المؤلفون: Lee‐Moay Lim, Yi‐Chen Lee, Ting‐Wei Lin, Zi‐Xuan Hong, Wei‐Chi Hsu, Hung‐Lung Ke, Daw‐Yang Hwang, Wen‐Yu Chung, Wei‐Ming Li, Hui‐Hui Lin, Hung‐Tien Kuo, A‐Mei Huang

المصدر: Kaohsiung Journal of Medical Sciences, Vol 40, Iss 5, Pp 445-455 (2024)

مصطلحات موضوعية: AKT‐mTOR pathway, neurotrophic receptor tyrosine kinase 3 (NTRK3), prognosis, tropomyosin‐related kinase (TrK), upper tract urothelial carcinoma (UTUC), Medicine (General), R5-920

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1607-551XTest; https://doaj.org/toc/2410-8650Test

الوصول الحر: https://doaj.org/article/9e5d7c95c6ce4eaba4f6fa0ce58da1f1Test

المؤلفون: Suzuki, Chiaki, 鈴木, 千晶, スズキ, チアキ

مصطلحات موضوعية: acquired resistance, neurotrophic receptor tyrosine kinase (NTRK) gene fusion, NTRK1-G595R, repotrectinib, tropomyosin-related kinase inhibitors

وصف الملف: application/pdf; text/html

الوصول الحر: https://ndlsearch.ndl.go.jp/books/R100000039-I12969707Test

Degree: 博士(医学) -- Doctor of Medical Science -- 京都大学

المؤلفون: DuBois, Steven G, Laetsch, Theodore W, Federman, Noah, Turpin, Brian K, Albert, Catherine M, Nagasubramanian, Ramamoorthy, Anderson, Megan E, Davis, Jessica L, Qamoos, Hope E, Reynolds, Mark E, Cruickshank, Scott, Cox, Michael C, Hawkins, Douglas S, Mascarenhas, Leo, Pappo, Alberto S

المصدر: Cancer. 124(21)

مصطلحات موضوعية: Pediatric, Rare Diseases, Cancer, Patient Safety, Clinical Research, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Child, Child, Preschool, Disease Progression, Female, Fibrosarcoma, Humans, Infant, Infant, Newborn, Male, Neoadjuvant Therapy, Oncogene Proteins, Fusion, Pyrazoles, Pyrimidines, Receptor, trkA, Sarcoma, Soft Tissue Neoplasms, Treatment Outcome, infantile fibrosarcoma, larotrectinib, local control, neurotrophic receptor tyrosine kinase, pediatric, sarcoma, surgery, tropomyosin receptor kinase (TRK) fusion., Oncology and Carcinogenesis, Public Health and Health Services, Oncology & Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1jk7s5m0Test

المؤلفون: Vanessa Young, Daniel Wong, Max Yan, Fiona Maclean

المصدر: Human Pathology Reports, Vol 28, Iss , Pp 300618- (2022)

مصطلحات موضوعية: Neurotrophic receptor tyrosine kinase (NTRK), Sarcoma, Pathology, RB1-214

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2772736X22000305Test; https://doaj.org/toc/2772-736XTest

الوصول الحر: https://doaj.org/article/01132bf9b9c641979a66504a35cd3d50Test

المؤلفون: Tingting Jiang, Guan Wang, Yao Liu, Lu Feng, Meng Wang, Jie Liu, Yi Chen, Liang Ouyang

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 355-372 (2021)

مصطلحات موضوعية: Tropomyosin receptor kinase, Neurotrophic receptor tyrosine kinase fusions, Small-molecule inhibitor, NTRK fusion cancer, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2211383520305864Test; https://doaj.org/toc/2211-3835Test

الوصول الحر: https://doaj.org/article/d6024459ff714d0d9e1741d893cc1526Test

المؤلفون: Lim, Lee-Moay, Lee, Yi-Chen, Lin, Ting-Wei, Hong, Zi-Xuan, Hsu, Wei-Chi, Ke, Hung-Lung, Hwang, Daw-Yang, Chung, Wen-Yu, Li, Wei-Ming, Lin, Hui-Hui, Kuo, Hung-Tien, Huang, A-Mei

المصدر: Kaohsiung J Med Sci ; ISSN:2410-8650 ; Volume:40 ; Issue:5

مصطلحات موضوعية: AKT‐mTOR pathway, neurotrophic receptor tyrosine kinase 3 (NTRK3), prognosis, tropomyosin‐related kinase (TrK), upper tract urothelial carcinoma (UTUC)

العلاقة: https://doi.org/10.1002/kjm2.12824Test; https://pubmed.ncbi.nlm.nih.gov/38593276Test

الإتاحة: https://doi.org/10.1002/kjm2.12824Test
https://pubmed.ncbi.nlm.nih.gov/38593276Test

المؤلفون: Zongliang Liu (1920442), Pengfei Yu (680800), Lin Dong (1458793), Wenyan Wang (171659), Sijin Duan (11123724), Bingsi Wang (11123727), Xiaoyan Gong (299388), Liang Ye (6646), Hongbo Wang (587749), Jingwei Tian (587745)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Hematology, Infectious Diseases, Plant Biology, Virology, Chemical Sciences not elsewhere classified, Compound 10, WT, RXDX, exhibit effectiveness, larotrectinib sulfate, TPX, next-generation Trk inhibitors, TRK inhibitors, proteins TrkA, NMS-E, Next-Generation Pan-TRK Kinase Inhi., MT, vivo studies, NTRK 3 encode, neurotrophic receptor tyrosine kinase, larotrectinib treatment failure, optimization

العلاقة: https://figshare.com/articles/journal_contribution/Discovery_of_the_Next-Generation_Pan-TRK_Kinase_Inhibitors_for_the_Treatment_of_Cancer/14971989Test

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c00712.s003Test

المؤلفون: Solin Ali, Karin Toews, Silke Schwiebert, Anika Klaus, Annika Winkler, Laura Grunewald, Lena Oevermann, Hedwig E. Deubzer, Alicia Tüns, Michael C. Jensen, Anton G. Henssen, Angelika Eggert, Johannes H. Schulte, Esther Schwich, Vera Rebmann, Alexander Schramm, Annette Künkele

المصدر: Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: immunotherapy, pediatric oncology, neuroblastoma, solid tumors, neurotrophic receptor tyrosine kinase, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fimmu.2020.00531/fullTest; https://doaj.org/toc/1664-3224Test

الوصول الحر: https://doaj.org/article/08d9b061f34547348113e50ddc8b2d15Test

المؤلفون: Fred, Senem Merve, Laukkanen, Liina, Brunello, Cecilia A., Vesa, Liisa, Göös, Helka, Cardon, Iseline, Moliner, Rafael, Maritzen, Tanja, Varjosalo, Markku, Casarotto, Plinio C., Castren, Eero

المساهمون: Neuroscience Center, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Institute of Biotechnology, University Management, Molecular Systems Biology

مصطلحات موضوعية: brain-derived neurotrophic factor (BDNF), clathrin, drug action, receptor tyrosine kinase, molecular pharmacology, neurotrophic receptor tyrosine kinase 2 (NTRK2), adaptor protein complex-2 (AP-2), neuroplasticity, NERVE GROWTH-FACTOR, NEUROTROPHIC FACTOR, RETROGRADE TRANSPORT, SURFACE EXPRESSION, SIGNALING PATHWAYS, PROTEOMIC ANALYSIS, PLASMA-MEMBRANE, AMPA RECEPTORS, TRAFFICKING, 1182 Biochemistry, cell and molecular biology, 3112 Neurosciences

وصف الملف: application/pdf

العلاقة: This work was supported by European Research Council (ERC) Grant 322742 (iPLASTICITY), EU Joint Programme-Neurodegenerative Disease Research (JPND) project CircProt Grants 1301225 and 643417, Academy of Finland Grants 294710 and 307416, the Sigrid Juselius Foundation, the Jane and Eljas Erkko Foundation, and Deutsche Forschungsgemeinschaft (DFG) Grant SFB958/A01. The authors declare that they have no conflicts of interest with the contents of this article.; Fred , S M , Laukkanen , L , Brunello , C A , Vesa , L , Göös , H , Cardon , I , Moliner , R , Maritzen , T , Varjosalo , M , Casarotto , P C & Castren , E 2019 , ' Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2 ' , Journal of Biological Chemistry , vol. 294 , no. 48 , pp. 18150-18161 . https://doi.org/10.1074/jbc.RA119.008837Test; ORCID: /0000-0002-1402-2791/work/68612764; ORCID: /0000-0002-1340-9732/work/68615478; ORCID: /0000-0002-6175-4872/work/68615980; ORCID: /0000-0002-1090-4631/work/68616202; ORCID: /0000-0003-1992-5014/work/68617924; 20c8eb1e-d690-4fd5-a9e6-cad56c04870d; http://hdl.handle.net/10138/313776Test; 000505547900013

الإتاحة: http://hdl.handle.net/10138/313776Test

المؤلفون: Ali, Solin, Toews, Karin, Schwiebert, Silke, Klaus, Anika, Winkler, Annika, Grunewald, Laura, Oevermann, Lena, Deubzer, Hedwig E., Tüns, Alicia, Jensen, Michael C., Henssen, Anton George, Eggert, Angelika, Schulte, Johannes Hubertus, Schwich, Esther, Rebmann, Vera, Schramm, Alexander, Künkele, Annette

مصطلحات موضوعية: immunotherapy, pediatric oncology, neuroblastoma, solid tumors, neurotrophic receptor tyrosine kinase, ddc:610

وصف الملف: application/pdf

العلاقة: https://refubium.fu-berlin.de/handle/fub188/27398Test; http://dx.doi.org/10.17169/refubium-27154Test

الإتاحة: https://doi.org/10.17169/refubium-27154Test
https://doi.org/10.3389/fimmu.2020.00531Test
https://refubium.fu-berlin.de/handle/fub188/27398Test