metabolism, leptographium procerum <, cell wall, leptographium procerum, invasive success, nutritional metabolism, 1 <, significantly inhibited, results indicated, potential applications, perturbing agents, lipid metabolisms |
| الوصف: | Leptographium procerum has been demonstrated to play important roles in the invasive success of red turpentine beetle (RTB), one of the most destructive invasive pests in China. Our previous studies found that bacterial volatile ammonia plays an important role in the maintenance of the RTB-L. procerum invasive complex. In this study, we found a GPCR gene Gpr-1 that was a response to ammonia but not involved in the ammonia-induced carbohydrate metabolism. Deletion of Gpr-1 significantly inhibited the growth and pathogenicity but thickened the cell wall of L. procerum, resulting in more resistance to cell wall-perturbing agents. Further analyses suggested that Gpr-1 deletion caused growth defects that might be due to the dysregulation of the amino acid and lipid metabolisms. The thicker cell wall in the Δ Gpr-1 mutant was induced through the cell wall remodeling process. Our results indicated that Gpr-1 is essential for the growth of L. procerum by regulating the nutritional metabolism, which can be further explored for potential applications in the management of RTB. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | https://figshare.com/articles/journal_contribution/G_Protein_Coupled_Receptor_i_Gpr_1_i_Is_Important_for_the_Growth_and_Nutritional_Metabolism_of_an_Invasive_Bark_Beetle_Symbiont_Fungi_i_Leptographium_procerum_i_/25012604Test |
| DOI: | 10.1021/acs.jafc.3c07547.s001 |
| الإتاحة: | https://doi.org/10.1021/acs.jafc.3c07547.s001Test https://figshare.com/articles/journal_contribution/G_Protein_Coupled_Receptor_i_Gpr_1_i_Is_Important_for_the_Growth_and_Nutritional_Metabolism_of_an_Invasive_Bark_Beetle_Symbiont_Fungi_i_Leptographium_procerum_i_/25012604Test |
| حقوق: | CC BY-NC 4.0 |
| رقم الانضمام: | edsbas.4E74D7D0 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1021/acs.jafc.3c07547.s001 |
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