المؤلفون: Van Velzen, A.J., Bos, A.C., Touw, D.J., Tiddens, H.A.W.M., Heijerman, H.G.M., Janssens, H.M.

المصدر: Van Velzen , A J , Bos , A C , Touw , D J , Tiddens , H A W M , Heijerman , H G M & Janssens , H M 2016 , ' Pharmacokinetics and Tolerability of Once Daily Double Dose Tobramycin Inhalation in Cystic Fibrosis Using Controlled and Conventional Nebulization ' , Journal of aerosol medicine and pulmonary drug delivery , vol. 29 , no. 3 , pp. 273-280 . https://doi.org/10.1089/jamp.2015.1259Test

مصطلحات موضوعية: cystic fibrosis, inhaled therapy, nebulizer, small airways, adverse drug reaction, airway, clinical article, clinical trial, controlled clinical trial, crossover procedure, exposure, human, human tissue, maximum plasma concentration, medical nebulizer, minimum plasma concentration, pharmacokinetics, randomized controlled trial, safety, tobramycin

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/38f52772-c17a-4a6c-bc8a-57b6df4b0851Test

الإتاحة: https://doi.org/10.1089/jamp.2015.1259Test
https://hdl.handle.net/11370/38f52772-c17a-4a6c-bc8a-57b6df4b0851Test
https://research.rug.nl/en/publications/38f52772-c17a-4a6c-bc8a-57b6df4b0851Test
https://pure.rug.nl/ws/files/79345531/Pharmacokinetics_and_Tolerability_of_Once_Daily_Double_Dose_Tobramycin_Inhalation.pdfTest

المؤلفون: van Wanrooy, Marjolijn J.P., Proost, Johannes H., Rodgers, Michael G. G., Zijlstra, Jan G., Uges, Donald R.A., Kosterink, Jos G.W., van der Werf, Tjip S., Alffenaar, Jan-Willem C.

المصدر: van Wanrooy , M J P , Proost , J H , Rodgers , M G G , Zijlstra , J G , Uges , D R A , Kosterink , J G W , van der Werf , T S & Alffenaar , J-W C 2015 , ' Limited-sampling strategies for anidulafungin in critically ill patients ' , Antimicrobial Agents and Chemotherapy , vol. 59 , no. 2 , pp. 1177-1181 . https://doi.org/10.1128/AAC.03375-14Test

مصطلحات موضوعية: NCT01047267, anidulafungin, adult, aged, area under the curve, article, Bayes theorem, blood sampling, clinical article, compartment model, controlled clinical trial, controlled study, critically ill patient, drug blood level, drug clearance, drug dose increase, drug exposure, drug monitoring, female, human, invasive candidiasis, linear regression analysis, loading drug dose, male, maximum plasma concentration, minimum inhibitory concentration, minimum plasma concentration, pharmacokinetics, plasma concentration-time curve, population model

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/5a5c9067-86cc-495f-83fd-3bdc1c714bedTest

الإتاحة: https://doi.org/10.1128/AAC.03375-14Test
https://hdl.handle.net/11370/5a5c9067-86cc-495f-83fd-3bdc1c714bedTest
https://research.rug.nl/en/publications/5a5c9067-86cc-495f-83fd-3bdc1c714bedTest
https://pure.rug.nl/ws/files/23770981/Antimicrob._Agents_Chemother._2015_van_Wanrooy_1177_81.pdfTest

المؤلفون: Tingbo Liang, Yan Lou, Qingwei Zhao, Xi Yang, Hangping Yao, Rui Luo, Xiaoyang Lu, Xingjiang Hu, Lingjuan He, Lin Liu, Yunqing Qiu, Kaijin Xu, Junwei Su

المصدر: European Journal of Pharmaceutical Sciences

مصطلحات موضوعية: Male, Pharmaceutical Science, 02 engineering and technology, baloxavir marboxil, 030226 pharmacology & pharmacy, law.invention, 0302 clinical medicine, Randomized controlled trial, law, CPK, creatine phosphohykinase, COVID-19, coronavirus disease 2019, LDH, lactate dehydrogenase, Triazines, Standard treatment, Lopinavir, RT-PCR, real-time fluorescent quantitative PCR, Middle Aged, Viral Load, 021001 nanoscience & nanotechnology, ICU, intensive care unit, PCT, procalcitonin, Treatment Outcome, the half-maximal effective concentration (EC50), Pyrazines, CRP, C-reactive protein, Female, Drug Monitoring, Symptom Assessment, AST, Aspartate aminotransferase, 0210 nano-technology, pharmacokinetics, WBC, white blood cell, medicine.drug, Dibenzothiepins, medicine.medical_specialty, Randomization, Coronavirus disease 2019 (COVID-19), Dose, Pyridones, Morpholines, EC50, the half-maximal effective concentration, favipiravir, Favipiravir, Antiviral Agents, Article, Inhibitory Concentration 50, 03 medical and health sciences, Pharmacokinetics, Internal medicine, medicine, Humans, SARS-CoV, Severe Acute Respiratory Syndrome Coronavirus, SARS-CoV-2, business.industry, ALT, Alanine aminotransferase, COVID-19, Amides, COVID-19 Drug Treatment, Clinical trial, Cmin, the minimum plasma concentration, COPD, chronic obstructive pulmonary disease, business, ECMO, extracorporeal membrane oxygenation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce0c457cdb73814169571b11d1a95ccTest

المؤلفون: Frederic Lam, Paul Glue, Chris Gale, C.T. Hung, Noelyn Hung, David B Menkes

المصدر: EBioMedicine, Vol 27, Iss C, Pp 134-137 (2018)
EBioMedicine

مصطلحات موضوعية: Drug, Adult, Male, Bioavailability, media_common.quotation_subject, Cmax, Pharmacokinetic, lcsh:Medicine, Pharmacology, General Biochemistry, Genetics and Molecular Biology, White People, Cmax, maximum plasma concentration, Maori, 03 medical and health sciences, Cmin, Young Adult, 0302 clinical medicine, Pharmacokinetics, medicine, Ethnicity, Humans, Clozapine, Cmin, minimum plasma concentration, media_common, Norclozapine, lcsh:R5-920, business.industry, lcsh:R, AUC0 − τ, area under the curve from time 0 to the end of the dosing interval, General Medicine, Middle Aged, medicine.disease, 030227 psychiatry, Metabolism, Schizophrenia, Toxicity, Female, business, lcsh:Medicine (General), tmax, time to Cmax, 030217 neurology & neurosurgery, medicine.drug, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0391f6049664d464a19c45134f4372f5Test
http://www.sciencedirect.com/science/article/pii/S2352396417304747Test

المؤلفون: Aukje C. Bos, Daan J Touw, Hettie M. Janssens, Harry G.M. Heijerman, A.J. Van Velzen, Harm A.W.M. Tiddens

المساهمون: Pediatrics, Radiology & Nuclear Medicine, Nanomedicine & Drug Targeting, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Groningen Research Institute for Asthma and COPD (GRIAC), Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Medicinal Chemistry and Bioanalysis (MCB)

المصدر: Journal of Aerosol Medicine and Pulmonary Drug Delivery, 29(3), 273-280. Mary Ann Liebert Inc.
Journal of aerosol medicine and pulmonary drug delivery, 29(3), 273-280. MARY ANN LIEBERT, INC

مصطلحات موضوعية: Male, medical nebulizer, Pharmaceutical Science, Cystic fibrosis, cystic fibrosis, 0302 clinical medicine, Tobramycin, Pharmacology (medical), 030212 general & internal medicine, Lung, Netherlands, small airways, clinical article, Cross-Over Studies, Inhalation, inhaled therapy, clinical trial, Middle Aged, Anti-Bacterial Agents, Treatment Outcome, Tolerability, Patient Satisfaction, Anesthesia, Female, Drug Monitoring, pharmacokinetics, medicine.drug, Pulmonary and Respiratory Medicine, Adult, safety, crossover procedure, adverse drug reaction, nebulizer, tobramycin, Drug Administration Schedule, 03 medical and health sciences, Young Adult, Pharmacokinetics, Administration, Inhalation, medicine, Humans, human, Adverse effect, controlled clinical trial, business.industry, maximum plasma concentration, Nebulizers and Vaporizers, medicine.disease, Crossover study, minimum plasma concentration, human tissue, Nebulizer, 030228 respiratory system, airway, exposure, randomized controlled trial, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a624feca6cf3ed8f5d3d1b611e733ec5Test
https://doi.org/10.1089/jamp.2015.1259Test

المؤلفون: Corcione, S., D'Avolio, A., Allegra, S., Fanelli, V., Urbino, R., Ranieri, M. V., Di Perri, G., De Rosa, F. G.

المساهمون: Corcione, S., D'Avolio, A., Allegra, S., Fanelli, V., Urbino, R., Ranieri, M.V., Di Perri, G., De Rosa, F.G.

مصطلحات موضوعية: linezolid, antiinfective agent, adult, adult respiratory distress syndrome, aged, area under the curve, clinical article, continuous hemofiltration, controlled study, critically ill patient, drug blood level, drug clearance, drug distribution, drug half life, female, hospital acquired pneumonia, human, Italy, Letter, male, maximum plasma concentration, middle aged, minimum inhibitory concentration, minimum plasma concentration, priority journal, prospective study, Staphylococcus aureu, steady state, ventilator associated pneumonia, very elderly

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000402468100021; volume:49; issue:6; firstpage:784; lastpage:785; numberofpages:2; journal:INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS; http://hdl.handle.net/11585/663685Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85018187096; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018187096&doi=10.1016%2fj.ijantimicag.2017.04.002&partnerID=40&md5=dc7ef8763a0cfc5d31665a9803d09f71Test

الإتاحة: https://doi.org/10.1016/j.ijantimicag.2017.04.002Test
http://hdl.handle.net/11585/663685Test

المؤلفون: Rosario Urbino, Marco Ranieri, Antonio D'Avolio, Silvia Corcione, Vito Fanelli, Giovanni Di Perri, Sarah Allegra, Francesco Giuseppe De Rosa

المساهمون: Corcione, S., D'Avolio, A., Allegra, S., Fanelli, V., Urbino, R., Ranieri, M.V., Di Perri, G., De Rosa, F.G.

المصدر: International Journal of Antimicrobial Agents. 49:784-785

مصطلحات موضوعية: Male, 0301 basic medicine, Letter, very elderly, medicine.medical_treatment, intensive care unit, 030226 pharmacology & pharmacy, Plasma, chemistry.chemical_compound, 0302 clinical medicine, Pharmacology (medical), Infusions, Intravenou, Prospective Studies, Infusions, Intravenous, Chromatography, High Pressure Liquid, Aged, 80 and over, Continuous venovenous haemofiltration, clinical article, critical illne, General Medicine, adult respiratory distress syndrome, Middle Aged, Anti-Bacterial Agents, antiinfective agent, drug distribution, intravenous drug administration, Intensive Care Units, Infectious Diseases, priority journal, Italy, Plasma chemistry, Staphylococcus aureu, Female, prospective study, Human, Adult, Microbiology (medical), medicine.medical_specialty, high performance liquid chromatography, area under the curve, Critical Illness, 030106 microbiology, MEDLINE, minimum inhibitory concentration, chemistry, drug clearance, Young Adult, 03 medical and health sciences, critically ill patient, Pharmacokinetics, Anti-Bacterial Agent, Hemofiltration, medicine, Humans, controlled study, steady state, Intensive care medicine, Aged, continuous hemofiltration, maximum plasma concentration, Critically ill, business.industry, drug half life, Linezolid, Pneumonia, minimum plasma concentration, Prospective Studie, hospital acquired pneumonia, linezolid, adult, drug blood level, Critical illness, pneumonia, Adult, ventilator associated pneumonia, business

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d0809881288150304636206eae9fa0Test
https://doi.org/10.1016/j.ijantimicag.2017.04.002Test

المؤلفون: Corcione, S., Pagani, N., Baietto, L., Fanelli, V., Urbino, R., Ranieri, V. M., Di Perri, G., D'Avolio, A., De Rosa, F. G.

المساهمون: Corcione, S., Pagani, N., Baietto, L., Fanelli, V., Urbino, R., Ranieri, V.M., Di Perri, G., D'Avolio, A., De Rosa, F.G.

مصطلحات موضوعية: linezolid, antiinfective agent, acute respiratory failure, adult, area under the curve, bloodstream infection, body ma, body size, case report, community acquired pneumonia, drug clearance, drug half life, drug megadose, health care associated pneumonia, human, hypercapnia, Letter, lung lavage, male, maximum plasma concentration, methicillin resistant Staphylococcus aureu, methicillin-resistant Staphylococcus epidermidi, middle aged, minimum inhibitory concentration, minimum plasma concentration, morbid obesity, plasma clearance, respiratory failure, sepsi, septic shock

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000359723600040; volume:70; issue:8; firstpage:2417; lastpage:2418; numberofpages:2; journal:JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY; http://hdl.handle.net/11585/663693Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84939496016; https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939496016&doi=10.1093%2fjac%2fdkv126&partnerID=40&md5=92e13eb5249fb78ecc4f44935fa4bbebTest

الإتاحة: https://doi.org/10.1093/jac/dkv126Test
http://hdl.handle.net/11585/663693Test

المؤلفون: Donald R. A. Uges, Marjolijn J. P. van Wanrooy, Michael G. G. Rodgers, Jos G. W. Kosterink, Tjip S. van der Werf, Johannes H. Proost, Jan G. Zijlstra, Jan-Willem C. Alffenaar

المساهمون: Nanomedicine & Drug Targeting, Biopharmaceuticals, Discovery, Design and Delivery (BDDD), Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE)

المصدر: Antimicrobial Agents and Chemotherapy, 59(2), 1177-1181. AMER SOC MICROBIOLOGY

مصطلحات موضوعية: Bayes theorem, loading drug dose, NCT01047267, Bayes' theorem, Echinocandins, Statistics, Pharmacology (medical), Prospective Studies, population model, drug monitoring, education.field_of_study, clinical article, medicine.diagnostic_test, adult, Area under the curve, article, Middle Aged, invasive candidiasis, aged, Infectious Diseases, female, priority journal, blood sampling, pharmacokinetics, medicine.drug, drug dose increase, medicine.medical_specialty, drug exposure, area under the curve, Critical Illness, Population, Clinical Therapeutics, minimum inhibitory concentration, anidulafungin, drug clearance, Young Adult, critically ill patient, Pharmacokinetics, male, Linear regression, medicine, Humans, Candidiasis, Invasive, controlled study, human, Intensive care medicine, education, Pharmacology, controlled clinical trial, business.industry, maximum plasma concentration, prediction, compartment model, minimum plasma concentration, Therapeutic drug monitoring, drug blood level, linear regression analysis, Anidulafungin, business, plasma concentration-time curve, Blood sampling

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654fdfed85bde3acd4c63276996847eeTest
https://research.rug.nl/en/publications/5a5c9067-86cc-495f-83fd-3bdc1c714bedTest

المؤلفون: Antonio D'Avolio, V. Marco Ranieri, Vito Fanelli, Lorena Baietto, Francesco Giuseppe De Rosa, Giovanni Di Perri, Silvia Corcione, Rosario Urbino, Nicole Pagani

المساهمون: Corcione, S., Pagani, N., Baietto, L., Fanelli, V., Urbino, R., Ranieri, V.M., Di Perri, G., D'Avolio, A., De Rosa, F.G.

مصطلحات موضوعية: Male, drug megadose, obesity, Letter, ultra performance liquid chromatography, Gastroenterology, lung lavage, chemistry.chemical_compound, Plasma, middle aged, Pharmacology (medical), linezolid, acute respiratory failure, plasma clearance, Volume of distribution, adult, Obesity, Morbid, antiinfective agent, Infectious Diseases, sepsi, ICU, PK/PD, TDM, Microbiology (medical), medicine.medical_specialty, area under the curve, Cmax, Renal function, bloodstream infection, complication, linezolid, minimum inhibitory concentration, chemistry, drug clearance, Cmin, Pharmacokinetics, methicillin resistant Staphylococcus aureu, Internal medicine, medicine, case report, human, methicillin-resistant Staphylococcus epidermidi, PK/PD models, Staphylococcal Infection, Pharmacology, health care associated pneumonia, business.industry, maximum plasma concentration, drug half life, respiratory failure, community acquired pneumonia, hypercapnia, Staphylococcal Infections, Anti-Bacterial Agent, minimum plasma concentration, morbid obesity, Pharmacodynamics, Linezolid, septic shock, business, body size, body ma

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2e66aadc0d63eaed7b4236fc891498Test
http://hdl.handle.net/2318/1529180Test