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المؤلفون: Anna Behler, Hans-Peter Müller, Albert C. Ludolph, Jan Kassubek
المصدر: International journal of molecular sciences 24(3), 1911 (2023). doi:10.3390/ijms24031911
مصطلحات موضوعية: amyotrophic lateral sclerosis, Organic Chemistry, General Medicine, artificial intelligence, diffusion tensor imaging, Catalysis, methods [Diffusion Tensor Imaging], Computer Science Applications, Inorganic Chemistry, Machine Learning, ddc:540, motor neuron disease, Humans, magnetic resonance imaging, Physical and Theoretical Chemistry, pathology [Amyotrophic Lateral Sclerosis], Molecular Biology, Spectroscopy, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa59f867076f075d9b855fcb87e332aTest
https://pub.dzne.de/record/253605Test -
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المؤلفون: Peter T. Nelson, Edward B. Lee, Matthew D. Cykowski, Irina Alafuzoff, Konstantinos Arfanakis, Johannes Attems, Carol Brayne, Maria M. Corrada, Brittany N. Dugger, Margaret E. Flanagan, Bernardino Ghetti, Lea T. Grinberg, Murray Grossman, Michel J. Grothe, Glenda M. Halliday, Masato Hasegawa, Suvi R. K. Hokkanen, Sally Hunter, Kurt Jellinger, Claudia H. Kawas, C. Dirk Keene, Naomi Kouri, Gabor G. Kovacs, James B. Leverenz, Caitlin S. Latimer, Ian R. Mackenzie, Qinwen Mao, Kirsty E. McAleese, Richard Merrick, Thomas J. Montine, Melissa E. Murray, Liisa Myllykangas, Sukriti Nag, Janna H. Neltner, Kathy L. Newell, Robert A. Rissman, Yuko Saito, S. Ahmad Sajjadi, Katherine E. Schwetye, Andrew F. Teich, Dietmar R. Thal, Sandra O. Tomé, Juan C. Troncoso, Shih-Hsiu J. Wang, Charles L. White, Thomas Wisniewski, Hyun-Sik Yang, Julie A. Schneider, Dennis W. Dickson, Manuela Neumann
المساهمون: University of Helsinki, Department of Pathology, HUSLAB, Apollo - University of Cambridge Repository
المصدر: Acta neuropathologica 145(2), 159-173 (2023). doi:10.1007/s00401-022-02524-2
مصطلحات موضوعية: Aging, TDP-43, genetics [DNA-Binding Proteins], 3124 Neurology and psychiatry, Pathology and Forensic Medicine, pathology [Alzheimer Disease], Cellular and Molecular Neuroscience, Alzheimer Disease, Stages, Humans, ddc:610, pathology [Amyotrophic Lateral Sclerosis], Amyotrophic Lateral Sclerosis, 3112 Neurosciences, FTD, NCI, Processes, DNA-Binding Proteins, Neuroanatomy, Frontotemporal Dementia, pathology [Frontotemporal Dementia], Hippocampal sclerosis, Dementia, 3111 Biomedicine, Neurology (clinical)
وصف الملف: application/pdf; text/xml; Print-Electronic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72494332571ed755e236f6b2d683266Test
https://pubmed.ncbi.nlm.nih.gov/36512061Test -
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المؤلفون: Tobias M. Böckers, Albert C. Ludolph, Jan Kassubek, David Bayer, Luc Dupuis, Hans-Peter Müller, Stefano Antonucci, Volker Rasche, Rami Saad, Francesco Roselli
المساهمون: University of Ulm (UUlm), Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Dieterle, Stéphane
المصدر: Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-17 (2021)
Translational Neurodegeneration
Translational Neurodegeneration, [London] : BioMed Central, 2012-, 2021, 10 (1), pp.17. ⟨10.1186/s40035-021-00241-6⟩
Translational Neurodegeneration, 2021, 10 (1), pp.17. ⟨10.1186/s40035-021-00241-6⟩
Translational neurodegeneration 10(1), 17 (2021). doi:10.1186/s40035-021-00241-6مصطلحات موضوعية: 0301 basic medicine, Lateral hypothalamus, [SDV]Life Sciences [q-bio], Cohort Studies, Mice, 0302 clinical medicine, Superoxide Dismutase-1, diagnostic imaging [Amyotrophic Lateral Sclerosis], Neural Pathways, Amyotrophic lateral sclerosis, Brain Mapping, pathology [Motor Cortex], Motor Cortex, diagnostic imaging [Hypothalamus], pathology [Neural Pathways], Immunohistochemistry, diagnostic imaging [Neural Pathways], genetics [Superoxide Dismutase-1], [SDV] Life Sciences [q-bio], medicine.anatomical_structure, Diffusion Tensor Imaging, diagnostic imaging [Prefrontal Cortex], Motor cortex, Hypermetabolism, Cognitive Neuroscience, SOD1, Hypothalamus, Prefrontal Cortex, Biology, pathology [Hypothalamus], 03 medical and health sciences, Cellular and Molecular Neuroscience, ddc:570, rAAV2, medicine, Orbitofrontal cortex, Animals, Humans, pathology [Amyotrophic Lateral Sclerosis], RC346-429, Research, medicine.disease, Agranular insula, pathology [Prefrontal Cortex], 030104 developmental biology, Case-Control Studies, Forebrain, RNA-Binding Protein FUS, Neurology (clinical), Neurology. Diseases of the nervous system, Energy Metabolism, Neuroscience, Insula, genetics [RNA-Binding Protein FUS], 030217 neurology & neurosurgery, growth & development [Motor Cortex]
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975db4967a8ff48ee26982bd77308f6eTest
https://doaj.org/article/a6593394dc8947b5b66f4a710304a553Test -
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المؤلفون: Jennie Olofsson, Peter Lönnerberg, Caroline Ingre, Elena Rodriguez-Vieitez, Inci Sevval Aksoylu, Caroline Mijnsbergen, Manuela Lehmann, Jan H. Veldink, Inti von Gohren Antequera, Albert C. Ludolph, Anna Szczepińska, Stefan Wouters, Mathias Uhlén, Ulf Kläppe, Eleonora Aronica, Hermieneke Vergunst-Bosch, Anna Månberg, Julia Remnestål, Sebastian A. Lewandowski, Lwaki Ebarasi, Peter Nilsson, Aylin Domaniku, Robert A. Harris, Nathan G. Skene, Jasper J. Anink, Joke De Vocht, Eva Hedlund, Annemarie Hübers, Koen Poesen, Philip Van Damme, Marta Trusohamn, Jonathan D. Gilthorpe, Maxim De Schaepdryver, Folkert Sanders
المساهمون: Pathology, APH - Aging & Later Life, APH - Mental Health, ANS - Cellular & Molecular Mechanisms
المصدر: Nature medicine, 27(4), 640-646. Nature Publishing Group
Nat Med
Nature medicine 27(4), 640-646 (2021). doi:10.1038/s41591-021-01295-9مصطلحات موضوعية: 0301 basic medicine, Pathology, Transcription, Genetic, Cell, blood [Osteopontin], Disease, blood [Amyotrophic Lateral Sclerosis], Superoxide Dismutase-1, 0302 clinical medicine, Cerebrospinal fluid, genetics [Superoxide Dismutase], Medicine, SPP1 protein, human, Perivascular space, Amyotrophic lateral sclerosis, 11 Medical and Health Sciences, physiopathology [Amyotrophic Lateral Sclerosis], General Medicine, Prognosis, Col6a1 protein, human, DNA-Binding Proteins, genetics [Amyotrophic Lateral Sclerosis], medicine.anatomical_structure, Spinal Cord, 030220 oncology & carcinogenesis, metabolism [Collagen Type VI], Disease Progression, metabolism [DNA-Binding Proteins], pathology [Fibroblasts], metabolism [Biomarkers], Genetic Markers, pathology [Blood Vessels], medicine.medical_specialty, Neurofilament, genetics [Collagen Type VI], Immunology, Mice, Transgenic, pathology [Spinal Cord], Collagen Type VI, Vascular Remodeling, metabolism [RNA, Messenger], Article, General Biochemistry, Genetics and Molecular Biology, genetics [RNA, Messenger], 03 medical and health sciences, ultrastructure [Spinal Cord], Animals, Humans, ddc:610, RNA, Messenger, pathology [Amyotrophic Lateral Sclerosis], Fibroblast, Superoxide Dismutase, business.industry, Amyotrophic Lateral Sclerosis, Fibroblasts, Spinal cord, medicine.disease, 030104 developmental biology, Blood Vessels, Osteopontin, business, Biomarkers
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21731374f1cfb4720d18cbcff7cff41Test
https://doi.org/10.1038/s41591-021-01295-9Test -
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المؤلفون: Evelien Van Schoor, Simona Ospitalieri, Sebastiaan Moonen, Sandra O. Tomé, Alicja Ronisz, Orkun Ok, Jochen Weishaupt, Albert C. Ludolph, Philip Van Damme, Ludo Van Den Bosch, Dietmar Rudolf Thal
المصدر: Acta neuropathologica 144(3), 393-411 (2022). doi:10.1007/s00401-022-02466-9
مصطلحات موضوعية: metabolism [Motor Cortex], pathology [Motor Neurons], Inflammasomes, metabolism [NLR Family, Pyrin Domain-Containing 3 Protein], Mice, Transgenic, Pathology and Forensic Medicine, Inflammasome, Cellular and Molecular Neuroscience, Mice, Mice, Inbred NOD, pathology [White Matter], NLR Family, Pyrin Domain-Containing 3 Protein, Pyroptosis, Animals, Humans, ddc:610, pathology [Amyotrophic Lateral Sclerosis], Motor Neurons, Amyotrophic Lateral Sclerosis, Motor Cortex, pathology [Microglia], Amyotrophic lateral sclerosis, White Matter, Transactive response DNA-binding protein, DNA-Binding Proteins, Disease Models, Animal, Neurology (clinical), Microglia, metabolism [DNA-Binding Proteins], metabolism [Inflammasomes]
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3c53395a7b4e2afdc364d08dc754e8Test
https://pubmed.ncbi.nlm.nih.gov/35867112Test -
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المؤلفون: Francesca Paron, Petra Frick, Emanuele Buratti, Manuela Neumann, Jonas Kosten, Ian R. A. Mackenzie
المصدر: Acta neuropathologica 140(5), 645-658 (2020). doi:10.1007/s00401-020-02207-w
Acta Neuropathologica
Acta Neuropatholمصطلحات موضوعية: Male, metabolism [Inclusion Bodies], Phosphorylation-specific antibody, TDP-43, Protein Conformation, chemistry [Inclusion Bodies], medicine.disease_cause, Serine, pathology [Inclusion Bodies], 0302 clinical medicine, C9orf72, Conformation-specific, Phosphorylation, Inclusion Bodies, Aged, 80 and over, 0303 health sciences, Mutation, Frontotemporal lobar degeneration, Middle Aged, Phenotype, DNA-Binding Proteins, metabolism [Frontotemporal Dementia], Immunohistochemistry, Female, metabolism [DNA-Binding Proteins], Frontotemporal dementia, Biology, Protein Aggregation, Pathological, Pathology and Forensic Medicine, Protein Aggregates, 03 medical and health sciences, Cellular and Molecular Neuroscience, metabolism [Protein Aggregation, Pathological], mental disorders, medicine, Humans, ddc:610, pathology [Amyotrophic Lateral Sclerosis], Aged, 030304 developmental biology, Antiserum, Original Paper, metabolism [Amyotrophic Lateral Sclerosis], Amyotrophic Lateral Sclerosis, Correction, nutritional and metabolic diseases, chemistry [DNA-Binding Proteins], medicine.disease, Molecular biology, nervous system diseases, TDP-43 strains, pathology [Frontotemporal Dementia], Neurology (clinical), ALS, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c29d80fd30a68adda7f25fdac22f99Test
https://doi.org/10.1007/s00401-020-02207-wTest -
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المؤلفون: Florian Wegner, Selma Staege, Andreas Hermann, Stefan Stefanov, Hannes Glass, Susanne Petri, Dieter Edbauer, Rajat Bhatnagar, Antje Janosch, Petra Freitag, Anne-Karin Kahlert, Marc Bickle, Jared Sterneckert, Tanja Richter, Arun Pal, Carina Schludi, Walter Just, Norman Kalmbach, Masin Abo-Rady
المصدر: Stem Cell Reports, Vol 14, Iss 3, Pp 390-405 (2020)
Stem Cell Reports
Stem cell reports 14(3), 390-405 (2020). doi:10.1016/j.stemcr.2020.01.010مصطلحات موضوعية: 0301 basic medicine, amyotrophic lateral sclerosis, genetics [Transcriptome], Apoptosis, metabolism [Axons], Biochemistry, genetics [Gain of Function Mutation], Pathogenesis, metabolism [HSP40 Heat-Shock Proteins], Gene Knockout Techniques, 0302 clinical medicine, C9orf72, disease modeling, Axon, Amyotrophic lateral sclerosis, drug effects [Axons], drug effects [Motor Neurons], Induced pluripotent stem cell, lcsh:QH301-705.5, HSP70, pharmacology [Pyrrolidinones], Motor Neurons, lcsh:R5-920, DNA Repeat Expansion, drug effects [Induced Pluripotent Stem Cells], gene editing, drug effects [Cell Differentiation], pathology [Nerve Degeneration], Cell Differentiation, Pyrrolidinones, Cell biology, metabolism [Induced Pluripotent Stem Cells], genetics [Amyotrophic Lateral Sclerosis], medicine.anatomical_structure, metabolism [C9orf72 Protein], Gain of Function Mutation, lcsh:Medicine (General), pathology [Motor Neurons], induced pluripotent stem cells, metabolism [HSP70 Heat-Shock Proteins], genetics [DNA Repeat Expansion], C9ORF72, axonal trafficking, drug effects [Apoptosis], Biology, Cytoplasmic Granules, Models, Biological, Article, 03 medical and health sciences, Heat shock protein, Genetics, medicine, Humans, pharmacology [Benzhydryl Compounds], HSP70 Heat-Shock Proteins, ddc:610, Benzhydryl Compounds, pathology [Amyotrophic Lateral Sclerosis], genetics [C9orf72 Protein], C9orf72 Protein, metabolism [Motor Neurons], Cell Biology, HSP40 Heat-Shock Proteins, medicine.disease, metabolism [Cytoplasmic Granules], Axons, Hsp70, 030104 developmental biology, drug effects [Cytoplasmic Granules], HSP40, lcsh:Biology (General), heat shock proteins, Nerve Degeneration, Transcriptome, Trinucleotide repeat expansion, 030217 neurology & neurosurgery, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e36d802ed14d96d26a9814e300c2698Test
http://www.sciencedirect.com/science/article/pii/S221367112030031XTest -
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المؤلفون: Hanna Glasebach, Friederike Hans, Philipp J. Kahle
المصدر: The journal of biological chemistry 295(3), 673-689 (2019). doi:10.1074/jbc.RA119.010617
J Biol Chemمصطلحات موضوعية: Indoles, drug effects [Solubility], Protein aggregation, Biochemistry, Ubiquitin, genetics [Heat-Shock Proteins], GSK-3, genetics [Oxidative Stress], Sorbitol, genetics [Ubiquitination], genetics [Frontotemporal Dementia], Heat-Shock Proteins, biology, Kinase, Chemistry, drug effects [Osmotic Pressure], pharmacology [Acetylcysteine], Molecular Bases of Disease, Cell biology, DNA-Binding Proteins, drug effects [Mutation], Protein Transport, genetics [Amyotrophic Lateral Sclerosis], Frontotemporal Dementia, genetics [Protein Transport], Signal transduction, analogs & derivatives [Adenine], Signal Transduction, drug effects [Signal Transduction], genetics [DNA-Binding Proteins], pharmacology [Indoles], Protein Aggregation, Pathological, Stress granule, Osmotic Pressure, mental disorders, pharmacology [Adenine], Humans, genetics [Protein Aggregation, Pathological], genetics [Glycogen Synthase Kinase 3 beta], ddc:610, Protein kinase A, pathology [Amyotrophic Lateral Sclerosis], Molecular Biology, Glycogen Synthase Kinase 3 beta, Adenine, Endoplasmic reticulum, pharmacology [Sorbitol], Amyotrophic Lateral Sclerosis, Ubiquitination, nutritional and metabolic diseases, Cell Biology, chemistry [DNA-Binding Proteins], Acetylcysteine, nervous system diseases, Oxidative Stress, HEK293 Cells, Solubility, Mutation, pathology [Frontotemporal Dementia], biology.protein, chemistry [Heat-Shock Proteins]
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aeb0acdf72640fe456c545974eb3808Test
https://doi.org/10.1016/s0021-9258Test(17)49926-1 -
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المؤلفون: Hans-Peter Müller, Kelly Del Tredici, Jan Kassubek, Hans-Jürgen Huppertz, Heiko Braak, Albert C. Ludolph, Angela Rosenbohm
المصدر: Journal of neurology 269(5), 2619-2626 (2021). doi:10.1007/s00415-021-10854-6
مصطلحات موضوعية: medicine.medical_specialty, Neurology, diagnostic imaging [Arm], Pyramidal Tracts, methods [Diffusion Tensor Imaging], White matter, Magnetic resonance imaging, Atrophy, diagnostic imaging [Amyotrophic Lateral Sclerosis], methods [Image Processing, Computer-Assisted], Fractional anisotropy, medicine, Image Processing, Computer-Assisted, Humans, ddc:610, Motor neuron disease, Vascular Diseases, Amyotrophic lateral sclerosis, pathology [Amyotrophic Lateral Sclerosis], Flail arm syndrome, Neuroradiology, Brain Mapping, medicine.diagnostic_test, business.industry, Amyotrophic Lateral Sclerosis, pathology [Arm], Anatomy, medicine.disease, Diffusion tensor imaging, medicine.anatomical_structure, Diffusion Tensor Imaging, complications [Amyotrophic Lateral Sclerosis], Arm, Disease Progression, Anisotropy, Neurology (clinical), business, Diffusion MRI
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa37d8f73c46fb026189349b53dd559eTest
https://pubmed.ncbi.nlm.nih.gov/34676447Test -
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المؤلفون: Jin, Mengmeng, Akgün, Katja, Ziemssen, Tjalf, Kipp, Markus, Günther, René, Hermann, Andreas
المصدر: International Journal of Molecular Sciences, Vol 22, Iss 8042, p 8042 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 15
International journal of molecular sciences 22(15), 8042 (2021). doi:10.3390/ijms22158042 special issue: "The Mechanisms Regulation of the Neuromuscular Dysfunctions"مصطلحات موضوعية: amyotrophic lateral sclerosis, pathology [Motor Neurons], Cell Survival, induced pluripotent stem cells, QH301-705.5, IL17F protein, human, immunology [Amyotrophic Lateral Sclerosis], IL17A protein, human, multiple sclerosis, Article, interleukin-17, immunology [RNA-Binding Protein FUS], fused in sarcoma, Humans, Biology (General), pathology [Amyotrophic Lateral Sclerosis], motor neuron, QD1-999, Motor Neurons, Th17 cell, immunology [Induced Pluripotent Stem Cells], immunology [Cell Survival], neurodegeneration, FUS protein, human, pathology [Induced Pluripotent Stem Cells], immunology [Th17 Cells], Chemistry, immunology [Interleukin-17], ddc:540, RNA-Binding Protein FUS, Th17 Cells, immunology [Motor Neurons], pathology [Th17 Cells]
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e97a16541ebba52bbb0737e22c38e0a4Test
https://www.mdpi.com/1422-0067/22/15/8042Test