المؤلفون: Häkkinen, Katja, Kiander, Wilma, Kidron, Heidi, Lähteenvuo, Markku, Urpa, Lea, Lintunen, Jonne, Vellonen, Kati-Sisko, Auriola, Seppo, Holm, Minna, Lahdensuo, Kaisla, Kampman, Olli, Isometsä, Erkki, Kieseppä, Tuula, Lönnqvist, Jouko, Suvisaari, Jaana, Hietala, Jarmo, Tiihonen, Jari, Palotie, Aarno, Ahola-Olli, Ari V., Niemi, Mikko

المصدر: Molecular Pharmaceutics. 20(3):1500-1508

مصطلحات موضوعية: drug transporter, OATP1B1, organic anion transporting polypeptide 1B1, pharmacogenetics, SLCO1B1

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-205358Test
https://doi.org/10.1021/acs.molpharmaceut.2c00715Test
https://umu.diva-portal.org/smash/get/diva2:1747506/FULLTEXT01.pdfTest

المؤلفون: Aleksey V. Shchulkin, Yulia V. Abalenikhina, Aleksandr A. Slepnev, Egor D. Rokunov, Elena N. Yakusheva

المصدر: Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9593-9605 (2023)

مصطلحات موضوعية: organic anion transporting polypeptide 1B1, estradiol, testosterone, progesterone, adopted orphan receptors, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1467-3045/45/12/600Test; https://doaj.org/toc/1467-3037Test; https://doaj.org/toc/1467-3045Test

الوصول الحر: https://doaj.org/article/ce89e97d2119492f961b846c0c9c851dTest

المؤلفون: Rika Ishikawa, Kosuke Saito, Takashi Misawa, Yosuke Demizu, Yoshiro Saito

المصدر: Biomolecules; Volume 13; Issue 6; Pages: 1002

مصطلحات موضوعية: ATSP-7041, MDM2/MDMX inhibitor, α-helical peptide, drug–drug interaction, organic anion transporting polypeptide 1B1

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Chemical Biology; https://dx.doi.org/10.3390/biom13061002Test

الإتاحة: https://doi.org/10.3390/biom13061002Test

المؤلفون: Katja Häkkinen, Wilma Kiander, Heidi Kidron, Markku Lähteenvuo, Lea Urpa, Jonne Lintunen, Kati-Sisko Vellonen, Seppo Auriola, Minna Holm, Kaisla Lahdensuo, Olli Kampman, Erkki Isometsä, Tuula Kieseppä, Jouko Lönnqvist, Jaana Suvisaari, Jarmo Hietala, Jari Tiihonen, Aarno Palotie, Ari V. Ahola-Olli, Mikko Niemi

المساهمون: Tampere University, Clinical Medicine, Department of Child Psychiatry

المصدر: Molecular Pharmaceutics. 20:1500-1508

مصطلحات موضوعية: 317 Pharmacy, Drug Discovery, OATP1B1, Pharmaceutical Science, Molecular Medicine, Pharmacology and Toxicology, Farmakologi och toxikologi, 3124 Neurology and psychiatry, drug transporter, SLCO1B1, organic anion transporting polypeptide 1B1, pharmacogenetics

وصف الملف: application/pdf; fulltext

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a93e8cfd6ae6cf7cd04c598bc0ca94dTest
https://doi.org/10.1021/acs.molpharmaceut.2c00715Test

المؤلفون: Daka Grapci A., Dimovski A. J., Kapedanovska A., Vavlukis M., Eftimov A., Matevska Geshkovska N., Labachevski N., Jakjovski K., Gorani D., Kedev S., Mladenovska Kristina

المصدر: Balkan Journal of Medical Genetics, Vol 18, Iss 1, Pp 5-22 (2015)

مصطلحات موضوعية: haplotypes, organic anion-transporting polypeptide 1b1 (oatp1b1), solute carrier organic anion-transporter family member 1b1 (slco1b1) gene, single nucleotide polymorphisms (snps), western balkan populations, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1311-0160Test

الوصول الحر: https://doaj.org/article/cb61f55a2b7e41bcb6f454df4ab29571Test

المؤلفون: Hiroaki Yamaguchi, Masahiro Okada, Shou Akitaya, Hiroshi Ohara, Tsuyoshi Mikkaichi, Haruna Ishikawa, Mayumi Sato, Masaki Matsuura, Toshihide Saga, Michiaki Unno, Takaaki Abe, Nariyasu Mano, Takanori Hishinuma, Junichi Goto

المصدر: Journal of Lipid Research, Vol 47, Iss 6, Pp 1196-1202 (2006)

مصطلحات موضوعية: nitrobenz-2-oxa-1,3-diazole, organic anion-transporting polypeptide 1B1, organic anion-transporting polypeptide 1B3, visualization, Biochemistry, QD415-436

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227520332181Test; https://doaj.org/toc/0022-2275Test

الوصول الحر: https://doaj.org/article/7cd49a37551f4293bc85b8f419793ab4Test

المؤلفون: Ken-ichi Fujita, Yukio Kato, Shinichi Iwai, Hiroo Ishida, Yutaro Kubota, Natsumi Matsumoto, Motoko Shibanuma

المصدر: Current Drug Metabolism

مصطلحات موضوعية: Renal failure, medicine.drug_class, Clinical Biochemistry, Tyrosine kinase inhibitor, Renal function, Antineoplastic Agents, Pharmacology, Drug-metabolizing enzyme, Transporter, Article, Tyrosine-kinase inhibitor, Pharmacokinetics, Non-renal clearance, medicine, Animals, Humans, Renal Insufficiency, Dosing, Adverse effect, Protein Kinase Inhibitors, business.industry, Organic-anion transporting polypeptide 1B1, Disposition, Cytotoxic anticancer drug, medicine.disease, Uremia, Liver, Systemic exposure, business, Tyrosine kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6158e7f48b4cf46a8ca4b32d4d552caTest
https://doi.org/10.2174/1389200220666190402143125Test

المؤلفون: Hirotoshi Ebinuma, Nobuhiro Nakamoto, Takanori Kanai, Yoshinori Horie, 中本 伸宏, 堀江 義則, 海老沼 浩利, 金井 隆典

المصدر: 肝臓 / Kanzo. 2015, 56(1):13

المؤلفون: Hiroki Ohya, Jiro Ogura, Katsuya Narumi, Ken Iseki, Masaki Kobayashi, Yoshihiko Shibayama

المصدر: Biological and Pharmaceutical Bulletin. 2015, 38(4):582

المؤلفون: Jian Lu, Xinrun Ma, Xin Wang, Xuan Qin, Mingyao Liu, Xuyang Shang

المصدر: Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 850-860 (2020)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: WT, wild type, Knockout rat, SLC, solute carrier, BUN, blood urea nitrogen, HMG, hydroxymethylglutaryl, PMSG, pregnant mare serum gonadotropin, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, Endogeny, GLB, globulin, AST, aspartate aminotransferase, DMSO, dimethyl sulfoxide, Rotor syndrome, IS, internal standard solution, HDL-C, high density lipoprotein cholesterol, chemistry.chemical_compound, 0302 clinical medicine, MC, methylcellulose, DDI, drug–drug interaction, HCG, human chorionic gonadotropin, TBL, total bilirubin, General Pharmacology, Toxicology and Pharmaceutics, AUC, the area under the time–plasma concentration curve, OATP1B1/3, organic anion transporting polypeptide 1B1 and 1B3, Chr, chromosome, p.o., peroral, TBA, total bile acid, 0303 health sciences, CL/F, clearance/bioavailability, ADRs, adverse drug reactions, A/G, albumin/globulin ratio, ZFN, zinc-finger nucleases, biology, TG, triglyceride, OATP1B2, OATPs, organic anion transporting polypeptides, GLU, glucose, HRP, horseradish peroxidase, TP, total protein, CR, reatinine, DBL, direct bilirubin, UA, uric acid, Organic anion-transporting polypeptide, Biochemistry, Cmax, peak concentration, CRISPR, clustered regularly interspaced short palindromic repeats, 030220 oncology & carcinogenesis, SNPs, single nucleotide polymorphisms, Rat model, R-GT, γ-glutamyltranspeptidase, MRT, mean residence time, NC, nitrocellulose, LDL-C, low density lipoprotein cholesterol, Vd/F, the apparent volume of distribution/bioavailability, medicine.drug, Original article, IBIL, indirect bilirubin, Bilirubin, crRNA, mature CRISPR RNA, Transporter, FDA, the U.S. Food and Drug Administration, TBST, Tris-buffered saline Tween 20, 03 medical and health sciences, Pharmacokinetics, OATP1B1/3, ALT, alanine aminotransferase, TALEN, transcription activator-like effector nuclease, medicine, PAM, protospacer adjacent motif, Tmax, peak time, Pitavastatin, ALB, albumin, CRISPR/Cas9, 030304 developmental biology, HE, haemotoxylin and eosin, KO, knockout, ALP, alkaline phosphatase, DAB, 3,3′-diaminobenzidine, lcsh:RM1-950, sgRNA, single guide RNA, T-CH, total cholesterol, medicine.disease, HZ, heterozygous, lcsh:Therapeutics. Pharmacology, chemistry, T7E I, T7 endonuclease I, SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis, biology.protein, SD, Sprague–Dawley, Ugt1a1, UDP glucuronosyltransferase family 1 member A1

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3274f81619e66696d12472ba24e85de1Test
https://pubmed.ncbi.nlm.nih.gov/32528832Test