المؤلفون: Voskressensky L.G., Vorobiev I.V., Borisova T.N., Varlamov A.V.

المصدر: Journal of Organic Chemistry

مصطلحات موضوعية: Acetylene, Ammonium compounds, Chemical activation, Chemical reactions, Chemical reactivity, Hydrocarbons, Microfluidics, Activated alkynes, American Chemical Society (ACS), Ammonium ylides, Chemical equations, Multistage process (MSP), Naphthyridine, Reactivity (Chemical), Synthesis (of chiral ionic liquids), Synthesis (chemical), alkyne derivative, ammonium derivative, benzo[b]pyrrolo[2,1 f][1.6]naphthyridine derivative, naphthyridine derivative, pyrrole derivative, article, carbon nuclear magnetic resonance, crystal structure, molecular stability, proton nuclear magnetic resonance, quantum yield, reaction analysis, synthesis, X ray diffraction

العلاقة: https://doi.org/10.1021/jo8003698Test; https://openrepository.ru/article?id=253519Test

الإتاحة: https://doi.org/10.1021/jo8003698Test
https://openrepository.ru/article?id=253519Test

المؤلفون: Voskressensky L.G., Borisova T.N., Listratova A., Vorobiev I.V., Aleksandrov G.G., Varlamov A.V.

المصدر: Journal of Heterocyclic Chemistry

مصطلحات موضوعية: 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de][1,6]naphthyridine, 2,3,3a,4,5,6 hexahydrobenzo[b]pyrido[3,4,5 de] 1,6 naphthyridine, 4 methyl 3 (2 oxopropyl) 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 1 one, ethyl 2 [4 isopropyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de][1,6]naphthyridin 3 yl]acetate, ethyl [10 bromo 4 isopropyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 3 yl]acetate, ethyl [4 methyl 1 oxo 2,3,3a,4,5,6 hexahydro 1h benzo[b]pyrido[3,4,5 de] 1,6 naphthyridin 3 yl]acetate, heterocyclic compound, naphthyridine derivative, unclassified drug, article, carbon nuclear magnetic resonance, chemical structure, crystal structure, electrospray mass spectrometry, proton nuclear magnetic resonance, synthesis

العلاقة: https://doi.org/10.1002/jhet.5570420627Test; https://openrepository.ru/article?id=254009Test

الإتاحة: https://doi.org/10.1002/jhet.5570420627Test
https://openrepository.ru/article?id=254009Test

المؤلفون: Alvur O., Tokgun O., Baygu Y., Kabay N., Gok Y., Akca H.

مصطلحات موضوعية: Ambra1, Apoptosis, Autophagy, Electron microscopy, LC3B, NSCLC, 2,3 bis[1 [2,2,7,7 tetramethyl tetrahydro bis[1,3]dioxolo[4,5 b,4',5' d]pyran 5 methyl] 1h [1,2,3]triazol 4 ylmethylsulfanyl]but 2 enedinitrile, galactose, triazole derivative, unclassified drug, 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one, AMBRA1 protein, human, antineoplastic agent, apoptosis regulatory protein, chloroquine, MAP1LC3B protein, microtubule associated protein, naphthyridine derivative, signal transducing adaptor protein, target of rapamycin kinase, antiproliferative activity, Article, autophagosome, carbon nuclear magnetic resonance, controlled study, HCC78 cell line, human cell, IC50, immunoblotting

العلاقة: Gene; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://doi.org/10.1016/j.gene.2019.06.025Test; https://hdl.handle.net/11499/47436Test; 712; 2-s2.0-85068461283; Q1

الإتاحة: https://doi.org/10.1016/j.gene.2019.06.025Test
https://hdl.handle.net/11499/47436Test

المؤلفون: Qinghong Kong, Jianxin Lv, Shengjiao Yan, Kwen-Jen Chang, Guanlin Wang

المصدر: International Journal of Molecular Sciences; Volume 19; Issue 10; Pages: 2975

مصطلحات موضوعية: naphthyridine derivative, death receptors, apoptosis, caspase-8, necroptosis, melanoma

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Biochemistry; https://dx.doi.org/10.3390/ijms19102975Test

الإتاحة: https://doi.org/10.3390/ijms19102975Test

المؤلفون: Lambrianidou A., Sereti E., Soupsana K., Komini C., Dimas K., Trangas T.

المصدر: Cellular Signalling ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098757316&doi=10.1016%2fj.cellsig.2020.109912&partnerID=40&md5=5a4e8441475a29161b594deedf700570Test

مصطلحات موضوعية: insulin like growth factor 2 messenger RNA binding protein 1, mammalian target of rapamycin complex 2, mammalian target of rapamycin inhibitor, messenger RNA, Myc protein, protein tyrosine kinase, RNA binding protein, saracatinib, serine, torin 1, tyrosine, unclassified drug, 1,3 benzodioxole derivative, 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one, IGF2BP1 protein, human, naphthyridine derivative, quinazoline derivative, small interfering RNA, SRCIN1 protein, vesicular transport adaptor protein, animal experiment, animal model, animal tissue, antineoplastic activity, apoptosis, Article, cell survival, cell viability, controlled study

العلاقة: http://hdl.handle.net/11615/75667Test

الإتاحة: https://doi.org/10.1016/j.cellsig.2020.109912Test
http://hdl.handle.net/11615/75667Test

المؤلفون: Núñez Ventura, Araceli, Sánchez Muñoz, Aránzazu, Burgos García, Carolina, Álvarez-Builla Gómez, Julio

المساهمون: Universidad de Alcalá. Departamento de Química Orgánica

مصطلحات موضوعية: Benzonaphthyridine derivative, Naphthyridine derivative, Pyridine derivative, Pyridinium derivative, Pyridinium n 2' pyridylaminide, Article, Chemical analysis, Chemical modification, Chemical reaction, Chemical structure, Organic chemistry, Priority journal, Synthesis, Ciencia, Química orgánica, Science, Chemistry, organic

وصف الملف: application/pdf

العلاقة: http://dx.doi.org/10.1016/j.tet.2007.04.077Test; info:eu-repo/grantAgreement/CICYT//CTQ2005-08902/ES/N-AMIDAS DE AZINIO ESTABILIZADAS POR HETEROARILO: REACCIONES A TRAVÉS DE ORGANOPALADIOS, SÍNTESIS DE POLIAMINAS DENDRÍMERAS Y REACCIONES RADICALARIAS; Tetrahedron, 2007, v. 63, n. 29, p. 6774-6783; http://hdl.handle.net/10017/3434Test

الإتاحة: https://doi.org/10.1016/j.tet.2007.04.077Test
http://hdl.handle.net/10017/3434Test

المؤلفون: Hakan Akca, Ozge Alvur, Yasemin Baygu, Nilgün Kabay, Yaşar Gök, Onur Tokgun

المساهمون: Uşak Üniversitesi

مصطلحات موضوعية: 0301 basic medicine, Autophagosome, Lung Neoplasms, autophagosome, Apoptosis, IC50, NSCLC, triazole derivative, proton nuclear magnetic resonance, lung tumor, chloroquine, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Gene expression, LC3B, 2,3 bis[1 [2,2,7,7 tetramethyl tetrahydro bis[1,3]dioxolo[4,5 b,4',5' d]pyran 5 methyl] 1h [1,2,3]triazol 4 ylmethylsulfanyl]but 2 enedinitrile, NCI-H1975 cell line, antineoplastic agent, Adaptor Proteins, Signal Transducing/metabolism, Antineoplastic Agents, Apoptosis Regulatory Proteins/metabolism, Autophagy, Carcinoma, Non-Small-Cell Lung/drug therapy/*metabolism, Cell Line, Tumor, Cell Proliferation/drug effects, Cell Survival/drug effects, Chloroquine/chemistry, Drug Resistance, Neoplasm, Drug Screening Assays, Antitumor, Galactose/*chemistry, Humans, Inhibitory Concentration 50, Lung Neoplasms/drug therapy/*metabolism, Microscopy, Electron, Transmission, Microt, TUNEL assay, Ambra1, TOR Serine-Threonine Kinases, drug effect, apoptosis regulatory protein, target of rapamycin kinase, Chloroquine, General Medicine, naphthyridine derivative, unclassified drug, MAP1LC3B protein, human, priority journal, real time polymerase chain reaction, 030220 oncology & carcinogenesis, immunoblotting, Microtubule-Associated Proteins, signal transduction, Signal Transduction, AMBRA1 protein, human, antiproliferative activity, Programmed cell death, autophagy, Cell Survival, galactose, signal transducing adaptor protein, Biology, chemistry, Article, 03 medical and health sciences, transmission electron microscopy, Genetics, medicine, Electron microscopy, controlled study, human, drug screening, Naphthyridines, protein expression, Adaptor Proteins, Signal Transducing, Cell Proliferation, drug resistance, non small cell lung cancer, 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1,6)naphthyridin-2(1H)-one, human cell, tumor cell line, Galactose, Cancer, carbon nuclear magnetic resonance, Triazoles, medicine.disease, 030104 developmental biology, Cancer cell, Cancer research, HCC78 cell line, microtubule associated protein, Apoptosis Regulatory Proteins, metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b49c4e075c2253796d0e5168feb0836Test
https://doi.org/10.1016/j.gene.2019.06.025Test

المؤلفون: Loizidou, Eriketi Z., Zeinalipour-Yazdi, Constantinos D., Christofides, Tasos C., Kostrikis, Leondios G.

المساهمون: Christofides, Tasos C. [0000-0001-6121-0683], Zeinalipour-Yazdi, Constantinos D. [0000-0002-8388-1549], Kostrikis, Leondios G. [0000-0002-5340-7109], Kostrikis, Leontios G. [0000-0002-5340-7109]

المصدر: Bioorganic and Medicinal Chemistry
Bioorg.Med.Chem.

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Resistance, Clinical Biochemistry, Human immunodeficiency virus 1, Quantitative Structure-Activity Relationship, Pharmaceutical Science, Integrase inhibitor, drug protein binding, Carboxamide, HIV Integrase, partition coefficient, Elvitegravir, Biochemistry, Drug Discovery, enzyme inhibition, Autodock, chemistry.chemical_classification, 0303 health sciences, Molecular Structure, biology, octanol, 030302 biochemistry & molecular biology, article, AutoDock, naphthyridine derivative, 3. Good health, Integrase, Enzyme inhibitor, Thermodynamics, Molecular Medicine, quinoline derivative, Protein Binding, medicine.drug, medicine.drug_class, water, 03 medical and health sciences, drug activity, HIV-1 integrase, Drug Resistance, Viral, medicine, HIV Integrase Inhibitors, Molecular Biology, 030304 developmental biology, energy transfer, nonhuman, Inhibitors, Organic Chemistry, integrase inhibitor, Raltegravir, Enzyme, chemistry, HIV-1, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b653a97d22b2ff92a4edb7587ca489dTest
https://doi.org/10.1016/j.bmc.2009.04.058Test

المؤلفون: Elisabetta Mantuano, Clementina Manera, Paola Matarrese, Vincenzo Mattei, Roberta Misasi, Lucrezia Gambardella, Maurizio Sorice, Giuseppe Saccomanni, Antonella Capozzi, Walter Malorni

المصدر: Scopus-Elsevier

مصطلحات موضوعية: Cancer Research, Programmed cell death, topoisomerase ii, Cell Survival, Antineoplastic Agents, Spindle Apparatus, Mitochondrion, Biology, Piperazines, annexin v, microtubules, Inhibitory Concentration 50, mitochondrial membrane potential, hep-2 cells, Cell Line, Tumor, tubulin, naphthyridine derivative, apoptosis, propidium iodide, cytotoxicity, jc-1, cell cycle, bromodeoxyuridine, mitochondria, cancer, Humans, Naphthyridine derivative, Naphthyridines, Mitosis, Laryngeal Neoplasms, Cell Proliferation, Pharmacology, Membrane Potential, Mitochondrial, Cell growth, Carcinoma, Cell cycle, Spindle apparatus, Cell biology, Cell culture, Apoptosis, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e10ac7aa91646594e1fe2046eb6a47Test
http://hdl.handle.net/11568/200346Test

المؤلفون: Clementina Manera, Pier Luigi Ferrarini, Claudio Mori, Muwaffag Badawneh, Mauro Miceli, Flavia Franconi, Giuseppe Saccomanni

المصدر: Il Farmaco. 56:311-318

مصطلحات موضوعية: Blood Platelets, Magnetic Resonance Spectroscopy, Chemical Phenomena, Platelet Aggregation, Spectrophotometry, Infrared, Stereochemistry, Pharmaceutical Science, Human platelet, In Vitro Techniques, Chemical synthesis, Adenylyl cyclase, Structure-Activity Relationship, chemistry.chemical_compound, 8 naphthyridine derivative, Drug Discovery, Cyclic AMP, medicine, Humans, Platelet, Naphthyridines, Papaverine, Arachidonic Acid, Bicyclic molecule, Chemistry, Physical, In vitro, Adenosine Diphosphate, chemistry, Indicators and Reagents, Arachidonic acid, Collagen, Platelet Aggregation Inhibitors, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b4fbf7f6f3de84193ed5c074e5b1b5Test
https://doi.org/10.1016/s0014-827xTest(01)01075-8