المؤلفون: Bruno Cesar Costa Soares, Hnin Ei Ei Khine, Boonchoo Sritularak, Pithi Chanvorachote, Rosa Alduina, Rungroch Sungthong, Chatchai Chaotham

المصدر: Frontiers in Pharmacology, Vol 15 (2024)

مصطلحات موضوعية: lung cancer, ROS, apoptosis, mitochondrial outer membrane permeabilization, DNA damage, Cymensifin A, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2024.1361085/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/5541f24e39bd48deaa09a3a4d79e7318Test

المؤلفون: Yiyang Chen, Jesse D. Gelles, Jarvier N. Mohammed, Jerry Edward Chipuk

المصدر: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

مصطلحات موضوعية: apoptosis, BAX, BCL-2 family, mitochondria, mitochondrial outer membrane permeabilization, recombinant protein production, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fcell.2023.1322816/fullTest; https://doaj.org/toc/2296-634XTest

الوصول الحر: https://doaj.org/article/ad1c5e974e5b4f44951c3ad2fc7fdb0eTest

المؤلفون: Prasad Sulkshane, Tanuja Teni

المصدر: Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 3, Pp 278-296 (2022)

مصطلحات موضوعية: myeloid cell leukemia-1, b cell lymphoma-2, mitochondrial outer membrane permeabilization, bcl-2 homology 3 mimetic, therapy resistance, myeloid cell leukemia-1 inhibitor, Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: https://www.explorationpub.com/Journals/etat/Article/100283Test; https://doaj.org/toc/2692-3114Test

الوصول الحر: https://doaj.org/article/93986c4e1e2c4b9ebc28fc2e922f3483Test

المؤلفون: Vitale, Ilio, Pietrocola, Federico, Guilbaud, Emma, Aaronson, Stuart, A, Abrams, John, M, Adam, Dieter, Agostini, Massimiliano, Agostinis, Patrizia, Alnemri, Emad, S, Altucci, Lucia, Amelio, Ivano, Andrews, David, W, Aqeilan, Rami, I, Arama, Eli, Baehrecke, Eric, H, Balachandran, Siddharth, Bano, Daniele, Barlev, Nickolai, A, Bartek, Jiri, Bazan, Nicolas, G, Becker, Christoph, Bernassola, Francesca, Bertrand, Mathieu, J M, Bianchi, Marco, E, Blagosklonny, Mikhail, V, Blander, J. Magarian, Blandino, Giovanni, Blomgren, Klas, Borner, Christoph, Bortner, Carl, D, Bove, Pierluigi, Boya, Patricia, Brenner, Catherine, Broz, Petr, Brunner, Thomas, Damgaard, Rune Busk, Calin, George, A, Campanella, Michelangelo, Candi, Eleonora, Carbone, Michele, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis, Chen, Guo-Qiang, Chen, Quan, Chen, Youhai, H, Cheng, Emily, H, Chipuk, Jerry, E, Cidlowski, John, A, Ciechanover, Aaron, Ciliberto, Gennaro, Conrad, Marcus, Cubillos-Ruiz, Juan, R, Czabotar, Peter, E, D’angiolella, Vincenzo, Daugaard, Mads, Dawson, Ted, M, Dawson, Valina, L, de Maria, Ruggero, de Strooper, Bart, Debatin, Klaus-Michael, Deberardinis, Ralph, J, Degterev, Alexei, del Sal, Giannino, Deshmukh, Mohanish, Di Virgilio, Francesco, Diederich, Marc, Dixon, Scott, J, Dynlacht, Brian, D, El-Deiry, Wafik, S, Elrod, John, W, Engeland, Kurt, Fimia, Gian Maria, Galassi, Claudia, Ganini, Carlo, Garcia-Saez, Ana, J, Garg, Abhishek, D, Garrido, Carmen, Gavathiotis, Evripidis, Gerlic, Motti, Ghosh, Sourav, Green, Douglas, R, Greene, Lloyd, A, Gronemeyer, Hinrich, Häcker, Georg, Hajnóczky, György, Hardwick, J. Marie, Haupt, Ygal, He, Sudan, Heery, David, M, Hengartner, Michael, O, Hetz, Claudio, Hildeman, David, A, Ichijo, Hidenori, Inoue, Satoshi, Jäättelä, Marja, Janic, Ana, Joseph, Bertrand, Jost, Philipp, J, Kanneganti, Thirumala-Devi, Karin, Michael, Kashkar, Hamid, Kaufmann, Thomas, Kelly, Gemma, L, Kepp, Oliver, Kimchi, Adi, Kitsis, Richard, N, Klionsky, Daniel, J, Kluck, Ruth, Krysko, Dmitri, V, Kulms, Dagmar, Kumar, Sharad, Lavandero, Sergio, Lavrik, Inna, N, Lemasters, John, J, Liccardi, Gianmaria, Linkermann, Andreas, Lipton, Stuart, A, Lockshin, Richard, A, López-Otín, Carlos, Luedde, Tom, Macfarlane, Marion, Madeo, Frank, Malorni, Walter, Manic, Gwenola, Mantovani, Roberto, Marchi, Saverio, Marine, Jean-Christophe, Martin, Seamus, J, Martinou, Jean-Claude, Mastroberardino, Pier, G, Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal, Melino, Gerry, Melino, Sonia, Miao, Edward, A, Moll, Ute, M, Muñoz-Pinedo, Cristina, Murphy, Daniel, J, Niklison-Chirou, Maria Victoria, Novelli, Flavia, Núñez, Gabriel, Oberst, Andrew, Ofengeim, Dimitry, Opferman, Joseph, T, Oren, Moshe, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis, Penninger, Josef, M, Pentimalli, Francesca, Pereira, David, M, Pervaiz, Shazib, Peter, Marcus, E, Pinton, Paolo, Porta, Giovanni, Prehn, Jochen, H M, Puthalakath, Hamsa, Rabinovich, Gabriel, A, Rajalingam, Krishnaraj, Ravichandran, Kodi, S, Rehm, Markus, Ricci, Jean-Ehrland, Rizzuto, Rosario, Robinson, Nirmal, Rodrigues, Cecilia, M P, Rotblat, Barak, Rothlin, Carla, V, Rubinsztein, David, C, Rudel, Thomas, Rufini, Alessandro, Ryan, Kevin, M, Sarosiek, Kristopher, A, Sawa, Akira, Sayan, Emre, Schroder, Kate, Scorrano, Luca, Sesti, Federico, Shao, Feng, Shi, Yufang, Sica, Giuseppe, S, Silke, John, Simon, Hans-Uwe, Sistigu, Antonella, Stephanou, Anastasis, Stockwell, Brent, R, Strapazzon, Flavie, Strasser, Andreas, Sun, Liming, Sun, Erwei, Sun, Qiang, Szabadkai, Gyorgy, Tait, Stephen, W G, Tang, Daolin, Tavernarakis, Nektarios, Troy, Carol, M, Turk, Boris, Urbano, Nicoletta, Vandenabeele, Peter, Vanden Berghe, Tom, Vander Heiden, Matthew, G, Vanderluit, Jacqueline, L, Verkhratsky, Alexei, Villunger, Andreas, von Karstedt, Silvia, Voss, Anne, K, Vousden, Karen, H, Vucic, Domagoj, Vuri, Daniela, Wagner, Erwin, F, Walczak, Henning, Wallach, David, Wang, Ruoning, Wang, Ying, Weber, Achim, Wood, Will, Yamazaki, Takahiro, Yang, Huang-Tian, Zakeri, Zahra, Zawacka-Pankau, Joanna, E, Zhang, Lin, Zhang, Haibing, Zhivotovsky, Boris, Zhou, Wenzhao, Piacentini, Mauro, Kroemer, Guido, Galluzzi, Lorenzo

المساهمون: Institut Gustave Roussy (IGR), Métabolisme, Cancer et Immunité (CRC - UMR_S 1138), Institut Gustave Roussy (IGR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut du Cancer Paris CARPEM, Hôpital Européen Georges Pompidou, AP-HP, Paris, France. (CARPEM), ANR-21-ESRE-0028,ONCO-PHENO-SCREEN,Next-generation phenotypic screening for oncological applications(2021)

المصدر: ISSN: 1350-9047.

مصطلحات موضوعية: BAX, BCL2, cancer, death receptors, ischemia, mitochondrial outer membrane permeabilization, stroke, [SDV]Life Sciences [q-bio]

العلاقة: hal-04596448; https://hal.science/hal-04596448Test; https://hal.science/hal-04596448/documentTest; https://hal.science/hal-04596448/file/37100955.pdfTest

الإتاحة: https://doi.org/10.1038/s41418-023-01153-wTest
https://hal.science/hal-04596448Test
https://hal.science/hal-04596448/documentTest
https://hal.science/hal-04596448/file/37100955.pdfTest

المؤلفون: Huiyuan Zheng, Ulla Stenius, Johan Högberg

المصدر: Cancers; Volume 15; Issue 3; Pages: 865

مصطلحات موضوعية: autotaxin (ATX), lysophosphatidic acid (LPA), crystalline silica particles (CSi), endonuclease G (EndoG), mitochondrial outer membrane permeabilization (MOMP), DNA damage, double strand breaks (DSB), micronuclei (MN)

وصف الملف: application/pdf

العلاقة: Molecular Cancer Biology; https://dx.doi.org/10.3390/cancers15030865Test

الإتاحة: https://doi.org/10.3390/cancers15030865Test

المؤلفون: Joshua A. Grosser, Rachel L. Fehrman, Dennis Keefe, Martin Redmon, Robert W. Nickells

المصدر: BMC Research Notes, Vol 14, Iss 1, Pp 1-7 (2021)

مصطلحات موضوعية: BAX, Intrinsic apoptosis, Mitochondrial dysfunction, Mitochondrial outer membrane permeabilization, Mitochondrial fragmentation, Elamipretide (SS31), Medicine, Biology (General), QH301-705.5, Science (General), Q1-390

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-0500Test

الوصول الحر: https://doaj.org/article/a0a3bdfe79184dedbcc355b0d9ece19cTest

المؤلفون: Bruno Cesar Costa Soares, Hnin Ei Ei Khine, Boonchoo Sritularak, Pithi Chanvorachote, Rosa Alduina, Rungroch Sungthong, Chatchai Chaotham

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, lung cancer, ROS, apoptosis, mitochondrial outer membrane permeabilization, DNA damage, Cymensifin A, orchid

العلاقة: https://figshare.com/articles/figure/Image1_Cymensifin_A_a_promising_pharmaceutical_candidate_to_defeat_lung_cancer_via_cellular_reactive_oxygen_species-mediated_apoptosis_pdf/25584228Test

الإتاحة: https://doi.org/10.3389/fphar.2024.1361085.s001Test
https://figshare.com/articles/figure/Image1_Cymensifin_A_a_promising_pharmaceutical_candidate_to_defeat_lung_cancer_via_cellular_reactive_oxygen_species-mediated_apoptosis_pdf/25584228Test

المؤلفون: Joshua A. Grosser (10853724), Rachel L. Fehrman (10853727), Dennis Keefe (8190210), Martin Redmon (10853730), Robert W. Nickells (10853733)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Immunology, Cancer, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, BAX, Intrinsic apoptosis, Mitochondrial dysfunction, Mitochondrial outer membrane permeabilization, Mitochondrial fragmentation, Elamipretide (SS31)

العلاقة: https://figshare.com/articles/journal_contribution/Additional_file_4_of_The_effects_of_a_mitochondrial_targeted_peptide_elamipretide_SS31_on_BAX_recruitment_and_activation_during_apoptosis/14651244Test

الإتاحة: https://doi.org/10.6084/m9.figshare.14651244.v1Test

المؤلفون: Xiaoke Chi, Dang Nguyen, James M Pemberton, Elizabeth J Osterlund, Qian Liu, Hetal Brahmbhatt, Zhi Zhang, Jialing Lin, Brian Leber, David W Andrews

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: primary murine neurons, MEF cells, BMK cells, apoptosis, Bcl-2 family proteins, mitochondrial outer membrane permeabilization, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/44525Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/3930186c3fd04ad4a33907088e2464c2Test

المؤلفون: Alexey S. Ladokhin

المصدر: Cells; Volume 9; Issue 9; Pages: 2121

مصطلحات موضوعية: apoptosis, mitochondrial outer membrane permeabilization, protein–membrane interactions, Bcl-2 proteins as therapeutic targets, cancer

وصف الملف: application/pdf

العلاقة: Cell Signaling; https://dx.doi.org/10.3390/cells9092121Test

الإتاحة: https://doi.org/10.3390/cells9092121Test