دورية أكاديمية
Caged Xanthones and Biphenyls Isolated from the Tropical Plant Garcinia lateriflora
| العنوان: | Caged Xanthones and Biphenyls Isolated from the Tropical Plant Garcinia lateriflora |
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| المؤلفون: | Ayano Kobayashi, Yohei Saito, Katsunori Miyake, Shuichi Fukuyoshi, David J. Newman, Barry R. O’Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa-Goto |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Pharmacology, Ecology, Cancer, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, garcinia lateriflora <, four biphenyl derivatives, cytotoxic hexacyclic caged, 2 , 50 , new caged, tropical plant, resistant line, phytochemical study, newly isolated, isolated compounds, clusiaceae ), biphenyls isolated, antiproliferative activity, 7 μm, (< b |
| الوصف: | Four cytotoxic heptacyclic caged-xanthones [gambogefic acids B–E ( 1 – 4 )], a cytotoxic hexacyclic caged-xanthone [garcilatelic acid ( 5 )], and four biphenyl derivatives [garcilatelibiphenyls A–D ( 6 – 9 )] were newly isolated in a phytochemical study of a 50% MeOH/CH 2 Cl 2 extract of Garcinia lateriflora (Clusiaceae). The isolated compounds were evaluated for antiproliferative activity against five human tumor cell lines including a vincristine-resistant line. The new caged-xanthones displayed potent activity with IC 50 values from 0.5 to 6.7 μM against all tested tumor cell lines. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | https://figshare.com/articles/journal_contribution/Caged_Xanthones_and_Biphenyls_Isolated_from_the_Tropical_Plant_i_Garcinia_lateriflora_i_/25041034Test |
| DOI: | 10.1021/acs.jnatprod.3c00934.s001 |
| الإتاحة: | https://doi.org/10.1021/acs.jnatprod.3c00934.s001Test https://figshare.com/articles/journal_contribution/Caged_Xanthones_and_Biphenyls_Isolated_from_the_Tropical_Plant_i_Garcinia_lateriflora_i_/25041034Test |
| حقوق: | CC BY-NC 4.0 |
| رقم الانضمام: | edsbas.BB81D83F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1021/acs.jnatprod.3c00934.s001 |
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