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1دورية أكاديمية
المصدر: International Journal of Nanomedicine, Vol Volume 19, Pp 4977-4994 (2024)
مصطلحات موضوعية: oligonucleotide drug, functional nanocarriers, hippocampus, sh-sy5y, 3xtg-ad, Medicine (General), R5-920
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Sarah M. Davis, Vignesh N. Hariharan, Agnes Lo, Anton A. Turanov, Dimas Echeverria, Jacquelyn Sousa, Nicholas McHugh, Annabelle Biscans, Julia F. Alterman, S. Ananth Karumanchi, Melissa J. Moore, Anastasia Khvorova
المصدر: Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 135-149 (2022)
مصطلحات موضوعية: siRNA therapeutics, oligonucleotides, preeclampsia, oligonucleotide drug design, extrahepatic delivery, angiogenic disorders, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S2162253122001615Test; https://doaj.org/toc/2162-2531Test
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3دورية أكاديمية
المؤلفون: Davis, Sarah M, Hariharan, Vignesh N, Lo, Agnes, Turanov, Anton A, Echeverria, Dimas, Sousa, Jacquelyn, McHugh, Nicholas, Biscans, Annabelle, Alterman, Julia F, Karumanchi, S Ananth, Moore, Melissa J, Khvorova, Anastasia
المساهمون: Program in Molecular Medicine, RNA Therapeutics Institute
المصدر: Molecular therapy. Nucleic acids ; 29 ; 135 ; 149 ; United States
مصطلحات موضوعية: angiogenic disorders, extrahepatic delivery, methyl rich siRNA, oligonucleotide drug design, oligonucleotides, pre-clinical development, preeclampsia, siRNA optimization, siRNA therapeutics
العلاقة: Molecular Therapy Nucleic Acids; https://doi.org/10.1016/j.omtn.2022.06.009Test; Davis SM, Hariharan VN, Lo A, Turanov AA, Echeverria D, Sousa J, McHugh N, Biscans A, Alterman JF, Karumanchi SA, Moore MJ, Khvorova A. Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1. Mol Ther Nucleic Acids. 2022 Jun 22;29:135-149. doi:10.1016/j.omtn.2022.06.009. PMID: 35847173; PMCID: PMC9263991.; http://hdl.handle.net/20.500.14038/52702Test; Molecular therapy. Nucleic acids
الإتاحة: https://doi.org/10.1016/j.omtn.2022.06.009Test
https://doi.org/20.500.14038/52702Test
https://hdl.handle.net/20.500.14038/52702Test -
4دورية أكاديمية
المؤلفون: Tang, Kegong, Wang, Xiaona, Jiang, Zhenyu, Chen, Mingrui, Deng, Xingyu, Mei, Song, Ma, Yiming, Du, Xinyi, Guo, Shaoting, Lin, Yexuan, Dong, Yixin, Liu, Dengyuan, Xu, Longxin, Jiang, Chengyu
المصدر: IUBMB Life ; ISSN:1521-6551
مصطلحات موضوعية: hyperglycemia, oligonucleotide drug, oral administration
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5دورية أكاديمية
المؤلفون: Haihong Bai, Yuanguo Cheng, Jinjing Che
المصدر: Frontiers in Pharmacology, Vol 12 (2021)
مصطلحات موضوعية: hepatocellular carcinoma, antisense oligonucleotide drug, nanoliposome, pharmacokinetics, PBPK model, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2021.769538/fullTest; https://doaj.org/toc/1663-9812Test
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6رسالة جامعية
المؤلفون: Garwood, Jake
مصطلحات موضوعية: Breast cancer, Triple-negative breast cancer, DNA damage response, Breast cancer susceptibility gene, Double-strand breaks, Homologous recombination, Oligonucleotide drug, RNA therapeutics, Synthetic lethality, Chemotherapy resistance
وصف الملف: application/pdf
العلاقة: https://eprints.qut.edu.au/244746/2/Jake%2BGarwood%2BThesis%2B%283%29.pdfTest; Garwood, Jake (2023) Assessing the efficacy of a new oligonucleotide drug in triple negative breast cancer. Master of Philosophy thesis, Queensland University of Technology.; https://eprints.qut.edu.au/244746Test/; Faculty of Health; School of Biomedical Sciences
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7
المؤلفون: Tavara, Shirin, 1982, Schliep, Alexander, 1967, Basu, Debabrota
المصدر: 21st European Conference on Machine Learning and Principles and Practice of Knowledge Discovery in Databases, ECML PKDD 2021, Virtual, Online Communications in Computer and Information Science. 1525 CCIS:459-467
مصطلحات موضوعية: Federated learning, Oligonucleotide drug molecules, SVM, ADMM, Differential privacy, Distributed learning
الوصول الحر: https://research.chalmers.se/publication/529135Test
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8صورة
مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, hepatocellular carcinoma, antisense oligonucleotide drug, nanoliposome, pharmacokinetics, PBPK model
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9صورة
المؤلفون: Haihong Bai, Yuanguo Cheng, Jinjing Che
مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, hepatocellular carcinoma, antisense oligonucleotide drug, nanoliposome, pharmacokinetics, PBPK model
الإتاحة: https://doi.org/10.3389/fphar.2021.769538.s001Test
https://figshare.com/articles/figure/Image1_Pharmacokinetics_and_Disposition_of_Heparin-Binding_Growth_Factor_Midkine_Antisense_Oligonucleotide_Nanoliposomes_in_Experimental_Animal_Species_and_Prediction_of_Human_Pharmacokinetics_Using_a_Physiologically_Based_Pharmacokinetic_M/16921231Test -
10
المؤلفون: Zihua Gong, Shuang Liu, Sarah Ondrejka, Wei Chen, Qing Yi, Yi Hu, Hua Fang, Jianjun Zhao, Jaroslaw P. Maciejewski, Chen Li, Jianhong Lin, Jing Fang, Frederic J Reu
المصدر: Leukemia
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, DNA Repair, DNA damage, DNA repair, Poly (ADP-Ribose) Polymerase-1, Apoptosis, Mice, SCID, Monoclonal Gammopathy of Undetermined Significance, Article, Cell Line, DNA Ligase ATP, Mice, 03 medical and health sciences, A-NHEJ, medicine, Animals, Humans, Poly-ADP-Ribose Binding Proteins, MALAT1, RNase H, Cell Death, long non-coding RNA, biology, Oligonucleotide, Chemistry, RNA, Hematology, DNA Repair Pathway, medicine.disease, 3. Good health, Gene Expression Regulation, Neoplastic, multiple myeloma, HEK293 Cells, 030104 developmental biology, Oncology, Cancer research, Proteasome inhibitor, biology.protein, RNA Interference, RNA, Long Noncoding, antisense oligonucleotide drug, Monoclonal gammopathy of undetermined significance, DNA Damage, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61f00b32d764402cc292688b8f22e87Test
https://doi.org/10.1038/s41375-018-0104-2Test