دورية أكاديمية
High Myoinositol on Proton MR Spectroscopy Could Be a Potential Signature of Papillary Tumors of the Pineal Region—Case Report of Two Patients
| العنوان: | High Myoinositol on Proton MR Spectroscopy Could Be a Potential Signature of Papillary Tumors of the Pineal Region—Case Report of Two Patients |
|---|---|
| المؤلفون: | Albert Pons-Escoda, Juan Jose Sánchez Fernández, Àlex de Vilalta, Noemí Vidal, Carles Majós |
| المصدر: | Brain Sciences, Vol 12, Iss 802, p 802 (2022) |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | pineal neoplasms, differential diagnosis, NMR spectroscopy, myoinositol, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| الوصف: | Papillary tumor of the pineal region (PTPR) is an uncommon entity in which a presurgical suspicion may be crucial for patient management. Maximal safe neurosurgical resection is of choice when PTPR is suspected, whereas non-surgical approaches can be considered in other tumors of the pineal region, such as pineocytoma or concrete subtypes of germ-cell tumors. In general terms, imaging features of tumors of the pineal region have been reported to be unspecific. Nevertheless, in this report, we describe two pathology-confirmed PTPRs in which presurgical proton MR spectroscopy demonstrated extremely high myoinositol, a pattern which drastically differs from that of other pineal tumors. We hypothesize that this high myoinositol may be related to PTPR’s known ependymal component, and that it could be used as a specific non-invasive diagnostic signature. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2076-3425 |
| العلاقة: | https://www.mdpi.com/2076-3425/12/6/802Test; https://doaj.org/toc/2076-3425Test; https://doaj.org/article/1242b5976dc144cd9bd30f173c56e478Test |
| DOI: | 10.3390/brainsci12060802 |
| الإتاحة: | https://doi.org/10.3390/brainsci12060802Test https://doaj.org/article/1242b5976dc144cd9bd30f173c56e478Test |
| رقم الانضمام: | edsbas.F0646FF5 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20763425 |
|---|---|
| DOI: | 10.3390/brainsci12060802 |