دورية أكاديمية
Intermolecular Organophotocatalytic Cyclopropanation of Unactivated Olefins
| العنوان: | Intermolecular Organophotocatalytic Cyclopropanation of Unactivated Olefins |
|---|---|
| المؤلفون: | David M. Fischer (12511020), Henry Lindner (14341130), Willi M. Amberg (10886188), Erick M. Carreira (1330920) |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Biophysics, Biochemistry, Medicine, Ecology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, quantum yield determination, intermolecular organophotocatalytic cyclopropanation, trisubstituted olefins, mechanistic investigations, deuteration experiments, catalytic cycle, 5 mol |
| الوصف: | Intermolecular cyclopropanation of mono-, di-, and trisubstituted olefins with α-bromo-β-ketoesters and α-bromomalonates under organophotocatalysis is reported. The reaction displays broad functional group tolerance, including substrates bearing acids, alcohols, halides, ethers, ketones, nitriles, esters, amides, carbamates, silanes, stannanes, boronic esters, as well as arenes, and furnishes highly substituted cyclopropanes. The transformation may be performed in the presence of air and moisture with 0.5 mol % of a benzothiazinoquinoxaline as organophotocatalyst. Mechanistic investigations, involving Stern–Volmer quenching, quantum yield determination, and deuteration experiments, are carried out, and a catalytic cycle for the transformation is discussed. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | https://figshare.com/articles/journal_contribution/Intermolecular_Organophotocatalytic_Cyclopropanation_of_Unactivated_Olefins/21830933Test |
| DOI: | 10.1021/jacs.2c11680.s001 |
| الإتاحة: | https://doi.org/10.1021/jacs.2c11680.s001Test |
| حقوق: | CC BY-NC 4.0 |
| رقم الانضمام: | edsbas.1175E8FA |
| قاعدة البيانات: | BASE |
| DOI: | 10.1021/jacs.2c11680.s001 |
|---|