-
1دورية أكاديمية
المؤلفون: Fabian Schneider, Yinliang Guo, You-Chen Lin, Kelly J. Eberle, Debora Chiodi, Johnathan A. Greene, Chenxin Lu, Phil S. Baran
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Biotechnology, Mental Health, Chemical Sciences not elsewhere classified, two disparate β, navigate inherently sensitive, medicinal chemistry studies, epimerizable functional groups, convergent approach proceeds, first total synthesis, total synthesis, unique maneuvers, synthesis enlists, numerous analogues, complex decapeptide, commercial materials, 16 steps
العلاقة: https://figshare.com/articles/journal_contribution/Total_Synthesis_of_Dynobactin_A/25326237Test
الإتاحة: https://doi.org/10.1021/jacs.3c11560.s001Test
https://figshare.com/articles/journal_contribution/Total_Synthesis_of_Dynobactin_A/25326237Test -
2دورية أكاديمية
المؤلفون: Xin Wang, Mengjiao Zhang, Xiaolei Liu, Mingliang Lou, Gen Li, Xiangbing Qi
مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Physiology, Ecology, Marine Biology, Computational Biology, Chemical Sciences not elsewhere classified, double oxidative rearrangement, (±)- 7 (<, pot reaction cascade, >)- geissoschizol oxindole, first total synthesis, total synthesis, geissoschizol oxindoles, formal synthesis, successfully applied, significant potential, reversed stereochemistry, nucleophilic cyclization, natural products, mannich cascade, indole followed, complex structures, c3 epimers
الإتاحة: https://doi.org/10.1021/acs.orglett.3c03938.s001Test
https://figshare.com/articles/journal_contribution/Total_Synthesis_of_Tetracyclic_Spirooxindole_Alkaloids_via_a_Double_Oxidative_Rearrangement_Cyclization_Cascade/25024426Test -
3دورية أكاديمية
المؤلفون: Kosho Makino, Rio Fukuda, Shunsuke Sueki, Masahiro Anada
مصطلحات موضوعية: Biophysics, Biochemistry, Physiology, Biotechnology, Ecology, Plant Biology, Virology, Chemical Sciences not elsewhere classified, phenolic mom ether, solvent provides 1, first total synthesis, cadinane sesquiterpenoid alanense, 2 sub, total synthesis, p <, key step, disubstituted tetrahydronaphthalene, combinatorial use, also found, >- tsoh
الإتاحة: https://doi.org/10.1021/acs.joc.3c02481.s001Test
https://figshare.com/articles/journal_contribution/Total_Synthesis_of_Alanense_A_through_an_Intramolecular_Friedel_Crafts_Alkylation/25029469Test -
4دورية أكاديمية
المؤلفون: Soumyakanta Maji, Balasaheb K. Ghotekar, Suvarn S. Kulkarni
مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Biotechnology, Immunology, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vibrio cholerae <, tetrasaccharide repeating unit, notoriously reactive ascarylose, longest linear sequence, key challenges encountered, higher carbon sugar, first total synthesis, total synthesis, stereoselective glycosylation, poor nucleophilicity, overall yield, completed via, axial c4, antigen polysaccharide, amide coupling, 23 steps
الإتاحة: https://doi.org/10.1021/acs.orglett.3c04225.s001Test
https://figshare.com/articles/journal_contribution/Total_Synthesis_of_a_Conjugation-Ready_Tetrasaccharide_Repeating_Unit_of_i_Vibrio_cholerae_i_O_3_O_antigen_Polysaccharide/24977975Test -
5دورية أكاديمية
المؤلفون: Sukhyun Lee, Young Ho Rhee
مصطلحات موضوعية: Biophysics, Biochemistry, Physiology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, de novo <, first total synthesis, 2 sub, total synthesis, target compounds, stage functionalization, signature step, sequential transition, purported structure, pentasaccharide skeleton, monosaccharide alkoxyallene, mild conditions, efficient preparation, catalyzed coupling
الإتاحة: https://doi.org/10.1021/acs.orglett.3c03808.s001Test
https://figshare.com/articles/journal_contribution/Total_Synthesis_of_the_Purported_Structure_of_Branched_Resin_Glycosides_Merremoside_G_and_H_sub_2_sub_/24982203Test -
6دورية أكاديمية
المؤلفون: Jack Buntine, Samrat Dasgupta, Keely Dorney, Oscar Rubinstein, Mina Salimimarand, Jonathan M. White, Mark A. Rizzacasa
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Molecular Biology, Physiology, Sociology, Inorganic Chemistry, Plant Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, organocatalyzed asymmetric self, aldol reaction followed, acetate aldol reaction, final steps involved, myxobacteria metabolite icumazole, first total synthesis, total synthesis, key steps, stereotriad present, stereoselective reduction, selective methylation, route include, oxazole moiety, acetylide addition, >- diene
الإتاحة: https://doi.org/10.1021/acs.orglett.3c04268.s001Test
https://figshare.com/articles/journal_contribution/Total_Synthesis_of_Icumazole_A_Using_a_Modified_Cadiot_Chodkiewicz_Coupling/25104085Test -
7دورية أكاديمية
المؤلفون: Jian Xiao, Hao Wu, Jia-Rong Liang, Ping Wu, Chen Guo, Ya-Wen Wang, Zhi-Yi Wang, Yu Peng
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Physiology, Biotechnology, Developmental Biology, Cancer, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, subsequent reductive coupling, photocatalytic radical cascade, nickel dual catalysis, first total synthesis, chiral 10 -<, c12 hydroxyl group, abietane 10 -<, anticancer activity evaluation, >- trig cyclization, better activity, >- prbr, >- epoxyhinoliol, thus achieved, six steps, simplified analogue, inhibitory tests, efficient assembly, critical role
الإتاحة: https://doi.org/10.1021/acs.orglett.3c03811.s001Test
https://figshare.com/articles/journal_contribution/Photocatalytic_Tandem_Radical_Cyclization_Enables_Expeditious_Total_Synthesis_of_Epoxyhinokiol_Analogues_for_Anticancer_Activity_Evaluation/25029376Test -
8دورية أكاديمية
المؤلفون: Yating Liu, Mengkun Yan, Minghui Wang, Shiwei Luo, Shasha Wang, Yawen Luo, Zhuojia Xu, Wenjing Ma, Liuqing Wen, Tiehai Li
مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Space Science, Chemical Sciences not elsewhere classified, two sialic acids, two sequential enzyme, presenting multivalent interactions, oxazoline disaccharide donor, associated complex glycosphingolipid, first total synthesis, challenging internal α2, assisted enzymatic α2, synthesize dsgb5 glycosphingolipid, exclusively form β, binding results suggest, efficient chemoenzymatic approach, chemoenzymatic synthesis, unique aspect, substrate specificity, structurally well, stereoselective installment, sialyltransferase st6galnac5, sialyltransferase cst, oligosaccharide moiety, method using, linked sialoside, glycan epitope, gb5 pentasaccharide, dsgb5 glycolipid
الإتاحة: https://doi.org/10.1021/acscentsci.3c01170.s001Test
https://figshare.com/articles/journal_contribution/Stereoconvergent_and_Chemoenzymatic_Synthesis_of_Tumor-Associated_Glycolipid_Disialosyl_Globopentaosylceramide_for_Probing_the_Binding_Affinity_of_Siglec_7/25057537Test -
9دورية أكاديمية
المؤلفون: Darryl M. Wilson, Robert Britton
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Pharmacology, Biotechnology, Evolutionary Biology, Ecology, Marine Biology, Inorganic Chemistry, Chemical Sciences not elsewhere classified, potent anticancer agent, first total synthesis, enantioselective total synthesis, marine macrolides salarins, synthesis relies, synthesis include, work provides, side chain, proline catalysis, potentially mimics, macrocyclic substrate, key features, controlled epoxidation, containing salarins, closing metathesis, chlorohydrin function, access salarin
-
10دورية أكاديمية
المؤلفون: Haoting Li, Ansley M. Nemeth, Roberta J. Melander, Christian Melander
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Pharmacology, Biotechnology, Sociology, Science Policy, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, thereby reducing dosage, minimum inhibitory concentration, acinetobacter baumannii <, negative outer membrane, increasing antibiotic efficacy, potent variabiline derivatives, first total synthesis, derivatives potentiate colistin, augment antibiotic activity, negative bacteria, recently identified, one approach, new antibiotics, molecule potentiators, led physicians, last resort, known nephrotoxicity, klebsiella pneumoniae, infections caused