المؤلفون: Xu G, Wang J, Zhang Y, Chen Z, Deng R

المصدر: Eye and Brain, Vol Volume 15, Pp 139-151 (2023)

مصطلحات موضوعية: glaucoma, gamma-glutamyl transpeptidase 1, ferroptosis, autophagy, glutamate cysteine ligase catalytic subunit, Ophthalmology, RE1-994, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/ggt1-suppresses-the-development-of-ferroptosis-and-autophagy-in-mouse--peer-reviewed-fulltext-article-EBTest; https://doaj.org/toc/1179-2744Test

الوصول الحر: https://doaj.org/article/05b30b5d8d8744f08f48f732f6693014Test

المؤلفون: Zhan, Yongqiang, Xu, Dongwei, Tian, Yizhu, Qu, Xiaoye, Sheng, Mingwei, Lin, Yuanbang, Ke, Michael, Jiang, Longfeng, Xia, Qiang, Kaldas, Fady M, Farmer, Douglas G, Ke, Bibo

المصدر: JHEP reports : innovation in hepatology. 4(9)

مصطلحات موضوعية: ALT, alanine aminotransferase, APAF1, apoptotic peptidase activating factor 1, ASK1, apoptosis signal-regulating kinase 1, AST, aspartate aminotransferase, Apoptosis, BMM, bone marrow-derived macrophage, CXCL-10, C-X-C motif chemokine ligand 10, CYLD, cyclindromatosis, ChIP, chromatin immunoprecipitation, DAMP, damage-associated molecular pattern, DUB, deubiquitinating enzyme, ER, endoplasmic reticulum, ES, embryonic stem, G3BP1, G3BP1, Ras GTPase-activating protein-binding protein 1, GCLC, glutamate-cysteine ligase catalytic subunit, GCLM, glutamate-cysteine ligase regulatory subunit, IHC, immunohistochemistry, INF-β, interferon-β, IR, ischaemia/reperfusion, IRF3, IRF3, interferon regulatory factor 3, IRF7, IFN-regulating transcription factor 7, IRI, ischaemia/reperfusion injury, Innate immunity, KO, knockout, LPS, lipopolysaccharide, Liver inflammation, Lyz2, Lysozyme 2, MCP-1, monocyte chemoattractant protein 1, NOX2, NADPH oxidase 2, NOX4, NADPH oxidase 4, NQO1, NAD(P)H quinone dehydrogenase 1, NRF2, nuclear factor (erythroid-derived 2)-like 2, NS, non-specific, Necroptosis, OASL1, 2′, 5′oligoadenylate synthetase-like 1, PAMP, pathogen-derived molecular pattern, RIPK3, receptor-interacting serine/threonine-protein kinase 3, ROS, reactive oxygen species, STING, STING, stimulator of interferon genes, TBK1, TANK-binding kinase 1, TLR4, Toll-like receptor 4, TNF-α, tumour necrosis factor-alpha, TRX, thioredoxin, TSS, transcription start sites, TXNIP, thioredoxin-interacting protein, TXNIPFL/FL, floxed TXNIP, TXNIPM-KO, myeloid-specific TXNIP KO, UTR, untranslated region, sALT, serum ALT, sAST, serum AST, siRNA, small interfering RNA, Liver Disease, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/54g9807fTest

المؤلفون: Lastres-Becker, I., Morgenstern, C., Demirdögen, B.C., Costa, V.M., Daiber, A., Foresti, R., Motterlini, R.

مصطلحات موضوعية: NRF2, HMOX1 gene, human, nonhuman, NQO1 gene, Nrf2 signaling, oxidative stress, protein function, Review, SRXN1 gene, translational research, TXNRD1 gene, Biomarker, Oxidative stress response, Target genes, Transcription factor, biological marker, glutamate cysteine ligase, glutamate cysteine ligase catalytic subunit, glutamate cysteine ligase modifier subunit, heme oxygenase 1, nicotinamide adenine dinucleotide phosphate quinone dehydrogenase 1, reduced nicotinamide adenine dinucleotide phosphate dehydrogenase, sulfiredoxin 1, thioredoxin reductase 1, transcription factor Nrf2, unclassified drug, body fluid, cell protection, GCLC gene

العلاقة: Redox Biology; DiÄŸer; https://doi.org/10.1016/j.redox.2024.103134Test; https://hdl.handle.net/20.500.11851/11559Test; 72; WOS:001233628200001; 2-s2.0-85190738421

الإتاحة: https://doi.org/20.500.11851/1155910.1016/j.redox.2024.103134Test
https://hdl.handle.net/20.500.11851/11559Test

المؤلفون: Na Fu, Dongdong Li, Wencong Li, Wen Zhao, Siyu Zhang, Lingdi Liu, Suxian Zhao, Jinghua Du, Lingbo Kong, Rongqi Wang, Yuguo Zhang, Yuemin Nan

المصدر: Frontiers in Molecular Biosciences, Vol 7 (2020)

مصطلحات موضوعية: glutamate-cysteine ligase catalytic subunit, hepatitis C virus, liver fibrosis, hepatic stellate cells, endoplasmic reticulum stress, oxidative stress, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fmolb.2020.00199/fullTest; https://doaj.org/toc/2296-889XTest

الوصول الحر: https://doaj.org/article/d0ee284b1333457d882f33151f608907Test

المؤلفون: Jeong-Woong Park, Jae-Young Choi, Seul A Hong, Nam Young Kim, Kyoung-Tag Do, Ki-Duk Song, Byung-Wook Cho

المصدر: Asian-Australasian Journal of Animal Sciences, Vol 30, Iss 5, Pp 728-735 (2017)

مصطلحات موضوعية: Horse, Exercise, Glutamate-cysteine Ligase Catalytic Subunit (), Glutamate-cysteine Ligase Modifier Subunit (), Quantitative Polymerase Chain Reaction, Animal culture, SF1-1100, Animal biochemistry, QP501-801

وصف الملف: electronic resource

العلاقة: http://www.ajas.info/upload/pdf/ajas-30-5-728.pdfTest; https://doaj.org/toc/1011-2367Test; https://doaj.org/toc/1976-5517Test

الوصول الحر: https://doaj.org/article/02052f09c83b4c7eb38e3045f6293366Test

المؤلفون: Dai, Lixing, Diao, Ruiqing, Zhang, Jinghua, Cao, Mengying, Gao, Hongli, Tang, Bibo

المصدر: Tropical Journal of Pharmaceutical Research; Vol. 20 No. 5 (2021); 893-898

مصطلحات موضوعية: nervous system, cardiovascular system, Pharmaceutical Science, heterocyclic compounds, Pharmacology (medical), Tetramethyl pyrazine, Bax, Bcl-2, Nrf2, glutamate-cysteine ligase catalytic subunit, MPTP, Parkinsonism, nervous system diseases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f220825119a546361d609db8cbf2f6Test
https://doi.org/10.4314/tjpr.v20i5.2Test

المؤلفون: Hai-Yong Chen, Yibin Feng, Cheng Zhang, Ning Wang, Sha Li, Guoyi Tang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)

مصطلحات موضوعية: LOX1, lectin-like oxidized LDL receptor 1, BUN, blood urea nitrogen, TGBM, thickness of glomerular basement membrane, NQO1, NAD(P)H:quinone oxidoreductase 1, STAT, signal transducers and activators of transcription, N/O, not observed, p62, sequestosome 1 protein, p-IRS1, phospho-IRS1, Review, NOX-4, nicotinamide adenine dinucleotide phosphate-oxidase-4, OCP, oxidative carbonyl protein, Traditional Chinese medicine, AGEs, advanced glycation end-products, N/A, not applicable, TRAF5, tumor-necrosis factor receptor-associated factor 5, Health problems, 0302 clinical medicine, ESRD, end-stage renal disease, LDL, low-density lipoprotein, BMP-7, bone morphogenetic protein-7, TGFβR-I/II, TGF-β receptor I/II, Medicine, P70S6K, 70-kDa ribosomal protein S6 kinase, General Pharmacology, Toxicology and Pharmaceutics, SOCS, suppressor of cytokine signaling proteins, HO-1, heme oxygenase-1, 0303 health sciences, TG, triglyceride, BW, body weight, HDL-C, high density lipoprotein-cholesterol, RASI, renin-angiotensin system inhibitor, ATK, protein kinase B, TBARS, thiobarbituric acid-reactive substance, BCL-XL, B-cell lymphoma-extra large, Gαq, Gq protein alpha subunit, GCK, glucokinase, PI3K, phosphatidylinositol 3 kinases, Systematic review, TLR-2/4, toll-like receptor 2/4, IR, insulin receptor, PERK, protein kinase RNA-like eukaryotic initiation factor 2A kinase, 030220 oncology & carcinogenesis, CRP, C-reactive protein, IRS, insulin receptor substrate, AM, mesangial area, JAK, Janus kinase, FBG, fasting blood glucose, ETAR, endothelium A receptor, LDL-C, low density lipoprotein-cholesterol, CD2AP, CD2-associated protein, eIF2α, eukaryotic initiation factor 2α, RM1-950, mTOR, mammalian target of rapamycin, CHOP, C/EBP homologous protein, STZ, streptozotocin, 03 medical and health sciences, ADE, adverse event, PKC, protein kinase C, LC3, microtubule-associated protein light chain 3, ORP150, 150-kDa oxygen-regulated protein, PGE2, prostaglandin E2, IL-1β/6, interleukin 1β/6, Diabetic kidney disease, IGF-1, insulin-like growth factor 1, EP, E-prostanoid receptor, FN, fibronectin, eGFR, estimated GFR, MDA, malondialdehyde, Chinese medicine, MMP-2, matrix metallopeptidase 2, XBP-1, spliced X box-binding protein 1, TGF-β, tumor growth factor β, GRB 10, growth factor receptor-bound protein 10, medicine.disease, Clinical trial, GRP78, glucose-regulated protein 78, UP, urinary protein, IGF-1R, insulin-like growth factor 1 receptor, ACEI, angiotensin-converting enzyme inhibitor, BCL-2, B-cell lymphoma 2, EMT, epithelial-to-mesenchymal transition, MAPK, mitogen-activated protein kinase, MYD88, myeloid differentiation primary response 88, PBG, postprandial blood glucose, RCT, randomized clinical trial, N/R, not reported, COL-I/IV, collagen I/IV, PINK1, PTEN-induced putative kinase 1, UACR, urinary albumin to creatinine ratio, C, control group, Diabetic nephropathy, GPX, glutathione peroxidase, ICAM-1, intercellular adhesion molecule-1, Bioinformatics, VCAM-1, vascular cell adhesion molecule-1, AMPKα, adenosine monophosphate-activated protein kinase α, DM, diabetes mellitus, TFEB, transcription factor EB, TNF-α, tumor necrosis factor α, Molecular target, IKK-β, IκB kinase β, Signaling pathway, GLUT4, glucose transporter type 4, BAX, BCL-2-associated X protein, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, PARP, poly(ADP-Ribose) polymerase, SMURF-2, SMAD ubiquitination regulatory factor 2, AREs, antioxidant response elements, MD, mean difference, SMAD, small mothers against decapentaplegic, MCP-1, monocyte chemotactic protein-1, VEGF, vascular endothelial growth factor, cAMP, cyclic adenosine monophosphate, ARB, angiotensin receptor blocker, PAI-1, plasminogen activator inhibitor-1, SMD, standard mean difference, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, IκB-α, inhibitory protein α, Herbal medicine, TCM, traditional Chinese medicine, DG, glomerular diameter, GSK-3, glycogen synthase kinase 3, SIRT1, sirtuin 1, D, duration, HbA1c, glycosylated hemoglobin, WMD, weight mean difference, CTGF, connective tissue growth factor, ER, endoplasmic reticulum, DN, diabetic nephropathy, ROS, reactive oxygen species, CCR, creatinine clearance rate, SOD, superoxide dismutase, Diabetes mellitus, PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1α, ET-1, endothelin-1, UMA, urinary microalbumin, SCr, serum creatinine, IRE-1α, inositol-requiring enzyme-1α, 030304 developmental biology, TII, tubulointerstitial injury index, RAGE, receptors of AGE, business.industry, GFR, glomerular filtration rate, PTEN, phosphatase and tensin homolog, CI, confidence interval, TC, total cholesterol, SD-rat, Sprague–Dawley rat, UAER, urinary albumin excretion rate, DKD, diabetic kidney disease, T, treatment group, Molecular targets, Therapeutics. Pharmacology, α-SMA, α smooth muscle actin, SD, standard deviation, business, DAG, diacylglycerol, GCLC, glutamate-cysteine ligase catalytic subunit, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d8ab4193adc39b242fa3c089b4f517Test
https://doi.org/10.1016/j.apsb.2020.12.020Test

المؤلفون: Chun-Chia Chen, Mei-Li Wu, Robert J. Doerksen, Chi-Tang Ho, Tzou-Chi Huang

المصدر: Journal of Functional Foods, Vol 14, Iss , Pp 226-235 (2015)

مصطلحات موضوعية: Andrographolide, Glyoxalase 1, Glutamate-cysteine ligase catalytic subunit, HMG-CoA reductase, Apoptosis, Nutrition. Foods and food supply, TX341-641

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S1756464615000523Test; https://doaj.org/toc/1756-4646Test

الوصول الحر: https://doaj.org/article/a74499abc2bf46d6bddede4bdf91a69fTest

المؤلفون: YA Bocharova

المصدر: Features of HIV and SARS-CoV-2 coinfection in a pandemic. :19-23

مصطلحات موضوعية: 0303 health sciences, 03 medical and health sciences, 0302 clinical medicine, Chemistry, Ischemic stroke, General Medicine, Glutamate-cysteine ligase catalytic subunit, Molecular biology, Gene, 030217 neurology & neurosurgery, 030304 developmental biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::dd6d4c4b0da11fdeb0a1577497cd6c90Test
https://doi.org/10.24075/brsmu.2021.007Test

المؤلفون: James E. Goldman, Alice Tang, Michelle L. Olsen, Natasha L. Pacheco, Jiangtao Li, Daniel Flint, Brett S. Phinney, Anthony W. Herren, Fatima Khan, Michael R. Heaven

المصدر: Molecular & cellular proteomics : MCP, vol 21, iss 1
Molecular & Cellular Proteomics : MCP

مصطلحات موضوعية: Proteomics, Cnp, 2′,3′-cyclic-nucleotide 3′-phosphodiesterase, Nadk2, NAD kinase 2, mitochondrial, Pck2, phosphoenolpyruvate carboxykinase [GTP], mitochondrial, Slc16a1, monocarboxylate transporter 1, PPAR, peroxisome proliferator-activated receptor, Mog, myelin-oligodendrocyte glycoprotein, Nfe2l2, nuclear factor erythroid 2-related factor 2, Mlc1, membrane protein MLC1, Biochemistry, C1qc, complement C1q subcomponent subunit C, Transgenic, Analytical Chemistry, Acadl, Long-chain specific acyl-CoA dehydrogenase, mitochondrial, Myelin, Mice, Gsr, glutathione reductase, mitochondrial, Cryl1, lambda-crystallin homolog, Sqstm1, sequestosome-1, BCA, bicinchoninic acid assay, LC3, microtubule-associated protein 1A/1B-light chain 3, Gliosis, SRM, selected reaction monitoring, Aetiology, Gclm, glutamate--cysteine ligase regulatory subunit, μDIA, micro-data-independent acquisition, Acsl3, long-chain-fatty-acid--CoA ligase 3, Cat, catalase, Acot2, Acyl-coenzyme A thioesterase 2, Glial fibrillary acidic protein, Rps27a, ubiquitin-40S ribosomal protein S27a, Acsl6, long-chain-fatty-acid--CoA ligase 6, Aldh1l1, Cytosolic 10-formyltetrahydrofolate dehydrogenase, Slc25a18, mitochondrial glutamate carrier 2, Bsn, protein bassoon, Fabp7, fatty acid binding protein, brain, Plp1, myelin proteolipid protein, Gsta3, glutathione S-transferase A3, Prdx6, peroxiredoxin-6, Alexander Disease, Slc6a11, sodium- and chloride-dependent GABA transporter 3, Ccnd2, G1/S-specific cyclin-D2, Stxbp5l, syntaxin-binding protein 5-like, GAPDH, glyceraldehyde 3 phosphate dehydrogenase, Slc6a17, sodium-dependent neutral amino acid transporter SLC6A17, Biochemistry & Molecular Biology, Ilk, integrin-linked protein kinase, Kcnj10, ATP-sensitive inward rectifier potassium channel 10, Ugt8, Gan, gigaxonin, Ttyh1, protein tweety homolog 1, Hsp27, heat shock protein beta-1, TBI, traumatic brain injury, reactive gliosis, Hmgcs2, hydroxymethylglutaryl-CoA synthase, mitochondrial, Idh2, isocitrate dehydrogenase [NADP], mitochondrial, KEGG, Kyoto encyclopedia of genes and genomes, Genetics, Humans, Gpr37l1, prosaposin receptor GPR37L1, Molecular Biology, Txnrd1, thioredoxin reductase 1, cytoplasmic, Slc38a3, sodium-coupled neutral amino acid transporter 3, Animal, DAVID, database for annotation, visualization and integrated discovery, GFAP, glial fibrillary acidic protein, astrocytes, Rack1, receptor of activated protein C kinase 1, Ugt8, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Apoa1, apolipoprotein A-I, medicine.disease, Oligodendrocyte, GABA, gamma aminobutyric acid, Slc27a1, long-chain fatty acid transport protein 1, nervous system, Fabp7, Mutation, Mag, myelin-associated glycoprotein, Gclc, glutamate--cysteine ligase catalytic subunit, Gsto1, glutathione S-transferase omega-1, Ephx1, epoxide hydrolase 1, Gpx1, glutathione peroxidase 1, C1qa, complement C1q subcomponent subunit A, MDD, major depressive disorder, Cd44, Cd44 antigen, Slc4a4, electrogenic sodium bicarbonate cotransporter 1, Neurodegenerative, Dlg4, disks large homolog 4, TIC, total ion current, Gstm1, glutathione S-transferase Mu 1, Alexander disease, 2.1 Biological and endogenous factors, Functional ability, Ndrg2, protein NDRG2, Sfxn5, sideroflexin-5, Ca2, carbonic anhydrase 2, S1pr1, sphingosine 1-phosphate receptor 1, Gpx3, glutathione peroxidase 3, Snap25, synaptosomal-associated protein 25, Sparcl1, SPARC-like protein 1, medicine.diagnostic_test, Prdx1, peroxiredoxin-1, medicine.anatomical_structure, Neurological, Pgd, 6-phosphogluconate dehydrogenase, decarboxylating, Mbp, myelin basic protein, LPA, lysophosphatidic acid, Astrocyte, Gss, glutathione synthetase, Stat3, signal transducer and activator of transcription 3, Biotechnology, Sorbs1, Sorbin and SH3 domain-containing protein 1, RFs, Rosenthal fibers, Pygb, glycogen phosphorylase, brain form, Ctsd, cathepsin D, Ddx3x, ATP-dependent RNA helicase DDX3X, Fasn, fatty acid synthase, Slc1a2, excitatory amino acid transporter 2, PPP, pentose phosphate pathway, Mice, Transgenic, Plpp3, phospholipid phosphatase 3, Biology, C1qb, complement C1q subcomponent subunit B, CNS, central nervous system, Gja1, gap junction alpha-1 protein, PRM-MS, parallel reaction monitoring-mass spectrometry, TFA, trifluoro acetic acid, Vim, vimentin, Rare Diseases, Western blot, Downregulation and upregulation, Acox1, peroxisomal acyl-coenzyme A oxidase 1, Mobp, myelin-associated oligodendrocyte basic protein, medicine, Atp1b2, sodium/potassium-transporting ATPase subunit beta-2, Animals, Cryab, alpha-crystallin B chain, MS2, MS/MS or tandem mass spectrometry, Research, Neurosciences, Molecular biology, Ntrk2, BDNF/NT-3 growth factors receptor, Brain Disorders, AxD, Alexander disease, Disease Models, Animal, Acox3, Peroxisomal acyl-coenzyme A oxidase 3, Disease Models, biology.protein, Ugp2, UTP--glucose-1-phosphate uridylyl transferase, Acot1, Acyl-coenzyme A thioesterase 1

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27db73f1a1ae5cb5705d0a860adbda89Test
https://hdl.handle.net/10919/111277Test