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1دورية أكاديمية
المؤلفون: Fubiao Shi
المصدر: Frontiers in Physiology, Vol 15 (2024)
مصطلحات موضوعية: salt-inducible kinases, cardiovascular disease, metabolic syndrome, inflammation, fibrosis, SIK inhibitors, Physiology, QP1-981
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/fphys.2024.1426244/fullTest; https://doaj.org/toc/1664-042XTest
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2دورية أكاديمية
المؤلفون: Lixuan Peng, Cai Li, Xiaohan Tang, Yuyan Xiang, Yang Xu, Wenyu Cao, Huamao Zhou, Suyun Li
المصدر: Brain and Behavior, Vol 13, Iss 12, Pp n/a-n/a (2023)
مصطلحات موضوعية: epilepsy, neuronal activation, salt‐inducible kinases, YKL‐06‐061, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/2162-3279Test
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3دورية أكاديمية
المؤلفون: Mohammad Abdolvand, Zahra Mohammadi Chermahini, Sahar Bahaloo, Mohammad Hassan Emami, Alireza Fahim, Hojjatolah Rahimi, Elham Amjadi, Fatemeh Maghool, Fattah Rohani, Mina Dadkhah, Nooshin Farhadian, Nasimeh Vatandoust, Shirin Abdolvand, Maliheh Roozbahani Darehsari, Mohammad Chehelgerdi, Faeze Ahmadi Beni, Mahsa Khodadoostan, Simin Hemati, Mansoor Salehi
المصدر: Journal of Research in Medical Sciences, Vol 29, Iss 1, Pp 10-10 (2024)
مصطلحات موضوعية: colorectal cancer, linc01282, lnc-myadm-1:1, micrornas-616-3p, salt-inducible kinases 1, znf347, Medicine
وصف الملف: electronic resource
العلاقة: http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2024;volume=29;issue=1;spage=10;epage=10;aulast=AbdolvandTest; https://doaj.org/toc/1735-1995Test; https://doaj.org/toc/1735-7136Test
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4دورية أكاديمية
المؤلفون: Taouès Temal-Laib, Christophe Peixoto, Nicolas Desroy, Elsa De Lemos, Florence Bonnaterre, Natacha Bienvenu, Olivier Picolet, Eric Sartori, Denis Bucher, Miriam López-Ramos, Carlos Roca Magadán, Wendy Laenen, Thomas Flower, Patrick Mollat, Olivier Bugaud, Robert Touitou, Anna Pereira Fernandes, Stephanie Lavazais, Alain Monjardet, Monica Borgonovi, Romain Gosmini, Reginald Brys, David Amantini, Steve De Vos, Martin Andrews
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Cancer, Inorganic Chemistry, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, throughput screening campaign, protein kinase amp, activated protein kinase, immunoregulatory cytokine production, clinical candidate glpg3312, pharmacokinetic investigations led, pharmacokinetic properties, immunoregulatory activities, glpg3312 demonstrated, vivo <, vitro <, threonine kinases, therapeutic potential, subsequent hit, sik inhibitor, mouse models, inducible kinases, dual mechanism
الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01428.s001Test
https://figshare.com/articles/journal_contribution/Optimization_of_Selectivity_and_Pharmacokinetic_Properties_of_Salt_Inducible_Kinase_Inhibitors_that_Led_to_the_Discovery_of_Pan-SIK_Inhibitor_GLPG3312/24904973Test -
5
المؤلفون: Hsu, Austin
مصطلحات موضوعية: Biology, Cellular biology, Physiology, Cardiac biology, Cardiac hypertrophy, Heart failure, Salt inducible kinases, Signaling, Transcription
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/8nx083w3Test
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6دورية أكاديمية
المؤلفون: Heap, Rachel E., Hope, Anthony G., Pearson, Lesley-Anne, Reyskens, Kathleen M. S. E., McElroy, Stuart P., Hastie, C. James, Porter, David W., Arthur, J. Simon C., Gray, David W., Trost, Matthias
المصدر: Heap , R E , Hope , A G , Pearson , L-A , Reyskens , K M S E , McElroy , S P , Hastie , C J , Porter , D W , Arthur , J S C , Gray , D W & Trost , M 2017 , ' Identifying Inhibitors of Inflammation : A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs) ' , SLAS Discovery , vol. 22 , no. 10 , pp. 1193-1202 . https://doi.org/10.1177/2472555217717473Test
مصطلحات موضوعية: Journal article, MALDI TOF, Mass spectrometry, Salt inducible kinases, Kinase, High-throughput screen, Inflammation, Drug discovery, Macrophage, Interleukin-10
وصف الملف: application/pdf
الإتاحة: https://doi.org/10.1177/2472555217717473Test
https://discovery.dundee.ac.uk/en/publications/aea1bf92-f989-45f0-b815-d55e1584cd30Test
https://discovery.dundee.ac.uk/ws/files/17369126/2472555217717473.pdfTest -
7تقرير
المؤلفون: Tang, Hei-Man Vincent, Gao, Wei-Wei, Chan, Ching-Ping, Siu, Yeung-Tung, Wong, Chi-Ming, Kok, Kin-Hang, Ching, Yick-Pang, Takemori, Hiroshi, Jin, Dong-Yan
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8
المؤلفون: Ozanne, James, Prescott, Alan R., Clark, Kristopher
المصدر: Biochemical Journal
مصطلحات موضوعية: salt-inducible kinase, interleukin-10, Dasatinib, HDAC, histone deacetylase, DMEM, Dulbecco’s modified Eagle’s medium, M-CSF, macrophage colony-stimulating factor, CREB, cAMP-response-element-binding protein, Mice, hemic and lymphatic diseases, ERK 1/2, extracellular-signal-regulated kinase 1/2, IKK, IκB kinase, Cyclic AMP Response Element-Binding Protein, IκB, inhibitor of NF-κB, Cells, Cultured, MSK, mitogen- and stress-activated protein kinases, HA, haemagglutinin, Aniline Compounds, qPCR, quantitative real-time PCR, CRTC, CREB-regulated transcription co-activator, Pam3CSK4, tripalmitoylcysteinylseryl-(lysyl)4, Phosphotransferases (Alcohol Group Acceptor), GAPDH, glyceraldehyde-3-phosphate dehydrogenase, SIK, salt-inducible kinases, JNK, c-Jun N-terminal kinase, Quinolines, LPS, lipopolysaccharide, Cytokines, NF-κB, nuclear factor κB, Research Article, TLR, Toll-like receptor, Tumor Necrosis Factor Ligand Superfamily Member 14, Btk, Bruton’s tyrosine kinase, chemical biology, bosutinib, Protein Serine-Threonine Kinases, Nitriles, PGE2, prostaglandin E2, Animals, Protein Kinase Inhibitors, Arginase, Macrophages, Immunity, Innate, IL, interleukin, Thiazoles, Pyrimidines, inflammation, TBK1, TANK-binding kinase 1, MAPK, mitogen-activated protein kinase, IRF, interferon regulatory factor, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::582c64aa1317d6ccb69afb9b6b343395Test
http://europepmc.org/articles/PMC4286194Test -
9دورية أكاديمية
المؤلفون: Novák, J. (Jakub), Fabrik, I., Linhartová, I. (Irena), Link, M., Černý, O. (Ondřej), Stulík, J., Šebo, P. (Peter)
مصطلحات موضوعية: GTPASE-ACTIVATING-PROTEIN, SALT-INDUCIBLE KINASES, GENE ONTOLOGY
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29176673; urn:pissn: 2045-2322; urn:eissn: 2045-2322; http://hdl.handle.net/11104/0279008Test
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10
المؤلفون: Lesley-Anne Pearson, David W. Gray, Rachel E. Heap, Anthony G. Hope, Kathleen M. S. E. Reyskens, C. James Hastie, J. Simon C. Arthur, Matthias Trost, Stuart P. McElroy, David W. Porter
المصدر: Slas Discovery
مصطلحات موضوعية: 0301 basic medicine, kinase, interleukin-10, Inflammation, Peptide, macrophage, Biology, Protein Serine-Threonine Kinases, Mass spectrometry, 01 natural sciences, Biochemistry, Analytical Chemistry, drug discovery, 03 medical and health sciences, salt inducible kinases, medicine, Humans, high-throughput screen, IC50, Protein Kinase Inhibitors, Original Research, mass spectrometry, chemistry.chemical_classification, Cell Nucleus, Drug discovery, Kinase, Cellular Assay, Molecular biology, In vitro, 0104 chemical sciences, 3. Good health, High-Throughput Screening Assays, 010404 medicinal & biomolecular chemistry, Protein Transport, 030104 developmental biology, chemistry, MALDI TOF, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Molecular Medicine, medicine.symptom, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e26650346a1cd45eb0c95de04f2b1eTest
https://pubmed.ncbi.nlm.nih.gov/28692323Test