المؤلفون: Rodríguez Galindo, Miguel

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

مرشدي الرسالة: Weghorn, Donate

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Selection inference, Somatic evolution, Mutational processes, Cancer, Tumor, Non-coding selection, Somatic variants, Càncer, Genòmica, Inferencia de selecció, Evolució somàtica, Processos mutacionals, Tumors

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/689480Test

المؤلفون: Arnedo Pac, Claudia Rosario

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Medicina i Ciències de la Vida

مرشدي الرسالة: López Bigas, Núria, González Pérez, Abel

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Cancer genomics, Somatic mutations, Mutational processes, Mutational clustering, Mutational hotspots, Genòmica del càncer, Mutacions somàtiques, Processos mutacionals, Aglomeracions mutacionals, Hotspots mutacionals

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/687381Test

المؤلفون: Pich Roselló, Oriol

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

مرشدي الرسالة: López Bigas, Núria, González-Pérez, Abel

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Cancer, Genomics, Evolution, Chemotherapy, Mutational processes càncer, Genòmica, Evolució, Quimioteràpia, Processos mutacionals

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/671532Test

المؤلفون: Frigola Rissech, Joan

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

مرشدي الرسالة: López Bigas, Núria, González Pérez, Abel

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Cancer, Genomics, Mutational processes, Somatic mutations, DNA damage and replay, DNA damage and repair, Cáncer, Genòmica, Mutacions somàtiques, Danys i reparació de l'ADN, Processos mutacionals

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/669530Test

المؤلفون: Gustav Alexander Poulsgaard, Simon Grund Sørensen, Randi Istrup Juul, Morten Muhlig Nielsen, Jakob Skou Pedersen

المصدر: Genome Medicine, Vol 15, Iss 1, Pp 1-19 (2023)

مصطلحات موضوعية: Pan-cancer, Mutational processes, Hotspots, Mutation rate, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-994XTest

الوصول الحر: https://doaj.org/article/6c3345d840ee4c4eafa9b0c2c59bc60bTest

المؤلفون: Robinson, Philip

المساهمون: Stratton, Michael R., Campbell, Peter

مصطلحات موضوعية: somatic mutagenesis, ageing, cancer, mutational processes, intestinal polyposis, inherited cancer predisposition

الوصول الحر: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.857239Test

المؤلفون: Bayarbaatar Amgalan, Damian Wojtowicz, Yoo-Ah Kim, Teresa M. Przytycka

المصدر: Genome Medicine, Vol 15, Iss 1, Pp 1-15 (2023)

مصطلحات موضوعية: Mutational signatures, Networks, Causality inference, Mutational processes in cancer, Breast cancer, APOBEC, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-994XTest

الوصول الحر: https://doaj.org/article/ce5fd6c5e2f447389d4d99f8b2b3bed6Test

المؤلفون: Gerhauser, Clarissa, Favero, Francesco, Risch, Thomas, Simon, Ronald, Feuerbach, Lars, Assenov, Yassen, Heckmann, Doreen, Sidiropoulos, Nikos, Waszak, Sebastian M, Hübschmann, Daniel, Urbanucci, Alfonso, Girma, Etsehiwot G, Kuryshev, Vladimir, Klimczak, Leszek J, Saini, Natalie, Stütz, Adrian M, Weichenhan, Dieter, Böttcher, Lisa-Marie, Toth, Reka, Hendriksen, Josephine D, Koop, Christina, Lutsik, Pavlo, Matzk, Sören, Warnatz, Hans-Jörg, Amstislavskiy, Vyacheslav, Feuerstein, Clarissa, Raeder, Benjamin, Bogatyrova, Olga, Schmitz, Eva-Maria, Hube-Magg, Claudia, Kluth, Martina, Huland, Hartwig, Graefen, Markus, Lawerenz, Chris, Henry, Gervaise H, Yamaguchi, Takafumi N, Malewska, Alicia, Meiners, Jan, Schilling, Daniela, Reisinger, Eva, Eils, Roland, Schlesner, Matthias, Strand, Douglas W, Bristow, Robert G, Boutros, Paul C, von Kalle, Christof, Gordenin, Dmitry, Sültmann, Holger, Brors, Benedikt, Sauter, Guido, Plass, Christoph, Yaspo, Marie-Laure, Korbel, Jan O, Schlomm, Thorsten, Weischenfeldt, Joachim

المصدر: Cancer cell. 34(6)

مصطلحات موضوعية: Humans, Prostatic Neoplasms, RNA-Binding Proteins, Risk Factors, Evolution, Molecular, DNA Methylation, Gene Expression Regulation, Neoplastic, Mutation, Adult, Middle Aged, Male, Transcriptome, Biomarkers, Tumor, Whole Genome Sequencing, APOBEC, cancer genomics, early-onset cancer, epigenetic risk-score, mutational processes, prostate cancer, structural variants, tumor evolution, tumor evolution prediction, Human Genome, Aging, Prevention, Cancer, Urologic Diseases, Prostate Cancer, Genetics, 4.1 Discovery and preclinical testing of markers and technologies, Aetiology, 2.1 Biological and endogenous factors, Detection, screening and diagnosis, Neurosciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8tb3m335Test

المؤلفون: Jing Li, Simon Stenberg, Jia-Xing Yue, Ekaterina Mikhalev, Dawn Thompson, Jonas Warringer, Gianni Liti

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Evolutionary Biology, Cancer, Infectious Diseases, Virology, mutational processes dictating, including mtdna deletions, resolved growth phenotyping, hydroxyurea also induced, mutation rates depended, particularly high occurrence, hydroxyurea mutation footprint, genome instability footprint, dramatic fitness loss, mutation rates, cell growth, %22">xlink ">, wide range, used whole, transversion rate, taken together, study provides, structural variants, remarkable exception, mutagenic effects, marginally affected, important implications

العلاقة: https://figshare.com/articles/journal_contribution/S2_Fig_-/24513877Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1011012.s010Test
https://figshare.com/articles/journal_contribution/S2_Fig_-/24513877Test

المؤلفون: Jing Li, Simon Stenberg, Jia-Xing Yue, Ekaterina Mikhalev, Dawn Thompson, Jonas Warringer, Gianni Liti

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Evolutionary Biology, Cancer, Infectious Diseases, Virology, mutational processes dictating, including mtdna deletions, resolved growth phenotyping, hydroxyurea also induced, mutation rates depended, particularly high occurrence, hydroxyurea mutation footprint, genome instability footprint, dramatic fitness loss, mutation rates, cell growth, %22">xlink ">, wide range, used whole, transversion rate, taken together, study provides, structural variants, remarkable exception, mutagenic effects, marginally affected, important implications

العلاقة: https://figshare.com/articles/journal_contribution/Mutation_rate_estimated_by_fluctuation_assay_in_wildtype_and_four_additional_mutators_in_BY_genetic_background_with_genes_responsible_for_DNA_repair_or_stress_response_deleted_/24513895Test

الإتاحة: https://doi.org/10.1371/journal.pgen.1011012.s016Test
https://figshare.com/articles/journal_contribution/Mutation_rate_estimated_by_fluctuation_assay_in_wildtype_and_four_additional_mutators_in_BY_genetic_background_with_genes_responsible_for_DNA_repair_or_stress_response_deleted_/24513895Test