المؤلفون: Robert Wodtke, Markus Laube, Sandra Hauser, Sebastian Meister, Friedrich-Alexander Ludwig, Steffen Fischer, Klaus Kopka, Jens Pietzsch, Reik Löser

مصطلحات موضوعية: Biochemistry, Medicine, Molecular Biology, Physiology, Pharmacology, Biotechnology, Cancer, Space Science, Chemical Sciences not elsewhere classified, Biodistribution, Defluorination, Drug metabolism, Fluorine-18 chemistry, PET imaging, Pharmacokinetics, Plasma clearance

العلاقة: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Preclinical_evaluation_of_an_18F-labeled_N_-acryloyllysine_piperazide_for_covalent_targeting_of_transglutaminase_2/24934192Test

الإتاحة: https://doi.org/10.6084/m9.figshare.24934192.v1Test
https://figshare.com/articles/journal_contribution/Additional_file_1_of_Preclinical_evaluation_of_an_18F-labeled_N_-acryloyllysine_piperazide_for_covalent_targeting_of_transglutaminase_2/24934192Test

المؤلفون: Raya Stoyanova (14322613), Paul Maximilian Katzberger (14322616), Leonid Komissarov (10798712), Aous Khadhraoui (14322619), Lisa Sach-Peltason (1747699), Katrin Groebke Zbinden (14322622), Torsten Schindler (3013920), Nenad Manevski (276406)

مصطلحات موضوعية: Biochemistry, Genetics, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Information Systems not elsewhere classified, gaussian process regressor, drug design stage, chemical structure alone, average fold error, ten machine learning, including plasma clearance, chemprop neural networks, discovery data set, data set sizes, 98 – 1, 96 – 2, 45 – 1, 35 – 2, computed prediction variance, shapley additive explanations, emphasized human interpretability, e ., pretraining, combined results show, rat pk studies, transfer learning approaches, higher overprediction bias, best aafe values, clp ), volume

العلاقة: https://figshare.com/articles/journal_contribution/Computational_Predictions_of_Nonclinical_Pharmacokinetics_at_the_Drug_Design_Stage/21809572Test

الإتاحة: https://doi.org/10.1021/acs.jcim.2c01134.s001Test

المؤلفون: Andrey G. Sarafanov

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8584

مصطلحات موضوعية: hemophilia A, factor VIII, von Willebrand factor, therapeutic factor VIII, extended half-life factor VIII, plasma clearance, clearance receptors, low-density lipoprotein receptor-related protein 1, efanesoctocog alfa, activity assays discrepancy

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Genetics and Genomics; https://dx.doi.org/10.3390/ijms24108584Test

الإتاحة: https://doi.org/10.3390/ijms24108584Test

المؤلفون: Hans Pottel, Elke Schaeffner, Natalie Ebert, Markus van der Giet, Pierre Delanaye

المصدر: BMC Nephrology, Vol 22, Iss 1, Pp 1-8 (2021)

مصطلحات موضوعية: Iohexol plasma clearance, Multiple samples, One sample, Measured GFR, Diseases of the genitourinary system. Urology, RC870-923

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1471-2369Test

الوصول الحر: https://doaj.org/article/31ed9366475447828491b16374855fddTest

المؤلفون: Kelly N. Monaghan, Mary Anna Labato, Mark G. Papich

المصدر: Journal of Veterinary Internal Medicine, Vol 35, Iss 2, Pp 987-992 (2021)

مصطلحات موضوعية: acute kidney injury, drug concentration, half‐life, plasma clearance, volume of distribution, Veterinary medicine, SF600-1100

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/0891-6640Test; https://doaj.org/toc/1939-1676Test

الوصول الحر: https://doaj.org/article/b4720bb897dc48dea67a269bf85f9179Test

المؤلفون: Kågedal, Bertil, Mandenius, Carl-Fredrik

المصدر: Clin Chim Acta ; ISSN:1873-3492 ; Volume:561

مصطلحات موضوعية: Distribution to extracellular spaces, Glomerular filtration rate, Iohexol, Iohexol plasma clearance, Mass balance modelling

العلاقة: https://doi.org/10.1016/j.cca.2024.119823Test; https://pubmed.ncbi.nlm.nih.gov/38917869Test

الإتاحة: https://doi.org/10.1016/j.cca.2024.119823Test
https://pubmed.ncbi.nlm.nih.gov/38917869Test

المؤلفون: Hiroshi Hosoda, Tsutomu Nakamura, Fumiki Yoshihara

المصدر: Biomolecules; Volume 12; Issue 9; Pages: 1281

مصطلحات موضوعية: adrenomedullin, plasma clearance, calcitonin receptor-like receptor, receptor activity modifying proteins, kidney

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Medicine; https://dx.doi.org/10.3390/biom12091281Test

الإتاحة: https://doi.org/10.3390/biom12091281Test

المؤلفون: Seals, Ryan, Bartell, Scott M, Steenland, Kyle

المصدر: Environmental health perspectives. 119(1)

مصطلحات موضوعية: Adult, Aged, Caprylates: analysis, blood, Environmental Exposure: analysis, statistics & numerical data, Environmental Monitoring, Female, Fluorocarbons: analysis, blood, Half-Life, Humans, Male, Middle Aged, Models, Biological, Ohio, Questionnaires, Residence Characteristics: statistics & numerical data, Water Pollutants, Chemical: analysis, blood, Water Supply: analysis, West Virginia, Young Adult, C8, Half-life, Pfa, Pfoa, Serum levels, Water contaminationperfluorooctanoic acid, adult, article, bioaccumulation, blood level, concentration (parameters), environmental exposure, female, human, male, plasma clearance, plasma half life, pollution monitoring, priority journal, residential area, United States, water contamination, Adult, Aged, Environmental Exposure, Environmental Monitoring, Female, Fluorocarbons, Half-Life, Humans, Male, Middle Aged, Models, Biological, Octanoic Acids, Ohio, Questionnaires, Residence Characteristics, Water Pollutants, Chemical, Water Supply, West Virginia, Young Adult, Adult, Aged, Caprylates: analysis, blood, Environmental Exposure: analysis, statistics & numerical data, Environmental Monitoring, Female, Fluorocarbons: analysis, blood, Half-Life, Humans, Male, Middle Aged, Models, Biological, Ohio, Questionnaires, Residence Characteristics: statistics & numerical data, Water Pollutants, Chemical: analysis, blood, Water Supply: analysis, West Virginia, Young Adult, C8, Half-life, Pfa, Pfoa, Serum levels, Water contaminationperfluorooctanoic acid, adult, article, bioaccumulation, blood level, concentration (parameters), environmental exposure, female, human, male, plasma clearance, plasma half life, pollution monitoring, priority journal, residential area, United States, water contamination, Adult, Aged, Environmental Exposure, Environmental Monitoring, Female, Fluorocarbons, Half-Life, Humans, Male, Middle Aged, Models, Biological, Octanoic Acids, Ohio, Questionnaires, Residence Characteristics, Water Pollutants, Chemical, Water Supply, West Virginia, Young Adult

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/79j411dtTest

المؤلفون: Sarah Baklouti, Didier Concordet, Vitaliano Borromeo, Paola Pocar, Paola Scarpa, Petra Cagnardi

المصدر: Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: dog, population pharmacokinetic, iohexol plasma clearance, sampling time optimization, glomerular filtration rate estimation, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2021.634404/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/a69da1d7a30e4145b05223375844061dTest

المؤلفون: van Gelder, Maaike K, Stevens, Jasper, Pieters, Tobias T, Vaessen, Koen R D, Joles, Jaap A, Verhaar, Marianne C, Gerritsen, Karin G F

المساهمون: Nefro Vasculaire Geneeskunde, MS Nefrologie, Circulatory Health, Regenerative Medicine and Stem Cells

مصطلحات موضوعية: Chronic kidney disease, Glomerular filtration rate, Goat, Iohexol, Plasma clearance, Uremic animal model, General Agricultural and Biological Sciences, General Biochemistry,Genetics and Molecular Biology, General Immunology and Microbiology, Journal Article

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/442905Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/442905Test