المؤلفون: Maatoug, Sonia, Cheikh, Amani, Khamessi, Oussema, Tabka, Hager, Landoulsi, Zied, Guigonis, Jean-Marie, Diochot, Sylvie, Bendahhou, Saïd, Benkhalifa, Rym

المساهمون: Biomolécules, Venins et Applications Théranostiques Tunis, Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Tunis El Manar (UTM), Laboratoire des Venins et Biomolécules Thérapeutiques - Laboratory of Venoms and Therapeutic Biomolecules (LR11IPT08), Université de Carthage (Tunisie) (UCAR), Transporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux (TIRO-MATOs UMR E4320), Service Hospitalier Frédéric Joliot (SHFJ), Université Paris-Saclay-Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Institut des Sciences du Vivant Frédéric JOLIOT (JOLIOT), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Université Côte d'Azur (UniCA), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA), Laboratoire de PhysioMédecine Moléculaire (LP2M), This research was funded by the Tunisian Ministry of Higher Education and Scientific Research: LR11IPT08, and AFM #19928 (to SB).

المصدر: ISSN: 1661-6596.

مصطلحات موضوعية: Kv3.1 channel, Androctonus australis hector venom, open channel blocker, alpha-KTx, MESH: Animals, MESH: Humans, MESH: Molecular Docking Simulation, MESH: Potassium Channel Blockers, MESH: Scorpion Venoms, MESH: Scorpions, MESH: Shaw Potassium Channels, MESH: Xenopus laevis, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34830172; hal-03455259; https://hal.science/hal-03455259Test; https://hal.science/hal-03455259/documentTest; https://hal.science/hal-03455259/file/ijms2021.pdfTest; PUBMED: 34830172; PUBMEDCENTRAL: PMC8618407

الإتاحة: https://doi.org/10.3390/ijms222212290Test
https://hal.science/hal-03455259Test
https://hal.science/hal-03455259/documentTest
https://hal.science/hal-03455259/file/ijms2021.pdfTest

المؤلفون: Sonia Maatoug, Amani Cheikh, Oussema Khamessi, Hager Tabka, Zied Landoulsi, Jean-Marie Guigonis, Sylvie Diochot, Saïd Bendahhou, Rym Benkhalifa

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 22; Pages: 12290

مصطلحات موضوعية: Kv3.1 channel, Androctonus australis hector venom, open channel blocker, alpha-KTx

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Toxicology; https://dx.doi.org/10.3390/ijms222212290Test

الإتاحة: https://doi.org/10.3390/ijms222212290Test

المؤلفون: Lipton, S. A., Posina, Venkata Rayudu, Chen, H.-S. V.

مصطلحات موضوعية: Glutamate, Neurological disorders, Excitatory postsynaptic current, Open-channel blocker

العلاقة: https://zenodo.org/communities/cognition-mathTest; https://dx.doi.org/10.5281/zenodo.3924730Test

الإتاحة: https://doi.org/10.5281/zenodo.392473110.5281/zenodo.3924730Test
https://zenodo.org/record/3924731Test

المؤلفون: Rym Benkhalifa, Hager Tabka, Saïd Bendahhou, Sonia Maatoug, Jean-Marie Guigonis, Sylvie Diochot, Zied Landoulsi, Amani Cheikh, Oussema Khamessi

المساهمون: Biomolécules, Venins et Applications Théranostiques [Tunis], Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Tunis El Manar (UTM), Laboratoire des Venins et Biomolécules Thérapeutiques - Laboratory of Venoms and Therapeutic Biomolecules (LR11IPT08), Université de Carthage - University of Carthage, Transporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux (TIRO-MATOs - UMR E4320), Service Hospitalier Frédéric Joliot (SHFJ), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-UMR E4320 (TIRO-MATOs), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Côte d'Azur (UCA), Institut de pharmacologie moléculaire et cellulaire (IPMC), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Laboratoire de PhysioMédecine Moléculaire (LP2M), This research was funded by the Tunisian Ministry of Higher Education and Scientific Research: LR11IPT08, and AFM #19928 (to SB)., UMR E4320 (TIRO-MATOs), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Côte d'Azur (UCA)-Service Hospitalier Frédéric Joliot (SHFJ), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, Vol 22, Iss 12290, p 12290 (2021)
International Journal of Molecular Sciences, 2021, 22 (22), pp.12290. ⟨10.3390/ijms222212290⟩
International Journal of Molecular Sciences, MDPI, 2021, 22 (22), pp.12290. ⟨10.3390/ijms222212290⟩

مصطلحات موضوعية: QH301-705.5, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, In silico, Androctonus australis, Lysine, MESH: Shaw Potassium Channels, Venom, Peptide, Kv3.1 channel, Catalysis, Inorganic Chemistry, 03 medical and health sciences, chemistry.chemical_compound, MESH: Scorpion Venoms, 0302 clinical medicine, MESH: Xenopus laevis, open channel blocker, MESH: Potassium Channel Blockers, MESH: Molecular Docking Simulation, MESH: Animals, Biology (General), Physical and Theoretical Chemistry, Lipid bilayer, QD1-999, Molecular Biology, Spectroscopy, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, MESH: Humans, Natural product, biology, Organic Chemistry, alpha-KTx, General Medicine, biology.organism_classification, MESH: Scorpions, Computer Science Applications, Chemistry, Androctonus australis hector venom, Biochemistry, chemistry, Docking (molecular), [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2bcdf793a39b014236fa9e969861beTest
https://doi.org/10.3390/ijms222212290Test

المؤلفون: Barbosa, Cindy, Tan, Zhi-Yong, Wang, Ruizhong, Xie, Wenrui, Strong, Judith, Patel, Reesha, Vasko, Michael, Zhang, Jun-Ming, Cummins, Theodore

مصطلحات موضوعية: Sodium channels, Resurgent currents, SCN8A, SCN4B, SCN2B, Navβ4, Nav1.6, Open-channel blocker, Sensory neurons, DRG neurons, Beta subunits, Navβ2

العلاقة: http://www.molecularpain.com/content/11/1/60Test

الإتاحة: http://www.molecularpain.com/content/11/1/60Test

المؤلفون: Limapichat, Walrati, Yu, Wesley Y., Branigan, Emma, Lester, Henry A., Dougherty, Dennis A.

المصدر: ACS Chemical Neuroscience, 4(2), 255-260, (2013-02)

مصطلحات موضوعية: Memantine, open-channel blocker, amantadine, unnatural amino acid mutagenesis

العلاقة: https://doi.org/10.1021/cn300180aTest; oai:authors.library.caltech.edu:1kkdy-zxe50; https://www.ncbi.nlm.nih.gov/pmc/PMC3751542Test; eprintid:37670; resolverid:CaltechAUTHORS:20130328-101734866

الإتاحة: https://doi.org/10.1021/cn300180aTest
https://www.ncbi.nlm.nih.gov/pmc/PMC3751542Test

المؤلفون: Lipton, S. A., Posina, Venkata Rayudu, Chen, H.-S. V.

مصطلحات موضوعية: Glutamate, Neurological disorders, Excitatory postsynaptic current, Open-channel blocker, Ideal Antagonist, Prophylactic, NMDA, Clinical Tolerance, Side effects, Pharmaceutical drugs, Brain, Molecular neuroscience, Neuroscience, Neurology, Clinical neurology, Neurological Diseases, Pathology, Physiology, FOS Biological sciences, Neuroprotection, Excitotoxicity, MK-801, Memantine, Neuronal Death, Optimization, Kinetic theory, Rate constants, Binding, Unbinding, Ionic Pore

العلاقة: https://dx.doi.org/10.5281/zenodo.11106832Test; https://dx.doi.org/10.5281/zenodo.3924731Test

الإتاحة: https://doi.org/10.5281/zenodo.392473010.5281/zenodo.1110683210.5281/zenodo.3924731Test

المؤلفون: Shigetoshi Oiki, 老木 成稔

المصدر: 膜 / MEMBRANE. 1997, 22(6):307

المؤلفون: Wenrui Xie, Michael R. Vasko, Zhi‑Yong Tan, Ruizhong Wang, Cindy Barbosa, Reesha R. Patel, Judith A. Strong, Jun-Ming Zhang, Theodore R. Cummins

المصدر: Molecular Pain

مصطلحات موضوعية: Dorsum, Male, SCN8A, Sensory neurons, Sensory Receptor Cells, Central nervous system, Molecular Sequence Data, Sodium channels, Beta subunits, Sensory system, Models, Biological, Rats sprague dawley, Sodium current, Rats, Sprague-Dawley, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Ganglia, Spinal, medicine, Voltage-Gated Sodium Channel beta-2 Subunit, Animals, Humans, DRG neurons, Amino Acid Sequence, Resurgent currents, 030304 developmental biology, 0303 health sciences, Nav1.6, Voltage-Gated Sodium Channel beta-4 Subunit, Chemistry, Sodium channel, Research, Anesthesiology and Pain Medicine, medicine.anatomical_structure, Open-channel blocker, nervous system, NAV1.6 Voltage-Gated Sodium Channel, Gene Knockdown Techniques, Molecular Medicine, SCN2B, Navβ4, SCN4B, Neuroscience, Ion Channel Gating, Navβ2, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511511cf635e596c98e27f81d4a47c63Test
https://pubmed.ncbi.nlm.nih.gov/26408173Test

المؤلفون: Shigetoshi Oiki, Tomoko Tominaga, Ravshan Z. Sabirov, Yasunobu Okada, Akiko Miwa

المصدر: The Journal of General Physiology

مصطلحات موضوعية: Potassium Channels, Arginine, Physiology, Protein subunit, Xenopus, Mutant, Molecular Sequence Data, Cesium, Gene Expression, Sensitivity and Specificity, Article, open channel blocker, Cations, Animals, Magnesium, Binding site, Potassium Channels, Inwardly Rectifying, Mg2+ block, Cells, Cultured, Sequence Homology, Amino Acid, Chemistry, Inward-rectifier potassium ion channel, coexpression, Hydrogen-Ion Concentration, Molecular biology, Potassium channel, electrical distance, Electrophysiology, Barium, Biophysics, Mutagenesis, Site-Directed, Oocytes, Ligand-gated ion channel, Calcium, Steady state (chemistry), Ion Channel Gating, mutagenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40d8e61426864af5e515281c01c5303Test
http://europepmc.org/articles/PMC2229401Test