المؤلفون: Ping Dong, Weibo Dai, Mengyue Su, Shukun Wang, Yuexiang Ma, Tingting Zhao, Feng Zheng, Peng Sun

المصدر: Frontiers in Endocrinology, Vol 14 (2024)

مصطلحات موضوعية: premenstrual syndrome, orexin, symptoms, mechanism, new target, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fendo.2023.1266806/fullTest; https://doaj.org/toc/1664-2392Test

الوصول الحر: https://doaj.org/article/e1eec280652d407fae628f06cf1ac6f5Test

المؤلفون: Rachel Sim, Chuan Yang, Yi Yan Yang

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Immunology, Developmental Biology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, reduce cell proliferation, macromolecular chemotherapeutic development, derived growth factor, also identify similarities, akt pathway leading, exact molecular targets, potential new target, phosphatidylinositol 3kinase inhibitors, based protein profiling, main protein target, protein targets, morphological profiling, mydgf protein, report myeloid, repeated use

العلاقة: https://figshare.com/articles/journal_contribution/Chemical_Proteomics_and_Morphological_Profiling_Revealing_MYDGF_as_a_Target_for_Synthetic_Anticancer_Macromolecules/25002080Test

الإتاحة: https://doi.org/10.1021/acs.biomac.3c01101.s001Test
https://figshare.com/articles/journal_contribution/Chemical_Proteomics_and_Morphological_Profiling_Revealing_MYDGF_as_a_Target_for_Synthetic_Anticancer_Macromolecules/25002080Test

المؤلفون: JIN Can, DENG Ying, CAO Nan, ZHANG Xiaoli, XIAO Changyi, HE Jiangang, HE Gongwei, LI Shigang

المصدر: Shipin Kexue, Vol 44, Iss 7, Pp 295-302 (2023)

مصطلحات موضوعية: tea polyphenols, high-fat diet, non-alcoholic fatty liver disease, preventive effect, new target, Food processing and manufacture, TP368-456

وصف الملف: electronic resource

العلاقة: https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-7-034.pdfTest; https://doaj.org/toc/1002-6630Test

الوصول الحر: https://doaj.org/article/ec716243199d408899f6368a1f5d9dbeTest

المؤلفون: Xuehan Li, Wenlong Kuang, Zhihua Qiu, Zihua Zhou

المصدر: Frontiers in Endocrinology, Vol 14 (2023)

مصطلحات موضوعية: GPER, aldosterone, nongenomic pathways, hypertension, new target, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fendo.2023.1226458/fullTest; https://doaj.org/toc/1664-2392Test

الوصول الحر: https://doaj.org/article/0cb291be23ad4af09ae903056f8432a8Test

المؤلفون: Pengxiang ZHANG, Lin ZENG, Lu MENG, Qian HUANG, Gaoxiang WANG, Deliang LIU

المصدر: Zhongguo quanke yixue, Vol 25, Iss 20, Pp 2551-2557 (2022)

مصطلحات موضوعية: diabetes mellitus, type 2, new target drugs, drug therapy, review, Medicine

وصف الملف: electronic resource

العلاقة: https://www.chinagp.net/fileup/1007-9572/PDF/zx20220115.pdfTest; https://doaj.org/toc/1007-9572Test

الوصول الحر: https://doaj.org/article/5a35f80f36a349c7bdda4c77801ac94dTest

المؤلفون: Rossella Cannarella, Davor Jezek, Rosita A. Condorelli, Aldo E. Calogero

المصدر: Frontiers in Endocrinology, Vol 14 (2023)

مصطلحات موضوعية: infertility, azoospermia, oligozoospermia, idiopathic infertility, new target, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fendo.2023.1172878/fullTest; https://doaj.org/toc/1664-2392Test

الوصول الحر: https://doaj.org/article/13b0874fc5db4d3ab5d43bef7439a197Test

المؤلفون: Rahimova, Rahila, Nogaret, Pauline, Huteau, Valérie, Gelin, Muriel, Clément, David, A., Labesse, Gilles, Pochet, Sylvie, Blanc-Potard, Anne‐béatrice, Lionne, Corinne

المساهمون: Centre de Biologie Structurale Montpellier (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Laboratory of Pathogen and Host Immunity Montpellier (LPHI), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Chimie biologique épigénétique - Epigenetic Chemical Biology (EpiCBio), Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), This work was funded by the Agence Nationale de la Recherche (ANR-17-CE18-0011-02) and supportedby Institut Pasteur, the Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé etde la Recherche Médicale (INSERM) and University of Montpellier. R.R., P.N. and D.A.C. acknowledgeANR for financial support. The authors would like to thank the Chemogenomic and Biological ScreeningPlatform (Institut Pasteur, France) for carrying out the cytotoxicity experiments and Frédéric Bonhomme(CNRS, UMR3523, Paris) for assisting with HRMS analysis. We thank Dr. Catherine Dunyach-Remy andAndréa Clary (INSERM U1047) for helpful discussion. We also acknowledge support from the FrenchInfrastructure for Integrated Structural Biology (FRISBI) ANR-10-INSB-05-01., ANR-17-CE18-0011,NADKiller,NADK : une nouvelle cible bactérienne pour le développement d'antibiotiques(2017), ANR-10-INBS-0005,FRISBI,Infrastructure Française pour la Biologie Structurale Intégrée(2010)

المصدر: ISSN: 1742-464X.

مصطلحات موضوعية: steady state rate constant, NADK 1 from Listeria monocytogenes, NAD +, nicotinamide adenine dinucleotide, NADK, NAD kinase, NADP +, nicotinamide adenine dinucleotide phosphate, NADK from Pseudomonas aeruginosa, NADK from Staphylococcus aureus, SEC, benzamide adenine dinucleoside analogue, new target enzyme, zebrafish, antibiotics, ESKAPE, Crystal structure, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36036789; hal-03765406; https://hal.science/hal-03765406Test; https://hal.science/hal-03765406/documentTest; https://hal.science/hal-03765406/file/Accepted%20manuscript.pdfTest; PUBMED: 36036789

الإتاحة: https://doi.org/10.1111/febs.16604Test
https://hal.science/hal-03765406Test
https://hal.science/hal-03765406/documentTest
https://hal.science/hal-03765406/file/Accepted%20manuscript.pdfTest

المؤلفون: Haifeng Ye, Yuval Rinkevich

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 3; Pages: 2936

مصطلحات موضوعية: fascia layer, biomaterials, new target, wound healing

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Biology; https://dx.doi.org/10.3390/ijms24032936Test

الإتاحة: https://doi.org/10.3390/ijms24032936Test

المؤلفون: Katarzyna Stachowicz, Magdalena Sowa-Kućma

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: depression, antidepressants, new target, glutamate receptors, DSCAM, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2022.988648/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/bc4272596308445a91324d7efd8e91f7Test

المؤلفون: Mengxu Li, Jinlai Zhang, Qiuyan Bai, Lixia Fang, Hao Song, Yingxiu Cao

المصدر: Frontiers in Microbiology, Vol 13 (2022)

مصطلحات موضوعية: new target identification, non-homologous end joining-mediated integration, Yarrowia lipolytica, fatty alcohols, RNA-Seq, Microbiology, QR1-502

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fmicb.2022.898884/fullTest; https://doaj.org/toc/1664-302XTest

الوصول الحر: https://doaj.org/article/670abba319e34ea09437b0ee619127cfTest