التفاصيل البيبلوغرافية
| العنوان: |
Detection of Bromochloro Alkanes in Indoor Dust Using a Novel CP-Seeker Data Integration Tool |
| المؤلفون: |
Thomas J. McGrath, Julien Saint-Vanne, Sébastien Hutinet, Walter Vetter, Giulia Poma, Yukiko Fujii, Robin E. Dodson, Boris Johnson-Restrepo, Dudsadee Muenhor, Bruno Le Bizec, Gaud Dervilly, Adrian Covaci, Ronan Cariou |
| سنة النشر: |
2024 |
| المجموعة: |
Smithsonian Institution: Figshare |
| مصطلحات موضوعية: |
Ecology, Science Policy, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, neutral silica cartridges, carbon chain lengths, acidified silica cleanup, 31 , 30 , 24 , 2 , 18 , 14 , variation ≤ 10, levels may approach, including australia (<, pcas ), subclasses, indoor dust using, dust samples indicated, indoor dust, n <, 10 ), may migrate, america (<, 9 ), united states, seven samples |
| الوصف: |
Bromochloro alkanes (BCAs) have been manufactured for use as flame retardants for decades, and preliminary environmental risk screening suggests they are likely to behave similarly to polychlorinated alkanes (PCAs), subclasses of which are restricted as Stockholm Convention Persistent Organic Pollutants (POPs). BCAs have rarely been studied in the environment, although some evidence suggests they may migrate from treated-consumer materials into indoor dust, resulting in human exposure via inadvertent ingestion. In this study, BCA-C 14 mixture standards were synthesized and used to validate an analytical method. This method relies on chloride-enhanced liquid chromatography–electrospray ionization–Orbitrap-high resolution mass spectrometry (LC-ESI-Orbitrap-HRMS) and a novel CP-Seeker integration software package for homologue detection and integration. Dust sample preparation via ultrasonic extraction, acidified silica cleanup, and fractionation on neutral silica cartridges was found to be suitable for BCAs, with absolute recovery of individual homologues averaging 66 to 78% and coefficients of variation ≤10% in replicated spiking experiments ( n = 3). In addition, a total of 59 indoor dust samples from six countries, including Australia ( n = 10), Belgium ( n = 10), Colombia ( n = 10), Japan ( n = 10), Thailand ( n = 10), and the United States of America ( n = 9), were analyzed for BCAs. BCAs were detected in seven samples from the U.S.A., with carbon chain lengths of C 8 , C 10 , C 12 , C 14 , C 16 , C 18 , C 24 to C 28 , C 30 and C 31 observed overall, though not detected in samples from any other countries. Bromine numbers of detected homologues in the indoor dust samples ranged Br 1–4 as well as Br 7 , while chlorine numbers ranged Cl 2–11 . BCA-C 18 was the most frequently detected, observed in each of the U.S.A. samples, while the most prevalent degrees of halogenation were homologues of Br 2 and Cl 4–5 . Broad estimations of BCA concentrations in the dust samples indicated that levels may approach those of ... |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| العلاقة: |
https://figshare.com/articles/journal_contribution/Detection_of_Bromochloro_Alkanes_in_Indoor_Dust_Using_a_Novel_CP-Seeker_Data_Integration_Tool/25404034Test |
| DOI: |
10.1021/acs.analchem.3c05800.s001 |
| الإتاحة: |
https://doi.org/10.1021/acs.analchem.3c05800.s001Test |
| حقوق: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.62FEFCE4 |
| قاعدة البيانات: |
BASE |
