التفاصيل البيبلوغرافية
| العنوان: |
Transcriptomic landscapes of effective and failed liver regeneration in humans. |
| المؤلفون: |
Starlinger, Patrick, Brunnthaler, Laura, McCabe, Chantal, Pereyra, David, Santol, Jonas, Steadman, Jessica, Hackl, Matthias, Skalicky, Susanna, Hackl, Hubert, Gronauer, Raphael, O'Brien, Daniel, Kain, Renate, Hirsova, Petra, Gores, Gregory J, Wang, Chen, Gruenberger, Thomas, Smoot, Rory L, Assinger, Alice |
| المصدر: |
JHEP Rep ; ISSN:2589-5559 ; Volume:5 ; Issue:4 |
| بيانات النشر: |
PubMed Central |
| سنة النشر: |
2023 |
| المجموعة: |
PubMed Central (PMC) |
| مصطلحات موضوعية: |
ALT, alanine aminotransferase, AST, aspartate aminotransferase, CASH, chemotherapy associated steatohepatitis, DLR, dysfunctional LR, DUSP-4, DUSP4, dual-specificity phosphatase 4, FDR, false discovery rate, FLR, functional LR, FPKM, fragments per kilobase of transcript per million mapped reads, Human, ICAM-1, intracellular adhesion molecule-1, IPA, Ingenuity Pathway Analysis, IVCL, inferior vena cava ligation, Inflammation, LPS, lipopolysaccharide, LR, liver regeneration, LSEC, liver sinusoidal endothelial cell, Liver regeneration, MFI, mean fluorescence intensity, MPO, myeloperoxidase, NASH, non-alcoholic steatohepatitis, Neutrophils, PCA, principal component analysis, POD1, 1 day after liver resection, POD5, 5 days after liver resection, STRING, Search Tool for the Retrieval of Interacting Genes/Proteins, TMM, trimmed mean of M values, TNF, tumour necrosis factor, logCPM, log counts per million, pTPM, protein-coding transcripts per million |
| الوصف: |
Although extensive experimental evidence on the process of liver regeneration exists, in humans, validation is largely missing. However, liver regeneration is critically affected by underlying liver disease. Within this project, we aimed to systematically assess early transcriptional changes during liver regeneration in humans and further assess how these processes differ in people with dysfunctional liver regeneration. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| العلاقة: |
https://doi.org/10.1016/j.jhepr.2023.100683Test; https://pubmed.ncbi.nlm.nih.gov/36950091Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025111Test/ |
| DOI: |
10.1016/j.jhepr.2023.100683 |
| الإتاحة: |
https://doi.org/10.1016/j.jhepr.2023.100683Test
https://pubmed.ncbi.nlm.nih.gov/36950091Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10025111Test/ |
| حقوق: |
© 2023 The Author(s). |
| رقم الانضمام: |
edsbas.E5640ABA |
| قاعدة البيانات: |
BASE |
